Exposure Assessment
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Exposure Assessment
Exposure assessment is a branch of environmental science and occupational hygiene that focuses on the processes that take place at the interface between the environment containing the contaminant of interest and the organism being considered. These are the final steps in the path to release an environmental contaminant, through transport to its effect in a biological system. It tries to measure how much of a contaminant can be absorbed by an exposed target organism, in what form, at what rate and how much of the absorbed amount is actually available to produce a biological effect. Although the same general concepts apply to other organisms, the overwhelming majority of applications of exposure assessment are concerned with human health, making it an important tool in public health. Definition Exposure assessment is the process of estimating or measuring the magnitude, frequency and duration of exposure to an agent, along with the number and characteristics of the population exp ...
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Environmental Science
Environmental science is an interdisciplinary academic field that integrates physics, biology, and geography (including ecology, chemistry, plant science, zoology, mineralogy, oceanography, limnology, soil science, geology and physical geography, and atmospheric science) to the study of the environment, and the solution of environmental problems. Environmental science emerged from the fields of natural history and medicine during the Enlightenment. Today it provides an integrated, quantitative, and interdisciplinary approach to the study of environmental systems. Environmental studies incorporates more of the social sciences for understanding human relationships, perceptions and policies towards the environment. Environmental engineering focuses on design and technology for improving environmental quality in every aspect. Environmental scientists seek to understand the earth’s physical, chemical, biological, and geological processes, and to use that knowledge to understan ...
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Pollutant
A pollutant or novel entity is a substance or energy introduced into the environment that has undesired effects, or adversely affects the usefulness of a resource. These can be both naturally forming (i.e. minerals or extracted compounds like oil) or anthropogenic in origin (i.e. manufactured materials or byproducts from biodegradation). Pollutants result in environmental pollution or become public health concerns when they reach a concentration high enough to have significant negative impacts. A pollutant may cause long- or short-term damage by changing the growth rate of plant or animal species, or by interfering with human amenities, comfort, health, or property values. Some pollutants are biodegradable and therefore will not persist in the environment in the long term. However, the degradation products of some pollutants are themselves polluting such as the products DDE and DDD produced from the degradation of DDT. Pollution has widespread negative impacts on the enviro ...
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Environmental Monitoring
Environmental monitoring describes the processes and activities that need to take place to characterize and monitor the quality of the environment. Environmental monitoring is used in the preparation of environmental impact assessments, as well as in many circumstances in which human activities carry a risk of harmful effects on the natural environment. All monitoring strategies and programs have reasons and justifications which are often designed to establish the current status of an environment or to establish trends in environmental parameters. In all cases, the results of monitoring will be reviewed, analyzed statistically, and published. The design of a monitoring program must therefore have regard to the final use of the data before monitoring starts. Environmental monitoring includes monitoring of air quality, soils and water quality. Air quality monitoring Air pollutants are atmospheric substances—both naturally occurring and anthropogenic—which may potentially ...
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Biomarkers Of Exposure Assessment
Biomarkers in analytical chemistry and in environmental science are chemicals, metabolites, susceptibility characteristics, or changes in the body that relate to the exposure of an organism to a chemical. They have the ability to identify if an exposure has occurred, the route of exposure, the pathway of exposure, and the resulting effects of the exposure. The use of biomarkers in exposure studies is also referred to as biomonitoring. When dealing with exposure assessment, there are three types of biomarkers that can be useful, biomarkers of susceptibility, biomarkers of exposure, and biomarkers of effect. Biomarkers of exposure are the most widely used because they can provide information on the route, pathway, and sometimes, even the source of exposure. Biomarkers of susceptibility Biomarkers of susceptibility are indicators of the natural characteristics of an organism that make it more susceptible to the effects of an exposure to a chemical. They can help define what sensitivi ...
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Biomonitoring
In analytical chemistry, biomonitoring is the measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological substances. Often, these measurements are done in blood and urine. Biomonitoring is performed in both environmental health, and in occupational safety and health as a means of exposure assessment and workplace health surveillance. The two best established environmental biomonitoring programs in representative samples of the general population are those of the United States and Germany, although population-based programs exist in a few other countries. In 2001, the U.S. Centers for Disease Control and Prevention (CDC) began to publish its biennial ''National Report on Human Exposure to Environmental Chemicals'', which reports a statistically representative sample of the U.S. population. Overview Biomonitoring involves the use of organisms to assess environmental contamination, such as of surrounding air or water. It can be done ...
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Workplace Exposure Monitoring
Workplace exposure monitoring is the monitoring of substances in a workplace that are chemical or biological hazards. It is performed in the context of workplace exposure assessment and risk assessment. Exposure monitoring analyzes hazardous substances in the air or on surfaces of a workplace, and is complementary to biomonitoring, which instead analyzes toxicants or their effects within workers. A wide array of methods and instrumentation are used in workplace exposure monitoring. Direct-read instruments give immediate data, and include colorimetric Colorimetry is "the science and technology used to quantify and describe physically the human color perception". It is similar to spectrophotometry, but is distinguished by its interest in reducing spectra to the physical correlates of color ... indicators such as gas detector tubes, and electronic devices such as Gas detector, gas monitors and aerosol Particle counter, particle counters. In addition, samples may be collecte ...
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Biomarker
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. as cited in Biomarkers are used in many scientific fields. Medicine Biomarkers used in the medical field, are a part of a relatively new clinical toolset categorized by their clinical applications. The three main classes are molecular biomarkers, cellular biomarkers or imaging biomarkers. All three types of biomarkers have a clinical role in narrowing or guiding treatment decisions and follow a sub-categorization of being either predictive, prognostic, or diagnostic. Predictive Predictive molecular, cellular, or imaging biomarkers that pass validation can serve as a method of predicting clinical outcomes. Predictive biomarkers are used to help optimize id ...
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NIOSH HHE - Measuring Contaminants On Workers’ Skin And Workplace Surfaces
The National Institute for Occupational Safety and Health (NIOSH, ) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. NIOSH is part of the Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services. Despite its name, it is not part of the National Institutes of Health. Its current director is John Howard. NIOSH is headquartered in Washington, D.C., with research laboratories and offices in Cincinnati, Ohio; Morgantown, West Virginia; Pittsburgh, Pennsylvania; Denver, Colorado; Anchorage, Alaska; Spokane, Washington; and Atlanta, Georgia. NIOSH is a professionally diverse organization with a staff of 1,200 people representing a wide range of disciplines including epidemiology, medicine, industrial hygiene, safety, psychology, engineering, chemistry, and statistics. The Occupational Safety and Health Act, signed by President Ric ...
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NIOSH Health Hazard Evaluation Program - Measuring Contaminants In The Air At A Workplace
The National Institute for Occupational Safety and Health (NIOSH, ) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. NIOSH is part of the Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services. Despite its name, it is not part of the National Institutes of Health. Its current director is John Howard. NIOSH is headquartered in Washington, D.C., with research laboratories and offices in Cincinnati, Ohio; Morgantown, West Virginia; Pittsburgh, Pennsylvania; Denver, Colorado; Anchorage, Alaska; Spokane, Washington; and Atlanta, Georgia. NIOSH is a professionally diverse organization with a staff of 1,200 people representing a wide range of disciplines including epidemiology, medicine, industrial hygiene, safety, psychology, engineering, chemistry, and statistics. The Occupational Safety and Health Act, signed by President Ric ...
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Water Chlorination
Water chlorination is the process of adding chlorine or chlorine compounds such as sodium hypochlorite to water. This method is used to kill bacteria, viruses and other microbes in water. In particular, chlorination is used to prevent the spread of waterborne diseases such as cholera, dysentery, and typhoid. History In a paper published in 1894, it was formally proposed to add chlorine to water to render it "germ-free". Two other authorities endorsed this proposal and published it in many other papers in 1895. Early attempts at implementing water chlorination at a water treatment plant were made in 1893 in Hamburg, Germany. In 1897 the town of Maidstone, England was the first to have its entire water supply treated with chlorine. Permanent water chlorination began in 1905, when a faulty slow sand filter and a contaminated water supply caused a serious typhoid fever epidemic in Lincoln, England. Alexander Cruickshank Houston used chlorination of the water to stop the epidemic. ...
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Inhalation Exposure
Inhalation is a major route of exposure that occurs when an individual breathes in polluted air which enters the respiratory tract. Identification of the pollutant uptake by the respiratory system can determine how the resulting exposure contributes to the dose. In this way, the mechanism of pollutant uptake by the respiratory system can be used to predict potential health impacts within the human population. Definition Exposure is commonly understood to be the concentration of the airborne pollutant in the air at the mouth and nose boundary. Outdoor concentrations are often measured at fixed sites or estimated with models. The fraction of this ambient concentration that is inhaled by a person depends mainly on their location (indoor or outdoor), distance to pollution sources and their minute ventilation. Traditionally exposure is estimated based on outdoor concentrations at the residential address. Trips to other locations and physical activity level are mostly neglected alth ...
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