Excimer Laser Trabeculostomy
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Excimer Laser Trabeculostomy
Excimer laser trabeculostomy (ELT) is a procedure to create holes in the trabecular meshwork to reduce intraocular pressure. It uses a XeCl 308 nm excimer laser An excimer laser, sometimes more correctly called an exciplex laser, is a form of ultraviolet laser which is commonly used in the production of microelectronic devices, semiconductor based integrated circuits or "chips", eye surgery, and microm .... It is considered a minimally invasive glaucoma surgeries, and was described in 1987 by Dr. Michael Berlin. References {{reflist Eye surgery ...
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Trabecular Meshwork
The trabecular meshwork is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). The tissue is spongy and lined by trabeculocytes; it allows fluid to drain into a set of tubes called Schlemm's canal which is lined by endothelium with blood and lymphatic properties that allow aqueous humor to flow into the blood system. Structure The meshwork is divided up into three parts, with characteristically different ultrastructures: #''Inner uveal meshwork'' - Closest to the anterior chamber angle, contains thin cord-like trabeculae, orientated predominantly in a radial fashion, enclosing trabeculae spaces larger than the corneoscleral meshwork. #''Corneoscleral meshwork'' - Contains a large amount of elastin, arranged as a series of thin, flat, perforated sheets arranged in a laminar pattern; cons ...
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Intraocular Pressure
Intraocular pressure (IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. Most tonometers are calibrated to measure pressure in millimeters of mercury ( mmHg). Physiology Intraocular pressure is determined by the production and drainage of aqueous humour by the ciliary body and its drainage via the trabecular meshwork and uveoscleral outflow. The reason for this is because the vitreous humour in the posterior segment has a relatively fixed volume and thus does not affect intraocular pressure regulation. An important quantitative relationship (Goldmann's equation) is as follows: :P_o = \frac + P_v Where: * P_o is the IOP in millimeters of mercury (mmHg) * F the rate of aqueous humour formation in microliters per minute (μL/min) * U the resorption of aqueous humour through the uveoscleral route (μL/min) * C is the facility of outflow in micr ...
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Xenon Monochloride
Xenon monochloride (XeCl) is an exciplex which is used in excimer lasers and excimer lamps emitting near ultraviolet light at 308 nm. It is most commonly used in medicine. Xenon monochloride was first synthesized in the 1960s. Its kinetic scheme is very complex and its state changes occur on a nanosecond timescale. In the gaseous state, at least two kinds of xenon monochloride are known: XeCl and , whereas complex aggregates form in the solid state in noble gas matrices. The excited state of xenon resembles halogens and it reacts with them to form excited molecular compounds. Introduction Molecules that are only stable in electronically excited states are called excimer molecules, but may be called exciplex molecules if they are heteronuclear. The exciplex halides constitute an important class of rare gas halides with formula RgX. Rg is the noble gas, and X is the halogen. These molecules are de-excited by emitting a photon whose energy is some Electronvolts. Theref ...
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Excimer Laser
An excimer laser, sometimes more correctly called an exciplex laser, is a form of ultraviolet laser which is commonly used in the production of microelectronic devices, semiconductor based integrated circuits or "chips", eye surgery, and micromachining. Since 1960s excimer lasers are widely used in high-resolution photolithography machines, one of the critical technologies required for microelectronic chip manufacturing. Terminology and history The term excimer is short for 'excited dimer', while exciplex is short for 'excited complex'. Most excimer lasers are of the noble gas halide type, for which the term ''excimer'' is, strictly speaking, a misnomer. (Although less commonly used, the proper term for such is an exciplex laser.) Excimer laser was proposed in 1960 by Fritz Houtermans. The excimer laser development started with the observation of a nascent spectral line narrowing at 176 nm  reported in 1971 by Nikolai Basov, V. A. Danilychev and Yu. M. Popov, at the Leb ...
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Minimally Invasive Glaucoma Surgery
Micro-invasive glaucoma surgery (MIGS) is the latest advance in surgical treatment for glaucoma, which aims to reduce intraocular pressure by either increasing outflow of aqueous humor or reducing its production. MIGS comprises a group of surgical procedures which share common features. MIGS procedures involve a minimally invasive approach, often with small cuts or micro-incisions through the cornea that causes the least amount of trauma to surrounding scleral and conjunctival tissues. The techniques minimize tissue scarring, allowing for the possibility of traditional glaucoma procedures such as trabeculectomy or glaucoma valve implantation (also known as glaucoma drainage device) to be performed in the future if needed.Minimally Invasive Glaucoma Surgeries< ...
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