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Estratest
Esterified estrogens/methyltestosterone (EEs/MT), sold under brand names such as Covaryx, Eemt, Essian, Estratest, Menogen, and Syntest, is a hormonal preparation that combines esterified estrogens (EEs) with methyltestosterone (MT) in one tablet and is used in menopausal hormone therapy. Medical uses EEs/MT is used to treat menopausal women who suffer from hot flashes, but do not get relief from estrogen-only therapy. Available forms EEs/MT is sold in tablet form, with either 1.25 mg EEs/2.5 mg MT or 0.625 mg EEs/1.25 mg MT available. Pharmacology The product is a combination of esterified estrogens, an estrogen, and low-dose methyltestosterone, an androgen/anabolic steroid, in a single tablet. History EEs/MT was first marketed in the United States in 1965 by Reid-Provident Laboratories, which as 100% of Reid-Rowell, Inc. stock was acquired by the Belgian pharmaceutical company Solvay in 1986. There has been some controversy surrounding the drug in recent years as to its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methyltestosterone
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women. It is taken by mouth or held in the cheek or under the tongue. Side effects of methyltestosterone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. It can also cause estrogenic effects like fluid retention, breast tenderness, and breast enlargement in men and liver damage. The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has moderate androgenic effects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esterified Estrogens
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men. It is formulated alone or in combination with methyltestosterone. It is taken by mouth. Side effects of EEs include nausea, breast tension, edema, and breakthrough bleeding among others. It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. EEs were introduced for medical use by 1970. They are available in only a few countries, such as Chile and the United States. They have also been marketed in Argentina and Switzerland in the past. Medical uses EEs are used in hormone therapy for menopausal symptoms, female hypogonadism, ovariectomy, and primary ovarian ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esterified Estrogen
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men. It is formulated alone or in combination with methyltestosterone. It is taken by mouth. Side effects of EEs include nausea, breast tension, edema, and breakthrough bleeding among others. It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. EEs were introduced for medical use by 1970. They are available in only a few countries, such as Chile and the United States. They have also been marketed in Argentina and Switzerland in the past. Medical uses EEs are used in hormone therapy for menopausal symptoms, female hypogonadism, ovariectomy, and primary ovarian f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Combined Sex-hormonal Preparations
This is a list of known combined sex-hormonal formulations. Brand names and developmental code names are in parentheses. Androgens Injection Marketed * Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol) * Testosterone propionate/testosterone isocaproate/testosterone caproate (Androteston PP) * Testosterone propionate/testosterone enanthate/testosterone undecylenate (Durasteron) * Testosterone propionate/testosterone enanthate (Testoviron Depot) * Testosterone propionate/testosterone ketolaurate (Testosid Depot) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Sustanon 100) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate (Omnadren 250) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (Sustanon 250) * Testosterone propionate/testosterone valerate/testosterone undecylenate (Triolandren) * Testosterone propionate/testosterone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacodynamics
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions between both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relationships between d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conjugated Estrogens/methyltestosterone
Conjugated estrogens/methyltestosterone (CEEs/MT), sold under the brand name Premarin with Methyltestosterone, is a combination of conjugated estrogens (CEEs), an estrogen, and methyltestosterone (MT), an androgen and anabolic steroid (AAR), which is used in menopausal hormone therapy for women. It contains 0.625 to 1.25 mg CEEs and 5 to 10 mg MT. The medication was marketed by Wyeth-Ayerst. CEEs/MT was previously marketed in the United States and Canada. It remains available only in Paraguay, under the brand names Delitan and Delitan Forte. See also * Esterified estrogens/methyltestosterone * List of combined sex-hormonal preparations This is a list of known combined sex-hormonal formulations. Brand names and developmental code names are in parentheses. Androgens Injection Marketed * Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol) * Testosterone propionate/ ... References Abandoned drugs Combined estrogen–androgen formulations { ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solvay (company)
Solvay is a Belgian multinational chemical company established in 1863, with its headquarters located in Neder-Over-Heembeek, Brussels, Belgium. In 2015, it realized €12.4 billion in revenues, €2.336 billion of EBITDA, 43% of its sales in emerging high-growth countries, 90% of its sales in markets where it is ranked among the top three manufacturers. With 145 sites, Solvay employs 30,900 people in 53 countries. History Founded in 1863 by Ernest Solvay and his brother Alfred Solvay to produce sodium carbonate by the Solvay process, the company has diversified into two main sectors of activity: chemicals and plastics. Before World War I, Solvay was the largest multinational company in the world. It was formerly also active in pharmaceutical industry, pharmaceuticals, but agreed to sell that entire division to Abbott Laboratories, Abbott Labs for €4.5 billion in September 2009, a deal completed in February 2010. In April 2011, the firm agreed to the €3.4 billion acquis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anabolic Steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone (medication), testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone. They increase protein within cell (biology), cells, especially in skeletal muscles, and also have varying degrees of virilization, virilizing effects, including induction of the development and maintenance of male, masculine secondary sexual characteristics such as the growth of facial hair, facial and body hair. The word ''anabolic'', referring to anabolism, comes from the Greek ἀναβολή ''anabole'', "that which is thrown up, mound". Androgens or AAS are one of three types of sex hormone agonists, the others being estrogen (medication), estrogens like estradiol (medication), estradiol and progestogens like progesterone (medication), progesterone. AAS were synthesized in the 1930s, and are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androgen
An androgen (from Greek ''andr-'', the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. The major androgen in males is testosterone. Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. DHT ''in utero'' causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Also, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estrone Sulfate (medication)
Estrone sulfate (E1S) is an estrogen (medication), estrogen medication and naturally occurring steroid hormone. It is used in menopausal hormone therapy among other indications. As the sodium salt (chemistry), salt (sodium estrone sulfate), it is the major estrogen component of conjugated estrogens (Premarin) and esterified estrogens (Estratab, Menest). In addition, E1S is used on its own as the piperazine salt estropipate (piperazine estrone sulfate; Ogen). The compound also occurs as a major and important metabolite of estradiol (medication), estradiol and estrone (medication), estrone. E1S is most commonly taken oral administration, by mouth, but in the form of Premarin can also be taken by parenteral routes such as transdermal administration, transdermal, vaginal administration, vaginal, and injection (medicine), injection. Medical uses E1S is used in menopausal hormone therapy among other indications. Pharmacology Pharmacodynamics E1S itself is essentially biological ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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