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Eric R. Gamazon
Eric R. Gamazon is a statistical geneticist in Vanderbilt University, with faculty affiliations in the Division of Genetic Medicine, Data Science Institute, and Center for Precision Medicine. He is a Life Member of Clare Hall, Cambridge University after election to a Visiting Fellowship (2018). Research and career Eric Gamazon has developed computational methods that can be used to identify genes and mechanisms underlying complex diseases. He was a developer of the transcriptome-wide association study (TWAS) methodology (PrediXcan), which integrates gene expression and genome-wide association study data to identify disease-associated genes. Subsequent work integrated Mendelian randomization into TWAS. As of December 2021, he has authored 160 peer-reviewed publications in human genetics, functional genomics, and statistical genetics. He was a co-chair of the Genome-Wide Association Studies Working Group of the Genotype-Tissue Expression (GTEx) project, the National Institutes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical Genetics
Statistical genetics is a scientific field concerned with the development and application of statistical methods for drawing inferences from genetic data. The term is most commonly used in the context of human genetics. Research in statistical genetics generally involves developing theory or methodology to support research in one of three related areas: *population genetics - Study of evolutionary processes affecting genetic variation between organisms *genetic epidemiology - Studying effects of genes on diseases *quantitative genetics - Studying the effects of genes on 'normal' phenotypes Statistical geneticists tend to collaborate closely with geneticists, molecular biologists, clinicians and bioinformaticians. Statistical genetics is a type of computational biology Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genetics
Human genetics is the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling. Genes are the common factor of the qualities of most human-inherited traits. Study of human genetics can answer questions about human nature, can help understand diseases and the development of effective treatment and help us to understand the genetics of human life. This article describes only basic features of human genetics; for the genetics of disorders please see: medical genetics. Genetic differences and inheritance patterns Inheritance of traits for humans are based upon Gregor Mendel's model of inheritance. Mendel deduced that inheritance depends upon discrete units of inheritance, called factors or genes. Autosomal dominant inheritance Autosomal tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Chicago Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vanderbilt University Faculty
Vanderbilt may refer to: People *Vanderbilt (surname) *Vanderbilt family Places In the United States: *Vanderbilt, California, a former gold-mining town *Vanderbilt, Michigan, a village * Vanderbilt, Nevada, a ghost town * Vanderbilt Mansion National Historic Site, Hyde Park, NY * Vanderbilt, Texas, a census-designated place *Vanderbilt, Pennsylvania, a borough *Vanderbilt Avenue, three New York City streets *Vanderbilt University, a private research university in Nashville, Tennessee, USA **Vanderbilt Commodores, the athletics program of Vanderbilt University *Vanderbilt Museum, in Centerport, New York, built with a bequest from William Kissam Vanderbilt II Other uses * One Vanderbilt, a skyscraper in New York City *Vanderbilt Club, a bidding system in the game of contract bridge, devised by Harold S. Vanderbilt *Vanderbilt Cup, in American auto racing * George Vanderbilt Sumatran Expedition *Vanderbilt Mortgage and Finance, specializes in mortgages for manufactured homes *Vande ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academics Of The University Of Cambridge
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of Clare Hall, Cambridge
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Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses *Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical Geneticists
Statistics (from German: ''Statistik'', "description of a state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of surveys and experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey samples. Representative sampling assures that inferences and conclusions can reasonably extend from the sample to the population as a whole. An experim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Geneticists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow Of The Royal Society Of Biology
Fellowship of the Royal Society of Biology (FRSB), previously Fellowship of the Society of Biology (FSB), is an award and fellowship granted to individuals that the Royal Society of Biology has adjudged to have made a "prominent contribution to the advancement of the biological sciences, and has gained no less than five years of experience in a position of senior responsibility". Fellowship Fellows are entitled to use the post-nominal letters FRSB. examples of fellows include David Attenborough, Martin Hume Johnson, Jasmin Fisher and Nancy Rothwell Dame Nancy Jane Rothwell (born 2 October 1955) is a British physiologist. She has served as president and vice-chancellor of the University of Manchester since July 2010, having served as Deputy President and Deputy Vice-Chancellor until Januar .... See the : Fellows of the Royal Society of Biology for more examples. References {{Reflist Royal Society of Biology Academic awards * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute On Aging
The National Institute on Aging (NIA) is a division of the U.S. National Institutes of Health (NIH), located in Bethesda, Maryland. The NIA itself is headquartered in Baltimore, Maryland. The NIA leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. In 1974, under Public Law 93-296, Congress granted authority to form NIA to provide leadership in aging research, training, health information dissemination, and other programs relevant to aging and older people. In January 2011, President Obama signed into law the National Alzheimer’s Project Act, designating the NIA as the primary federal agency on Alzheimer's disease research. NIA is led by Director, Richard J. Hodes, M.D, and Acting Deputy Director Melinda Kelley, M.D. Mission NIA's mission is to improve the health and well-being of older Americans through research, and specifically to: *Support and conduct high-quality research on: **Aging processes **Age-related dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precision Medicine
Precision, precise or precisely may refer to: Science, and technology, and mathematics Mathematics and computing (general) * Accuracy and precision, measurement deviation from true value and its scatter * Significant figures, the number of digits that carry real information about a measurement * Precision and recall, in information retrieval: the proportion of relevant documents returned * Precision (computer science), a measure of the detail in which a quantity is expressed * Precision (statistics), a model parameter or a quantification of precision Computing products * Dell Precision, a line of Dell workstations * Precision Architecture, former name for PA-RISC, a reduced instruction set architecture developed by Hewlett-Packard * Ubuntu 12.04 "Precise Pangolin", Canonical's sixteenth release of Ubuntu Companies * Precision Air, an airline based in Tanzania * Precision Castparts Corp., a casting company based in Portland, Oregon, in the United States * Precision Drilling ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Expression Quantitative Trait Loci
Expression quantitative trait loci (eQTLs) are genomic loci that explain variation in expression levels of mRNAs. Distant and local, trans- and cis-eQTLs, respectively An expression quantitative trait is an amount of an mRNA transcript or a protein. These are usually the product of a single gene with a specific chromosomal location. This distinguishes expression quantitative traits from most complex traits, which are not the product of the expression of a single gene. Chromosomal loci that explain variance in expression traits are called eQTLs. eQTLs located near the gene-of-origin (gene which produces the transcript or protein) are referred to as local eQTLs or cis-eQTLs. By contrast, those located distant from their gene of origin, often on different chromosomes, are referred to as distant eQTLs or trans-eQTLs. The first genome-wide study of gene expression was carried out in yeast and published in 2002. The initial wave of eQTL studies employed microarrays to measure genome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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