Ergosine
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Ergosine
alpha and beta ergosine Ergosines are ergoloid-like chemicals made by ''Claviceps purpurea ''Claviceps purpurea'' is an ergot fungus that grows on the ears of rye and related cereal and forage plants. Consumption of grains or seeds contaminated with the survival structure of this fungus, the ergot sclerotium, can cause ergotism in h ...''. External links Incorporation of thiazolidine-4-carbozylic acid into ergosine by Claviceps purpurea Ergot alkaloids Indolizidines Lactams {{alkaloid-stub ...
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Ergosine (alpha + Beta)
alpha and beta ergosine Ergosines are ergoloid-like chemicals made by ''Claviceps purpurea ''Claviceps purpurea'' is an ergot fungus that grows on the ears of rye and related cereal and forage plants. Consumption of grains or seeds contaminated with the survival structure of this fungus, the ergot sclerotium, can cause ergotism in hu ...''. External links Incorporation of thiazolidine-4-carbozylic acid into ergosine by Claviceps purpurea Ergot alkaloids Indolizidines Lactams {{alkaloid-stub ...
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Ergoloid
Ergoloid mesylates (USAN), co-dergocrine mesilate ( BAN) or dihydroergotoxine mesylate, trade name Hydergine, is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids ( dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine). It was developed by Albert Hofmann (the discoverer of LSD) for Sandoz (now part of Novartis). Medical uses It has been used to treat dementia and age-related cognitive impairment (such as in Alzheimer disease), as well as to aid in recovery after stroke. A systematic review published in 1994 found little evidence to support the use of ergoloid mesylates, concluding only that potentially effective doses may be higher than those currently approved in dementia treatment. Ergoloid Mesylate Tablets USP for sublingual use contain 1 mg of Ergoloid Mesylates USP, a mixture of the methanesulfonate salt of the following hydrogenated alkaloids: Dihydroergocornine mesylate 0.333 mg, Dihydroergocristi ...
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Claviceps Purpurea
''Claviceps purpurea'' is an ergot fungus that grows on the ears of rye and related cereal and forage plants. Consumption of grains or seeds contaminated with the survival structure of this fungus, the ergot sclerotium, can cause ergotism in humans and other mammals. ''C. purpurea'' most commonly affects outcrossing species such as rye (its most common host), as well as triticale, wheat and barley. It affects oats only rarely. Life cycle An ''ergot kernel'' called ''Sclerotium clavus'' develops when a floret of flowering grass or cereal is infected by an ascospore of ''C. purpurea''. The infection process mimics a pollen grain growing into an ovary during fertilization. Because infection requires access of the fungal spore to the stigma, plants infected by ''C. purpurea'' are mainly outcrossing species with open flowers, such as rye (''Secale cereale'') and Alopecurus. The proliferating fungal mycelium then destroys the plant ovary and connects with the vascular bundle o ...
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Ergot Alkaloids
Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''. The most prominent member of this group is ''Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that can cause ergotism in humans and other mammals who consume grains contaminated with its fruiting structure (called ''ergot sclerotium''). ''Claviceps'' includes about 50 known species, mostly in the tropical regions. Economically significant species include ''C. purpurea'' (parasitic on grasses and cereals), ''C. fusiformis'' (on pearl millet, buffel grass), ''C. paspali'' (on dallis grass), ''C. africana'' (on sorghum), and ''C. lutea'' (on paspalum). ''C. purpurea'' most commonly affects outcrossing species such as rye (its most common host), as well as triticale, wheat, and barley. It affects oats only rarely. ''C. purpurea'' has at least three races or varieties, which differ in their host specificity: *G1 — land grasses of open ...
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