Erbovirus
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Erbovirus
''Erbovirus'' is a genus of viruses in the order ''Picornavirales'', in the family ''Picornaviridae''. Horses serve as natural hosts. There is only one species in this genus: ''Erbovirus A''. Diseases associated with this genus include: upper respiratory tract disease with viremia and fecal shedding. Viruses belonging to the genus ''Erbovirus'' have been isolated in horses with acute upper febrile respiratory disease. The structure of the ''Erbovirus'' virion is icosahedral, having a diameter of 27–30 nm. Physical characteristics Viruses in ''Erbovirus'' are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 8.8kb in length. The virion essentially is a nucleocapsid that is visible under an electron microscope and is able to infect cultured cells from a broad range of mammals including rabbit kidney (RK13), African green monkey kidney (Vero), equine foeta ...
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Acid-stable Equine Picornavirus
Acid-stable equine picornavirus (EqPV) is a member virus of '' Erbovirus A'' in the family ''Picornaviridae.'' They were isolated in the UK and Japan, from nasal swabs of horses with acute febrile respiratory disease. The Erbovirus ''Erbovirus'' is a genus of viruses in the order ''Picornavirales'', in the family ''Picornaviridae''. Horses serve as natural hosts. There is only one species in this genus: ''Erbovirus A''. Diseases associated with this genus include: upper re ... genus includes three serotypes: ERBV1, ERBV2 and ERBV3. References Picornaviridae Infraspecific virus taxa {{virus-stub ...
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Picornaviridae
Picornaviruses are a group of related nonenveloped RNA viruses which infect vertebrates including fish, mammals, and birds. They are viruses that represent a large family of small, positive-sense, single-stranded RNA viruses with a 30 nm icosahedral capsid. The viruses in this family can cause a range of diseases including the common cold, poliomyelitis, meningitis, hepatitis, and paralysis. Picornaviruses constitute the family ''Picornaviridae'', order '' Picornavirales'', and realm '' Riboviria''. There are 158 species in this family, assigned to 68 genera. Notable examples are genera ''Enterovirus'' (including '' Rhinovirus'' and '' Poliovirus''), '' Aphthovirus'', '' Cardiovirus'', and '' Hepatovirus''. Etymology The name "picornavirus" has a dual etymology. Firstly, the name derives from ''picorna''- which is an acronym for "''p''oliovirus, ''i''nsensitivity to ether, ''c''oxsackievirus, ''o''rphan virus, ''r''hinovirus, and ribo''n''ucleic ''a' ...
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Viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material ...
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Picornavirales
''Picornavirales'' is an order of viruses with vertebrate, invertebrate, protist and plant hosts. The name has a dual etymology. First, ''picorna-'' is an acronym for poliovirus, insensitivity to ether, coxsackievirus, orphan virus, rhinovirus, and ribonucleic acid. Secondly, pico-, meaning extremely small, combines with RNA to describe these very small RNA viruses. The order comprises viruses that historically are referred to as picorna-like viruses. Characteristics The families within this order share a number of common features: * The virions are non- enveloped, icosahedral, and about 30 nanometers in diameter. * The capsid has a "pseudo T=3" structure, and is composed of 60 protomers each made of three similar-sized but nonidentical beta barrels. * The genome is made of one or a few single-stranded RNA(s) serving directly as mRNA, without overlapping open reading frames. * The genome has a small protein, VPg, covalently attached to its 5' end, and usually a poly-aden ...
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Nucleocapsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either Helix, helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a Spring (device), spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may ...
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Electron Microscope
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a higher resolving power than light microscopes and can reveal the structure of smaller objects. A scanning transmission electron microscope has achieved better than 50  pm resolution in annular dark-field imaging mode and magnifications of up to about 10,000,000× whereas most light microscopes are limited by diffraction to about 200  nm resolution and useful magnifications below 2000×. Electron microscopes use shaped magnetic fields to form electron optical lens systems that are analogous to the glass lenses of an optical light microscope. Electron microscopes are used to investigate the ultrastructure of a wide range of biological and inorganic specimens including microorganisms, cells, large molecules, biopsy samples, ...
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Aphthovirus
''Aphthovirus'' (from the Greek -, vesicles in the mouth) is a viral genus of the family ''Picornaviridae''. Aphthoviruses infect split-hooved animals, and include the causative agent of foot-and-mouth disease, '' Foot-and-mouth disease virus'' (FMDV). There are seven FMDV serotypes: A, O, C, SAT 1, SAT 2, SAT 3 and Asia 1, and four non-FMDV serotypes belonging to three additional species ''Bovine rhinitis A virus'' (BRAV), ''Bovine rhinitis B virus'' (BRBV) and ''Equine rhinitis A virus'' (ERAV). Structure Aphthoviruses are non-enveloped and have an icosahedral capsid with a diameter of around 27 to 30 nm. The assembled viral capsid contains a single copy of the RNA genome and 60 copies of the four viral capsid proteins VP1, VP2, VP3, and VP4. The protomers form the sides of the icosahedral capsid. The VP4 protein is internal. Genome The aphthoviruses are differentiated from other picornaviruses as they have a larger genome (7.5–8.5 kilobases). The genome is ...
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Foot-and-mouth Disease
Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, followed by blisters inside the mouth and near the hoof that may rupture and cause lameness. FMD has very severe implications for animal farming, since it is highly infectious and can be spread by infected animals comparatively easily through contact with contaminated farming equipment, vehicles, clothing, and feed, and by domestic and wild predators. Its containment demands considerable efforts in vaccination, strict monitoring, trade restrictions, quarantines, and the culling of both infected and healthy (uninfected) animals. Susceptible animals include cattle, water buffalo, sheep, goats, pigs, antelope, deer, and bison. It has also been known to infect hedgehogs and elephants; llamas and alpacas may develop mild symptoms, but are res ...
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Herd Immunity
Herd immunity (also called herd effect, community immunity, population immunity, or mass immunity) is a form of indirect protection that applies only to contagious diseases. It occurs when a sufficient percentage of a population has become immune to an infection, whether through previous infections or vaccination, thereby reducing the likelihood of infection for individuals who lack immunity. Once the herd immunity has been reached, disease gradually disappears from a population and may result in eradication or permanent reduction of infections to zero if achieved worldwide. Herd immunity created via vaccination has contributed to the reduction of many diseases. Effects Protection of those without immunity Some individuals either cannot develop immunity after vaccination or for medical reasons cannot be vaccinated. Newborn infants are too young to receive many vaccines, either for safety reasons or because passive immunity renders the vaccine ineffective. Individuals who ...
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Horse Diseases
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolution of the horse, evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication of the horse, domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from equine anatomy, anatomy to life stages, size, equine coat color, colors, horse markings, markings, horse breed, ...
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Animal Viral Diseases
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echi ...
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