Epidemiology Of Breast Cancer
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Epidemiology Of Breast Cancer
Worldwide, breast cancer is the most common invasive cancer in women.The most common form of cancer is non-invasive non-melanoma skin cancer; non-invasive cancers are generally easily cured, cause very few deaths, and are routinely excluded from cancer statistics. Breast cancer comprises 22.9% of invasive cancers in women and 16% of all female cancers. In 2008, breast cancer caused 458,503 deaths worldwide, which is 13.7% of cancer deaths in women and 6.0% of all cancer deaths for men and women together.(cancer statistics often exclude non-melanoma skin cancers such as basal cell carcinoma which though very common are rarely fatal) Lung cancer, the second most common cause of cancer-related death in women, caused 12.8% of cancer deaths in women, which is 18.2% of all cancer deaths for men and women together. The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. By age group Breast cancer is strongly r ...
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Breast Cancer World Map - Death - WHO2004
The breast is one of two prominences located on the upper ventral region of a primate's torso. Both females and males develop breasts from the same embryological tissues. In females, it serves as the mammary gland, which produces and secretes milk to feed infants. Subcutaneous fat covers and envelops a network of ducts that converge on the nipple, and these tissues give the breast its size and shape. At the ends of the ducts are lobules, or clusters of alveoli, where milk is produced and stored in response to hormonal signals. During pregnancy, the breast responds to a complex interaction of hormones, including estrogens, progesterone, and prolactin, that mediate the completion of its development, namely lobuloalveolar maturation, in preparation of lactation and breastfeeding. Humans are the only animals with permanent breasts. At puberty, estrogens, in conjunction with growth hormone, cause permanent breast growth in female humans. This happens only to a much lesser e ...
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Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ...
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Skin Neoplasm
Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC). Basal-cell cancer grows slowly and can damage the tissue around it but is unlikely to spread to distant areas or result in death. It often appears as a painless raised area of skin that may be shiny with small blood vessels running over it or may present as a raised area with an ulcer. Squamous-cell skin cancer is more likely to spread. It usually presents as a hard lump with a scaly top but may also form an ulcer. Melanomas are the most aggressive. Signs include a mole that has changed in size, shape, color, has irregular edges, has more than one color, is itchy or bleeds. More tha ...
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International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; french: Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also collects and publishes surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were the Federal Republic of Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 27 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de la Vignerie relating his story, and urging support for the creation of an intern ...
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Basal Cell Carcinoma
Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raised area with ulceration. Basal-cell cancer grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in death. Risk factors include exposure to ultraviolet light, having lighter skin, radiation therapy, long-term exposure to arsenic and poor immune-system function. Exposure to UV light during childhood is particularly harmful. Tanning beds have become another common source of ultraviolet radiation. Diagnosis often depends on skin examination, confirmed by tissue biopsy. It remains unclear whether sunscreen affects the risk of basal-cell cancer. Treatment is typically by surgical removal. This can be by simple excision if the cancer is small; otherwise, Mohs surgery is generally recomme ...
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Lung Cancer
Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from transformed, malignant cells that originate as epithelial cells, or from tissues composed of epithelial cells. Other lung cancers, such as the rare sarcomas of the lung, are generated by the malignant transformation of connective tissues (i.e. nerve, fat, muscle, bone), which arise from mesenchymal cells. Lymphomas and melanomas (from lymphoid and melanocyte cell lineages) can also rarely result in lung cancer. In time, this uncontrolled neoplasm, growth can metastasis, metastasize (spreading beyond the lung) either by direct extension, by entering the lymphatic circulation, or via hematogenous, bloodborne spread – into nearby tissue or other, more distant parts of the body. Most cancers that originate from within the lungs, known as primary ...
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The Independent
''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was published on Saturday 26 March 2016, leaving only the online edition. The newspaper was controlled by Tony O'Reilly's Irish Independent News & Media from 1997 until it was sold to the Russian oligarch and former KGB Officer Alexander Lebedev in 2010. In 2017, Sultan Muhammad Abuljadayel bought a 30% stake in it. The daily edition was named National Newspaper of the Year at the 2004 British Press Awards. The website and mobile app had a combined monthly reach of 19,826,000 in 2021. History 1986 to 1990 Launched in 1986, the first issue of ''The Independent'' was published on 7 October in broadsheet format.Dennis Griffiths (ed.) ''The Encyclopedia of the British Press, 1422–1992'', London & Basingstoke: Macmillan, 1992, p. 330 It was produc ...
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Incidence Rate
In epidemiology, incidence is a measure of the probability of occurrence of a given medical condition in a population within a specified period of time. Although sometimes loosely expressed simply as the number of new cases during some time period, it is better expressed as a proportion or a rate with a denominator. Incidence proportion Incidence proportion (IP), also known as cumulative incidence, is defined as the probability that a particular event, such as occurrence of a particular disease, has occurred before a given time. It is calculated dividing the number of new cases during a given period by the number of subjects at risk in the population initially at risk at the beginning of the study. Where the period of time considered is an entire lifetime, the incidence proportion is called lifetime risk. For example, if a population initially contains 1,000 persons and 28 develop a condition since the disease first occurred until two years later, the cumulative incidence prop ...
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Most Common Cancers - Female, By Occurence
Most or Möst or ''variation'', may refer to: Places * Most, Kardzhali Province, a village in Bulgaria * Most (city), a city in the Czech Republic ** Most District, a district surrounding the city ** Most Basin, a lowland named after the city ** Autodrom Most, motorsport race track near Most * Möst, Khovd, a district in Khovd, Mongolia * Most, Mokronog-Trebelno, a settlement in Slovenia Other uses * Most (surname), including a list of people with the surname * Franz Welser-Möst (born 1960), Austrian conductor * ''Most'' (1969 film), a film about WWII Yugoslavian partisans * ''Most'' (2003 film), a Czech film * '' Most!'', 2018 Czech TV series * Most (grape) or Chasselas * most (Unix), a terminal pager on Unix and Unix-like systems * Most (wine) or Apfelwein * ''most'', an English degree determiner * Monolithic System Technology (MoST), a defunct American fabless semiconductor company See also * MOST (other) * The Most (other) * Must (other) * Moest ...
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Most Common Cancers - Female, By Mortality
Most or Möst or ''variation'', may refer to: Places * Most, Kardzhali Province, a village in Bulgaria * Most (city), a city in the Czech Republic ** Most District, a district surrounding the city ** Most Basin, a lowland named after the city ** Autodrom Most, motorsport race track near Most * Möst, Khovd, a district in Khovd, Mongolia * Most, Mokronog-Trebelno, a settlement in Slovenia Other uses * Most (surname), including a list of people with the surname * Franz Welser-Möst (born 1960), Austrian conductor * ''Most'' (1969 film), a film about WWII Yugoslavian partisans * ''Most'' (2003 film), a Czech film * '' Most!'', 2018 Czech TV series * Most (grape) or Chasselas * most (Unix), a terminal pager on Unix and Unix-like systems * Most (wine) or Apfelwein * ''most'', an English degree determiner * Monolithic System Technology (MoST), a defunct American fabless semiconductor company See also * MOST (other) * The Most (other) * Must (other) * Moest ...
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Age Adjustment
In epidemiology and demography, age adjustment, also called age standardization, is a technique used to allow statistical populations to be compared when the age profiles of the populations are quite different. Example For example, in 2004/5, two Australian health surveys investigated rates of long-term circulatory system health problems (e.g. heart disease) in the general Australian population, and specifically in the Indigenous Australian population. In each age category over age 24, Indigenous Australians had markedly higher rates of circulatory disease than the general population: 5% vs 2% in age group 25–34, 12% vs 4% in age group 35–44, 22% vs 14% in age group 45–54, and 42% vs 33% in age group 55+. However, overall, these surveys estimated that 12% of all Indigenous Australians had long-term circulatory problems compared to 18% of the overall Australian population. To understand this "apparent contradiction", we note that this only includes age groups over 24 and igno ...
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Heart Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximatel ...
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