Enterobacter Sakazakii
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Enterobacter Sakazakii
''Cronobacter sakazakii'', which before 2007 was named ''Enterobacter sakazakii'', is an opportunistic Gram-negative, bacillus, rod-shaped, pathogenic bacteria, bacterium that can live in very dry places, otherwise known as xerotolerance. ''C. sakazakii'' utilizes a number of genes to survive desiccation and this xerotolerance may be strain specific. The majority of ''C. sakazakii'' cases are adults but low-birth-weight preterm neonatal and older infants are at the highest risk. The pathogen is a rare cause of invasive infection in infants, with historically high case fatality rates (40–80%). In infants it can cause bacteraemia, meningitis and necrotising enterocolitis, necrotizing enterocolitis. Most neonatal ''C. sakazakii'' infections cases have been associated with the use of powdered infant formula with some strains able to survive in a desiccated state for more than two years. However, not all cases have been linked to contaminated infant formula. In November 2011, several ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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