Emma Louise Call
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Emma Louise Call
Emma Louise Call (1847–1937) was an American physician, and one of the first female physicians in the United States. Along with Sigmund Exner, she is one of the namesakes of Call-Exner bodies, a pathognomonic feature of granulosa cell tumors. These tumors are associated with ovarian cancers. Biography Call received her MD from the University of Michigan Medical School in 1873, and moved to Vienna as Sigmund Exner's postgraduate student. In 1875, they published the manuscript announcing their findings of the pathology findings - eosinophilic follicles present in ovarian tumors - that would later be named after the two of them. This would be Call's only publication, as she later returned to Boston and practiced clinically as an obstetrician for 40 years. Call would become the first woman to receive membership into the Massachusetts Medical Society in 1884. "I entered the Medical Department of the University the first year that women were admitted. The first class of women...were ...
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Sigmund Exner
Sigmund Exner (also ''Sigmund Exner'', ''Siegmund Exner-Ewarten'', ''Siegmund Exner Ritter von Ewarten''; 5 April 1846 – 5 February 1926) was an Austrian physiologist born in Vienna. Academic career He studied in Vienna under Ernst Wilhelm von Brücke (1819–1892), and in Heidelberg with Hermann von Helmholtz (1821–1894). In 1870 he received his degree, subsequently working as an assistant in the physiological institute at the University of Vienna. In 1891 he succeeded Ernst von Brücke as professor of physiology and director of the physiological institute. During his career, he received honorary doctorates from the Universities of Leipzig and Athens. Physiological research Sigmund Exner is known for his work in comparative physiology, and his studies of perception psychology from a physiological standpoint. He conducted important research on localization of behavioral functionality in the brain, in particular studies on the functional architecture of the visual cortex ...
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Pathognomonic
Pathognomonic (rare synonym ''pathognomic'') is a term, often used in medicine, that means "characteristic for a particular disease". A pathognomonic sign is a particular sign whose presence means that a particular disease is present beyond any doubt. Labelling a sign or symptom "pathognomonic" represents a marked intensification of a "diagnostic" sign or symptom. The word is an adjective of Greek origin derived from πάθος ''pathos'' "disease" and γνώμων ''gnomon'' "indicator" (from γιγνώσκω ''gignosko'' "I know, I recognize"). Practical use While some findings may be classic, typical or highly suggestive in a certain condition, they may not occur ''uniquely'' in this condition and therefore may not directly imply a specific diagnosis. A pathognomonic sign or symptom has very high positive predictive value but does not need to have high sensitivity: for example it can sometimes be absent in a certain disease, since the term only implies that, when it is prese ...
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Granulosa Cell Tumor
Granulosa cell tumours are tumours that arise from granulosa cells. They are estrogen secreting tumours and present as large, complex, ovarian masses. These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours. Although granulosa cells normally occur only in the ovary, granulosa cell tumours occur in both ovaries and testicles (see ovarian cancer and testicular cancer). These tumours should be considered malignant and treated in the same way as other malignant tumours of ovary. The ovarian disease has two forms, juvenile and adult, both characterized by indolent growth, and therefore has high recovery rates. The staging system for these tumours is the same as for epithelial tumours and most present as stage I.Gynaecology. 3rd Ed. 2003. Churchill Livingstone, pp. 690-691. The peak age at which they occur is 50–55 years, but they may occur at any age. Juvenile granulosa cell tumour is a similar but distinct rare tumour. It too occurs in both ...
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Ovarian Cancer
Ovarian cancer is a cancerous tumor of an ovary. It may originate from the ovary itself or more commonly from communicating nearby structures such as fallopian tubes or the inner lining of the abdomen. The ovary is made up of three different cell types including epithelial cells, germ cells, and stromal cells. When these cells become abnormal, they have the ability to divide and form tumors. These cells can also invade or spread to other parts of the body. When this process begins, there may be no or only vague symptoms. Symptoms become more noticeable as the cancer progresses. These symptoms may include bloating, vaginal bleeding, pelvic pain, abdominal swelling, constipation, and loss of appetite, among others. Common areas to which the cancer may spread include the lining of the abdomen, lymph nodes, lungs, and liver. The risk of ovarian cancer increases with age. Most cases of ovarian cancer develop after menopause. It is also more common in women who have ovulated m ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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University Of Michigan Medical School
Michigan Medicine (University of Michigan Health System or UMHS before 2017) is the wholly owned academic medical center of the University of Michigan, a public research university in Ann Arbor, Michigan. Michigan Medicine includes the University of Michigan Medical School, with its faculty group practice and research laboratories; the university's affiliated hospitals and health centers, including the University of Michigan Hospital, C.S. Mott Children's Hospital, Von Voigtlander Women's Hospital, and approximately 40 health centers and home care services across southeast Michigan; the clinical programs of the University of Michigan School of Nursing; and the activities of the Michigan Health Corporation, through which U-M partners with other medical centers and hospitals to provide specialized care throughout Michigan. History In 1869 the University of Michigan opened the first hospital in the country owned and operated by a university, in a house in Ann Arbor originally b ...
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Vienna, Austria
en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST = CEST , utc_offset_DST = +2 , blank_name = Vehicle registration , blank_info = W , blank1_name = GDP , blank1_info = € 96.5 billion (2020) , blank2_name = GDP per capita , blank2_info = € 50,400 (2020) , blank_name_sec1 = HDI (2019) , blank_info_sec1 = 0.947 · 1st of 9 , blank3_name = Seats in the Federal Council , blank3_info = , blank_name_sec2 = GeoTLD , blank_info_sec2 = .wien , website = , footnotes = , image_blank_emblem = Wien logo.svg , blank_emblem_size = Vienna ( ; german: Wien ; bar ...
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Eosinophil
Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells (WBCs) and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. They form about 2 to 3% of WBCs. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such ...
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Elizabeth Blackwell
Elizabeth Blackwell (3 February 182131 May 1910) was a British physician, notable as the first woman to receive a medical degree in the United States, and the first woman on the Medical Register of the General Medical Council for the United Kingdom. Blackwell played an important role in both the United States and the United Kingdom as a social awareness and moral reformer, and pioneered in promoting education for women in medicine. Her contributions remain celebrated with the Elizabeth Blackwell Medal, awarded annually to a woman who has made a significant contribution to the promotion of women in medicine. Blackwell was initially uninterested in a career in medicine, especially after her schoolteacher brought in a bull's eye to use as a teaching tool for studying the anatomy enabling vision. Therefore, she became a schoolteacher in order to support her family. This occupation was seen as suitable for women during the 1800s; however, she soon found it unsuitable for her. Blackw ...
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1847 Births
Events January–March * January 4 – Samuel Colt sells his first revolver pistol to the U.S. government. * January 13 – The Treaty of Cahuenga ends fighting in the Mexican–American War in California. * January 16 – John C. Frémont is appointed Governor of the new California Territory. * January 17 – St. Anthony Hall fraternity is founded at Columbia University, New York City. * January 30 – Yerba Buena, California, is renamed San Francisco. * February 5 – A rescue effort, called the First Relief, leaves Johnson's Ranch to save the ill-fated Donner Party (California-bound emigrants who became snowbound in the Sierra Nevada earlier this winter; some have resorted to survival by cannibalism). * February 22 – Mexican–American War: Battle of Buena Vista – 5,000 American troops under General Zachary Taylor use their superiority in artillery to drive off 15,000 Mexican troops under Antonio López de Santa Anna, defeating the Mexicans the next da ...
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