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Emaciation
Emaciation is defined as the state of extreme thinness from absence of body fat and muscle wasting usually resulting from malnutrition. Characteristics In humans, the physical appearance of emaciation includes thinned limbs, pronounced and protruding bones, sunken eyes, dry skin, thinning hair, a bloated stomach, and a dry or coated tongue. Emaciation is often accompanied by halitosis, hyponatremia, hypokalemia, anemia, improper function of lymph and the lymphatic system, and pleurisy and edema. Causes Emaciation can be caused by undernutrition, malaria and cholera, tuberculosis and other infectious diseases with prolonged fever, parasitic infections, many forms of cancer and their treatments, lead poisoning, and eating disorders like anorexia nervosa. Emaciation is widespread in least developed countries and was a major cause of death in Nazi concentration camps during World War II. Animals A lack of resources in the habitat, disease, or neglect and cruelty from humans ...
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Marasmus
Marasmus is a form of severe malnutrition characterized by energy deficiency. It can occur in anyone with severe malnutrition but usually occurs in children. Body weight is reduced to less than 62% of the normal (expected) body weight for the age. Marasmus occurrence increases prior to age 1, whereas kwashiorkor occurrence increases after 18 months. It can be distinguished from kwashiorkor in that kwashiorkor is protein deficiency with adequate energy intake whereas marasmus is inadequate energy intake in all forms, including protein. This clear-cut separation of marasmus and kwashiorkor is however not always clinically evident as kwashiorkor is often seen in a context of insufficient caloric intake, and mixed clinical pictures, called marasmic kwashiorkor, are possible. Protein wasting in kwashiorkor generally leads to edema and ascites, while muscular wasting and loss of subcutaneous fat are the main clinical signs of marasmus, which makes the ribs and joints protrude. Th ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of ac ...
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Cachexia
Cachexia () is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation. A range of diseases can cause cachexia, most commonly cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS. Systemic inflammation from these conditions can cause detrimental changes to metabolism and body composition. In contrast to weight loss from inadequate caloric intake, cachexia causes mostly muscle loss instead of fat loss. Diagnosis of cachexia can be difficult due to the lack of well-established diagnostic criteria. Cachexia can improve with treatment of the underlying illness but other treatment approaches have limited benefit. Cachexia is associated with increased mortality and poor quality of life. The term is from Greek κακός ''kakos'', "bad", and ἕξις ''hexis'', "condition". Causes Cachexia can be caused by diverse medical conditions, but is ...
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Gong Kai, Emaciated Horse
A gongFrom Indonesian and ms, gong; jv, ꦒꦺꦴꦁ ; zh, c=鑼, p=luó; ja, , dora; km, គង ; th, ฆ้อง ; vi, cồng chiêng; as, কাঁহ is a percussion instrument originating in East Asia and Southeast Asia. Gongs are a flat, circular metal disc that is typically struck with a mallet. They can be small or large in size, and tuned or can require tuning. The earliest mention of gongs can be found in sixth century Chinese records, which mentioned the instrument to have come from a country between Tibet and Burma. The term ''gong'' ( jv, ꦒꦺꦴꦁ) originated in the Indonesian island of Java. Scientific and archaeological research has established that Burma, China, Java and Annam were the four main gong manufacturing centres of the ancient world. The gong found its way into the Western World in the 18th century, when it was also used in the percussion section of a Western-style symphony orchestra. A form of bronze cauldron gong known as a restin ...
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World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies of World War II, Allies and the Axis powers. World War II was a total war that directly involved more than 100 million Military personnel, personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Air warfare of World War II, Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the Atomic bombings of Hiroshima and Nagasaki, only two nuclear weapons ever used in war. World War II was by far the List of wars by death toll, deadliest conflict in hu ...
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Nazi Concentration Camps
From 1933 to 1945, Nazi Germany operated more than a thousand concentration camps, (officially) or (more commonly). The Nazi concentration camps are distinguished from other types of Nazi camps such as forced-labor camps, as well as concentration camps operated by Germany's allies. on its own territory and in parts of German-occupied Europe. The first camps were established in March 1933 immediately after Adolf Hitler became Chancellor of Germany. Following the 1934 purge of the SA, the concentration camps were run exclusively by the SS via the Concentration Camps Inspectorate and later the SS Main Economic and Administrative Office. Initially, most prisoners were members of the Communist Party of Germany, but as time went on different groups were arrested, including "habitual criminals", "asocials", and Jews. After the beginning of World War II, people from German-occupied Europe were imprisoned in the concentration camps. Following Allied military victories, ...
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Anorexia Nervosa
Anorexia nervosa, often referred to simply as anorexia, is an eating disorder characterized by low weight, food restriction, body image disturbance, fear of gaining weight, and an overpowering desire to be thin. ''Anorexia'' is a term of Greek origin: ''an-'' (ἀν-, prefix denoting negation) and ''orexis'' (ὄρεξις, "appetite"), translating literally to "a loss of appetite"; the adjective ''nervosa'' indicating the functional and non-organic nature of the disorder. ''Anorexia nervosa'' was coined by Gull in 1873 but, despite literal translation, the feeling of hunger is frequently present and the pathological control of this instinct is a source of satisfaction for the patients. Individuals with anorexia nervosa have a fear of being overweight or being seen as such, although they are in fact underweight. The DSM-5 describes this perceptual symptom as "disturbance in the way in which one's body weight or shape is experienced". In research and clinical settings, thi ...
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Eating Disorder
An eating disorder is a mental disorder defined by abnormal eating behaviors that negatively affect a person's physical or mental health. Only one eating disorder can be diagnosed at a given time. Types of eating disorders include binge eating disorder, where the patient eats a large amount in a short period of time; anorexia nervosa, where the person has an intense fear of gaining weight and restricts food or overexercises to manage this fear; bulimia nervosa, where individuals eat a large quantity (binging) then try to rid themselves of the food (purging); pica, where the patient eats non-food items; rumination syndrome, where the patient regurgitates undigested or minimally digested food; avoidant/restrictive food intake disorder (ARFID), where people have a reduced or selective food intake due to some psychological reasons (see below); and a group of other specified feeding or eating disorders. Anxiety disorders, depression and substance abuse are common among people wit ...
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Lead Poisoning
Lead poisoning, also known as plumbism and saturnism, is a type of metal poisoning caused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, infertility, and tingling in the hands and feet. It causes almost 10% of intellectual disability of otherwise unknown cause and can result in behavioral problems. Some of the effects are permanent. In severe cases, anemia, seizures, coma, or death may occur. Exposure to lead can occur by contaminated air, water, dust, food, or consumer products. Lead poisoning poses a significantly increased risk to children as they are far more likely to ingest lead indirectly by chewing on toys or other objects that are coated in lead paint. The amount of lead that can be absorbed by children is also higher than that of adults. Exposure at work is a common cause of lead poisoning in adults with certain occupations at particular risk. Diagnosis is typically by ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals ( signal transduction). The development of therapies with specific molecular or genetic tar ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes ...
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