Eledoisin
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Eledoisin
Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides. It was first isolated from the posterior salivary glands of two mollusk species ''Eledone muschata'' and ''Eledone aldovandi'', which belong to the octopod order of Cephalopoda.De Marco, A., and G. Gatti, "1H- and 13C-NMR spectra of eledoisin and intermediate oligopeptides." ''Int. J. Pep. Pro. Res.'' 7:437–444, 1975. Other tachykinins from nonmammalian sources include kassinin and physalaemin. The mammalian tachykinins substance P, NKA, and NKB have similar effects as tachykinins of nonmammals and have been more widely studied and characterized. These peptides exhibit a wide and complex spectrum of pharmacological and physiological activities such as vasodilation, hypertension, and stimulation of extravascular smooth muscle.R. Christy Rani Grace, Indu R. Chandrashekar and Sudha M. Cowsik"Solution Structure of the Tachykinin Peptide Eledoisin", ''Biophysical Journal'' 84:6 ...
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