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Eileen Saxon
Eileen Saxon, sometimes referred to as "The Blue Baby", was the patient in an operation that ushered in the modern era of cardiac surgery. She had a condition called Tetralogy of Fallot, one of the primary congenital defects that lead to blue baby syndrome. In this condition, defects in the great vessels and wall of the heart lead to a chronic lack of oxygen in the blood. In Eileen's case, this made her lips and fingers turn blue, with the rest of her skin having a very faint blue tinge. She could only take a few steps before beginning to breathe heavily. On November 29, 1944, Saxon was the first living human to receive a groundbreaking operation. (now known as a Blalock-Thomas-Taussig shunt) suggested by pediatric cardiologist Helen B. Taussig and administered by Alfred Blalock, with Vivien Thomas, who had perfected the surgery in laboratory tests on animals, standing over his shoulder to advise him on performing the surgery. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetralogy Of Fallot
Tetralogy of Fallot (TOF), formerly known as Steno-Fallot tetralogy, is a congenital heart defect characterized by four specific cardiac defects. Classically, the four defects are: *pulmonary stenosis, which is narrowing of the exit from the right ventricle; * a ventricular septal defect, which is a hole allowing blood to flow between the two ventricles; * right ventricular hypertrophy, which is thickening of the right ventricular muscle; and * an overriding aorta, which is where the aorta expands to allow blood from both ventricles to enter. At birth, children may be asymptomatic or present with many severe symptoms. Later in infancy, there are typically episodes of bluish colour to the skin due to a lack of sufficient oxygenation, known as cyanosis. When affected babies cry or have a bowel movement, they may undergo a "tet spell" where they turn cyanotic, have difficulty breathing, become limp, and occasionally lose consciousness. Other symptoms may include a heart murmur, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blue Baby Syndrome
Blue baby syndrome can refer to conditions that cause cyanosis, or blueness of the skin, in babies as a result of low oxygen levels in the blood. This term has traditionally been applied to cyanosis as a result of: #Cyanotic heart disease, which is a category of congenital heart defect that results in low levels of oxygen in the blood. This can be caused by either reduced blood flow to the lungs or mixing of oxygenated and deoxygenated blood. # Methemoglobinemia, which is a disease defined by high levels of methemoglobin in the blood. Increased levels of methemoglobin prevent oxygen from being released into the tissues and result in hypoxemia. Although these are the most common causes of cyanosis, there are other potential factors that can cause a blue tint to a baby's skin or mucous membranes. These factors include hypoventilation, perfusion or ventilation differences in the lungs, and poor cardiac output of oxygenated blood, among others. The blue baby syndrome or cyanosis occ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygen
Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as well as with other compounds. Oxygen is Earth's most abundant element, and after hydrogen and helium, it is the third-most abundant element in the universe. At standard temperature and pressure, two atoms of the element bind to form dioxygen, a colorless and odorless diatomic gas with the formula . Diatomic oxygen gas currently constitutes 20.95% of the Earth's atmosphere, though this has changed considerably over long periods of time. Oxygen makes up almost half of the Earth's crust in the form of oxides.Atkins, P.; Jones, L.; Laverman, L. (2016).''Chemical Principles'', 7th edition. Freeman. Many major classes of organic molecules in living organisms contain oxygen atoms, such as proteins, nucleic acids, carbohydrates, and fats, as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pediatrics
Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the age of 18. The American Academy of Pediatrics recommends people seek pediatric care through the age of 21, but some pediatric subspecialists continue to care for adults up to 25. Worldwide age limits of pediatrics have been trending upward year after year. A medical doctor who specializes in this area is known as a pediatrician, or paediatrician. The word ''pediatrics'' and its cognates mean "healer of children," derived from the two Greek words: (''pais'' "child") and (''iatros'' "doctor, healer"). Pediatricians work in clinics, research centers, universities, general hospitals and children's hospitals, including those who practice pediatric subspecialties (e.g. neonatology requires resources available in a NICU). History The ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiologist
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat adult heart disease. Surgical aspects are not included in car ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helen B
Helen may refer to: People * Helen of Troy, in Greek mythology, the most beautiful woman in the world * Helen (actress) (born 1938), Indian actress * Helen (given name), a given name (including a list of people with the name) Places * Helen, Georgia, United States, a small city * Helen, Maryland, United States, an unincorporated place * Helen, Washington, an unincorporated community in Washington state, US * Helen, West Virginia, a census-designated place in Raleigh County * Helen Falls, a waterfall in Ontario, Canada * Lake Helen (other), several places called Helen Lake or Lake Helen * Helen, an ancient name of Makronisos island, Greece * The Hellenic Republic, Greece Arts, entertainment, and media * ''Helen'' (album), a 1981 Grammy-nominated album by Helen Humes * ''Helen'' (2008 film), a British drama starring Annie Townsend * ''Helen'' (2009 film), an American drama film starring Ashley Judd * ''Helen'' (2017 film), an Iranian drama film * ''Helen'' (2019 fil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred Blalock
Alfred Blalock (April 5, 1899 – September 15, 1964) was an American surgeon most noted for his work on the medical condition of shock as well as Tetralogy of Fallot— commonly known as Blue baby syndrome. He created, with assistance from his research and laboratory assistant Vivien Thomas and pediatric cardiologist Helen Taussig, the Blalock-Thomas-Taussig Shunt, a surgical procedure to relieve the cyanosis from Tetralogy of Fallot. This operation ushered in the modern era of cardiac surgery. He worked at both Vanderbilt University and Johns Hopkins University, where he studied medicine and later served as chief of surgery. He is known as a medical pioneer who won various awards, including Albert Lasker Clinical Medical Research Award. Blalock was also nominated several times for the prestigious Nobel Prize in Medicine. Early life and education Blalock was born in Culloden, Georgia, the son of Martha "Mattie" (Davis) and George Zadock Blalock, a merchant. At the age of 14, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vivien Thomas
Vivien Theodore Thomas (August 29, 1910 – November 26, 1985) was an American laboratory supervisor who developed a procedure used to treat blue baby syndrome (now known as cyanotic heart disease) in the 1940s. He was the assistant to surgeon Alfred Blalock in Blalock's experimental animal laboratory at Vanderbilt University in Nashville, Tennessee, and later at the Johns Hopkins University in Baltimore, Maryland. Thomas was unique in that he did not have any professional education or experience in a research laboratory; however, he served as supervisor of the surgical laboratories at Johns Hopkins for 35 years. In 1976, Hopkins awarded him an honorary doctorate and named him an instructor of surgery for the Johns Hopkins School of Medicine. Without any education past high school, Thomas rose above poverty and racism to become a cardiac surgery pioneer and a teacher of operative techniques to many of the country's most prominent surgeons. A PBS documentary, ''Partners of the Hea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyanosis
Cyanosis is the change of body tissue color to a bluish-purple hue as a result of having decreased amounts of oxygen bound to the hemoglobin in the red blood cells of the capillary bed. Body tissues that show cyanosis are usually in locations where the skin is thinner, including the mucous membranes, lips, nail beds, and ear lobes. Some medications containing amiodarone or silver, Mongolian spots, large birth marks, and the consumption of food products with blue or purple dyes can also result in the bluish skin tissue discoloration and may be mistaken for cyanosis. Cyanosis is further classified into central cyanosis vs. peripheral cyanosis. Pathophysiology The mechanism behind cyanosis is different depending on whether it is central or peripheral. Central cyanosis Central cyanosis is caused by a decrease in arterial oxygen saturation (SaO2) and begins to show once the concentration of deoxyhemoglobin in the blood reaches a concentration of ≥ 5.0 g/dL (≥ 3.1 mmol/L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Something The Lord Made
''Something the Lord Made'' is a 2004 American television film, made-for-television biographical film, biographical drama (film and television), drama film about the black cardiac pioneer Vivien Thomas (1910–1985) and his complex and volatile partnership with white surgeon Alfred Blalock (1899–1964), the "Blue Baby doctor" who pioneered modern heart surgery. Based on the National Magazine Award-winning ''Washingtonian (magazine), Washingtonian'' magazine article "Like Something the Lord Made" by Katie McCabe, the film was directed by Joseph Sargent and written by Peter Silverman and Robert Caswell. Plot summary ''Something the Lord Made'' tells the story of the 34-year partnership that begins in Depression Era Nashville, Tennessee, Nashville in 1930 when Blalock (Alan Rickman) hires Thomas (Mos Def) as an assistant at his Vanderbilt University lab, expecting him to perform janitorial work. But Thomas' remarkable manual dexterity and intellectual acumen confound Blalock's expect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1942 Births
Year 194 ( CXCIV) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Septimius and Septimius (or, less frequently, year 947 ''Ab urbe condita''). The denomination 194 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus and Decimus Clodius Septimius Albinus Caesar become Roman Consuls. * Battle of Issus: Septimius Severus marches with his army (12 legions) to Cilicia, and defeats Pescennius Niger, Roman governor of Syria. Pescennius retreats to Antioch, and is executed by Severus' troops. * Septimius Severus besieges Byzantium (194–196); the city walls suffer extensive damage. Asia * Battle of Yan Province: Warlords Cao Cao and Lü Bu fight for control over Yan Province; the battle lasts for over 100 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
