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Ehrlichia Wisconsin HM543746
''Ehrlichia'' Wisconsin HM543746 is an unnamed tick bacterium that spread through Minnesota and Wisconsin in 2009 and is similar to ''Ehrlichia muris''. Researchers took more than 4000 blood samples from people who appeared to have ehrlichiosis or anaplasmosis, and used 697 ticks from both states as test subjects. The researchers, working at the Mayo Clinic, used molecular methods, culturing, and serological testing. The research was conducted after technologist Carol Werner noticed an unnatural Ehrlichia polymerase chain reaction result. The investigation arrived at the discovery of the new bacterium because the research showed that four of the patients were infected by a new bacterium; their symptoms in 2009 including fevers, headaches, fatigue, nausea, and vomiting. All four of the patients survived by being treated with doxycycline. The results were published in ''The New England Journal of Medicine'' and brought up in a Health Alert Network public health announcement. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tick
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are from the Cretaceous period, around 100 million years old. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families, the Ixodidae or hard ticks, and the Argasidae, or soft ticks. ''Nuttalliella,'' a genus of tick from southern Africa is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalothorax and abdomen are completely fused. In addit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. History In September 1811, John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' purchased the weekly ''Intelligencer'' for $600 in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ehrlichia Ewingii
''Ehrlichia ewingii'' is a species of rickettsiales bacteria. It has recently been associated with human infection, and can be detected via PCR serological testing. The name ''Ehrlichia ewingii'' was proposed in 1992. Taxonomy and characterization Taxonomy The current classification is Bacteria, Pseudomonadota, Alphaproteobacteria, Rickettsiales, Anaplasmataceae, ''Ehrlichia ewingii''. Classification of different members of the genus ''Ehrlichia'' has been disputed, however, it is generally agreed that close relatives of ''Ehrlichia ewingii'' are ''Ehrlichia chaffeensis'' and ''Ehrlichia canis''. It is also closely related to ''Wolbachia'', ''Anaplasma'', and '' Neorickettsia'' bacteria, with ''Rickettsia'' as a more distant genus. Characterization Species in the family Anaplasmataceae have unique characteristics that can help differentiate them from other families including: sensitivity to mechanical stress, changes in osmolarity, and thawing. &n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ehrlichia Chaffeensis
''Ehrlichia chaffeensis'' is an obligate intracellular, Gram-negative species of Rickettsiales bacteria. It is a zoonotic pathogen transmitted to humans by the Amblyomma americanum, lone star tick (''Amblyomma americanum''). It is the causative agent of human monocytic ehrlichiosis. Genetic studies support the endosymbiotic theory that a subset of these organisms evolved to live inside mammalian cells as mitochondria to provide cellular energy to the cells in return for protection and sustenance. ATP production in the rickettsiae is biochemically identical to that in mammalian mitochondria; all multi-cellular eukaryotes have mitochondria in their cells, including birds, fish, reptiles, invertebrates, plants, and fungi in addition to mammals. Human monocytic ehrlichiosis caused by ''E. chaffeensis'' is known to spread through tick infection primarily in the Southern, South-central and Mid-Atlantic regions of the United States. In recent years, the lone star tick has expanded i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ixodes Scapularis
''Ixodes scapularis'' is commonly known as the deer tick or black-legged tick (although some people reserve the latter term for ''Ixodes pacificus'', which is found on the west coast of the US), and in some parts of the US as the bear tick. It was also named ''Ixodes dammini'' until it was shown to be the same species in 1993. It is a hard-bodied tick found in the eastern and northern Midwest of the United States as well as in southeastern Canada. It is a vector for several diseases of animals, including humans (Lyme disease, babesiosis, anaplasmosis, Powassan virus disease, etc.) and is known as the deer tick owing to its habit of parasitizing the white-tailed deer. It is also known to parasitize mice, lizards, migratory birds, etc. especially while the tick is in the larval or nymphal stage. Description The image shown here—and in fact, most images of ''Ixodes scapularis'' that are commonly available—show an adult female that is unengorged, that is, an adult female that h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Entomologist
Entomology () is the scientific study of insects, a branch of zoology. In the past the term "insect" was less specific, and historically the definition of entomology would also include the study of animals in other arthropod groups, such as arachnids, myriapods, and crustaceans. This wider meaning may still be encountered in informal use. Like several of the other fields that are categorized within zoology, entomology is a taxon-based category; any form of scientific study in which there is a focus on insect-related inquiries is, by definition, entomology. Entomology therefore overlaps with a cross-section of topics as diverse as molecular genetics, behavior, neuroscience, biomechanics, biochemistry, systematics, physiology, developmental biology, ecology, morphology, and paleontology. Over 1.3 million insect species have been described, more than two-thirds of all known species. Some insect species date back to around 400 million years ago. They have many kinds of intera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doxycycline
Doxycycline is a broad-spectrum tetracycline class antibiotic used in the treatment of infections caused by bacteria and certain parasites. It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. It is also used to prevent malaria in combination with quinine. Doxycycline may be taken by mouth or by injection into a vein. Common side effects include diarrhea, nausea, vomiting, abdominal pain, and an increased risk of sunburn. Use during pregnancy is not recommended. Like other agents of the tetracycline class, it either slows or kills bacteria by inhibiting protein production. It kills malaria by targeting a plastid organelle, the apicoplast. Doxycycline was patented in 1957 and came into commercial use in 1967. It is on the World Health Organization's List of Essential Medicines. Doxycycline is available as a generic medicine. In 2020, it was the 79th most commonly prescribed medication in the United States, with m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. While not painful, it can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat. Over 30 definitions of nausea were proposed in a 2011 book on the topic. Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are gastroenteritis and other gastrointestinal disorders, food poisoning, motion sickness, dizziness, migraine, fainting, low blood sugar, anxiety, and lack of sleep. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by disgust and depression. Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in the US are promethazine, metoclopramide, and the newer ondansetron. The word nausea is from Lat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fatigue (medical)
Fatigue describes a state of tiredness that does not resolve with rest or sleep. In general usage, fatigue is synonymous with extreme tiredness or exhaustion that normally follows prolonged physical or mental activity. When it does not resolve after rest or sleep, or occurs independently of physical or mental exertion, it may be a symptom of a medical condition that may become severe or progressive. Fatigue can be a feature of a mental disorder such as depression; may be associated with conditions of chronic pain such as fibromyalgia; it may also feature in conditions of chronic low-level inflammation, and be a disease-related symptom in many other conditions. Fatigue often has no known cause, and is recognised as being very complex in nature. Fatigability describes a susceptibility to fatigue. Physical fatigue results from muscle fatigue brought about by intense physical activity. Mental fatigue results from prolonged periods of cognitive activity which impairs cognitive abil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Daily
''Science Daily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. The site was founded by married couple Dan and Michele Hogan in 1995; Dan Hogan formerly worked in the public affairs department of Jackson Laboratory writing press releases. The site makes money from selling advertisements. As of 2010, the site said that it had grown "from a two-person operation to a full-fledged news business with worldwide contributors". At the time, it was run out of the Hogans' home, had no reporters, and only reprinted press releases. In 2012, Quantcast Quantcast is an American technology company, founded in 2006, that specializes in AI-driven real-time advertising, audience insights and measurement. It has offices in the United States, Canada, Australia, Singapore, United Kingdom, Ireland, Fran ... ranked it at 614 with 2.6 million U.S. vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serological
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including ELISA, agglutinati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
