Ehrlich Pathway
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Ehrlich Pathway
Felix Ehrlich (16 June 1877 in Harriehausen (today incorporated into Bad Gandersheim) – 23 January 1942 in Obernigk near Breslau) was a German chemist and biochemist. Life and work Felix Ehrlich studied in Berlin and Munich. After receiving his doctorate in 1900, he worked at the Institute of Sugar Industry in Berlin. In 1906 he obtained his diploma in chemistry. From 1909 he worked as professor in Breslau, and later as director of the Institute on Biotechnology and Agriculture. Ehrlich discovered the amino acid isoleucine in hemoglobin in 1903, developed a process for resolving racemic amino acids in 1906, described the formation of fusel oils by fermentation, amino acid during alcoholic fermentation in 1905 and worked on the structure of pectins. Ehrlich demonstrated that yeast attacks the natural amino acids essentially by splitting off carbon dioxide and replacing the amino group with hydroxyl. By this reaction, the tryptophan gives rise to tryptophol. Honours 1931 E ...
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Harriehausen
Bad Gandersheim ( Eastphalian: ''Ganderssen'') is a town in southern Lower Saxony, Germany, located in the district of Northeim. , it had a population of 9,492. Bad Gandersheim has many half-timbered houses and is located on the German Timber-Frame Road (german: Deutsche Fachwerkstraße). The town contains an airport as well. Geography The town of Bad Gandersheim lies between the Leine Uplands, Weser Uplands, and Harz Foreland in the valley of the Gande River, into which its tributary, the Eterna, empties within the town's territory. To the north lies the Heber Ridge. The borough is predominantly hilly. The Harz Mountains begin about east of the town, and to the west is the Leine Graben (german: Leinegraben). Borough divisions The borough of Bad Gandersheim consists of the following subdivisions based on the surrounding villages: History The town dates back to 852, when Gandersheim Abbey, a house of secular canonesses, was created in nearby Brunshausen by Liudolf, Du ...
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Hydroxyl
In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom. In organic chemistry, alcohols and carboxylic acids contain one or more hydroxy groups. Both the negatively charged anion , called hydroxide, and the neutral radical , known as the hydroxyl radical, consist of an unbonded hydroxy group. According to IUPAC definitions, the term ''hydroxyl'' refers to the hydroxyl radical () only, while the functional group is called a ''hydroxy group''. Properties Water, alcohols, carboxylic acids, and many other hydroxy-containing compounds can be readily deprotonated due to a large difference between the electronegativity of oxygen (3.5) and that of hydrogen (2.1). Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this f ...
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1942 Deaths
Year 194 ( CXCIV) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Septimius and Septimius (or, less frequently, year 947 ''Ab urbe condita''). The denomination 194 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus and Decimus Clodius Septimius Albinus Caesar become Roman Consuls. * Battle of Issus: Septimius Severus marches with his army (12 legions) to Cilicia, and defeats Pescennius Niger, Roman governor of Syria. Pescennius retreats to Antioch, and is executed by Severus' troops. * Septimius Severus besieges Byzantium (194–196); the city walls suffer extensive damage. Asia * Battle of Yan Province: Warlords Cao Cao and Lü Bu fight for control over Yan Province; the battle lasts for over 100 ...
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1877 Births
Events January–March * January 1 – Queen Victoria is proclaimed ''Empress of India'' by the ''Royal Titles Act 1876'', introduced by Benjamin Disraeli, the Prime Minister of the United Kingdom . * January 8 – Great Sioux War of 1876 – Battle of Wolf Mountain: Crazy Horse and his warriors fight their last battle with the United States Cavalry in Montana. * January 20 – The Conference of Constantinople ends, with Ottoman Turkey rejecting proposals of internal reform and Balkan provisions. * January 29 – The Satsuma Rebellion, a revolt of disaffected samurai in Japan, breaks out against the new imperial government; it lasts until September, when it is crushed by a professionally led army of draftees. * February 17 – Major General Charles George Gordon of the British Army is appointed Governor-General of the Sudan. * March – ''The Nineteenth Century (periodical), The Nineteenth Century'' magazine is founded in London. * Marc ...
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Emil Fischer Medal
Emil or Emile may refer to: Literature *''Emile, or On Education'' (1762), a treatise on education by Jean-Jacques Rousseau * ''Émile'' (novel) (1827), an autobiographical novel based on Émile de Girardin's early life *''Emil and the Detectives'' (1929), a children's novel *"Emil", nickname of the Kurt Maschler Award for integrated text and illustration (1982–1999) *''Emil i Lönneberga'', a series of children's novels by Astrid Lindgren Military *Emil (tank), a Swedish tank developed in the 1950s * Sturer Emil, a German tank destroyer People *Emil (given name), including a list of people with the given name ''Emil'' or ''Emile'' *Aquila Emil (died 2011), Papua New Guinean rugby league footballer Other * ''Emile'' (film), a Canadian film made in 2003 by Carl Bessai *Emil (river), in China and Kazakhstan See also * * *Aemilius (other) *Emilio (other) *Emílio (other) *Emilios (other) Emilios, or Aimilios, (Greek: Αιμίλιος) is a ...
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Tryptophol
Tryptophol is an aromatic alcohol that induces sleep in humans. It is found in wine as a secondary product of ethanol fermentation. It was first described by Felix Ehrlich in 1912. It is also produced by the trypanosomal parasite in sleeping sickness. It forms in the liver as a side-effect of disulfiram treatment. Natural occurrences Tryptophol can be found in ''Pinus sylvestris'' needles or seeds. It is produced by the trypanosomal parasite (''Trypanosoma brucei'') in sleeping sickness (African trypanosomiasis). Tryptophol is found in wine and beer as a secondary product of ethanol fermentation (a product also known as congener) by ''Saccharomyces cerevisiae''. It is also an autoantibiotic produced by the fungus ''Candida albicans. It can also be isolated from the marine sponge ''Ircinia spiculosa''. Metabolism Biosynthesis It was first described by Felix Ehrlich in 1912. Ehrlich demonstrated that yeast attacks the natural amino acids essentially by splitting off carbon dio ...
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Tryptophane
Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an Alpha_and_beta_carbon , α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar Aromatic hydrocarbon, aromatic Alpha and beta carbon, beta carbon substituent. It is Essential amino acid, essential in humans, meaning that the body cannot synthesize it and it must be obtained from the diet. Tryptophan is also a precursor to the neurotransmitter serotonin, the hormone melatonin, and vitamin B3. It is Genetic code, encoded by the codon UGG. Like other amino acids, tryptophan is a zwitterion at physiological pH where the amino group is protonated (–; pKa = 9.39) and the carboxylic acid is deprotonation, deprotonated ( –COO−; pKa = 2.38). Humans and many animals cannot synthesize tryptophan: they need to obtain it through their diet, making it an essential amino acid. Function Amino acids, including ...
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Amino Group
In chemistry, amines (, ) are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines). Important amines include amino acids, biogenic amines, trimethylamine, and aniline; Inorganic derivatives of ammonia are also called amines, such as monochloramine (). The substituent is called an amino group. Compounds with a nitrogen atom attached to a carbonyl group, thus having the structure , are called amides and have different chemical properties from amines. Classification of amines Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic a ...
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Carbon Dioxide
Carbon dioxide (chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas. It is a trace gas in Earth's atmosphere at 421 parts per million (ppm), or about 0.04% by volume (as of May 2022), having risen from pre-industrial levels of 280 ppm. Burning fossil fuels is the primary cause of these increased CO2 concentrations and also the primary cause of climate change.IPCC (2022Summary for policy makersiClimate Change 2022: Mitigation of Climate Change. Contribution of Working Group III to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA Carbon dioxide is soluble in water and is found in groundwater, lakes, ice caps, ...
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Pectin
Pectin ( grc, πηκτικός ': "congealed" and "curdled") is a heteropolysaccharide, a structural acid contained in the primary lamella, in the middle lamella, and in the cell walls of terrestrial plants. The principal, chemical component of pectin is galacturonic acid (a sugar acid derived from galactose) which was isolated and described by Henri Braconnot in 1825. Commercially produced pectin is a white-to-light-brown powder, produced from citrus fruits for use as an edible gelling agent, especially in jams and jellies, dessert fillings, medications, and sweets; and as a chemical stabiliser in fruit juices and milk drinks, and as a source of dietary fiber. Biology Pectin is composed of complex polysaccharides that are present in the primary cell walls of a plant, and are abundant in the green parts of terrestrial plants. Pectin is the principal component of the middle lamella, where it binds cells. Pectin is deposited by exocytosis into the cell wall via vesicles produc ...
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