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Edward Perl
Edward Roy Perl (October 6, 1926 – July 15, 2014) was an American neuroscientist whose research focused on neural mechanisms of and circuitry involved in somatic sensation, principally nociception. Work in his laboratory in the late 1960s established the existence of unique nociceptors. Perl was one of the founding members of the Society for Neuroscience and served as its first president. He was a Sarah Graham Kenan Professor of Cell Biology & Physiology and a member of the UNC Neuroscience Center at the University of North Carolina School of Medicine. Early life and military training Perl was born in Chicago, Illinois to John and Blanche Perl, natives of Hungary and Czechoslovakia, respectively. As a child, Perl was fascinated by electricity, which led to an interest in electronics, radio, and the sciences. In college at the University of Chicago, Perl focused on physics and engineering, but a conversation with his father, who was a physician and surgeon, convinced him to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Lakes Naval Station
Naval Station Great Lakes (NAVSTA Great Lakes) is the home of the United States Navy's only boot camp, located near North Chicago, in Lake County, Illinois. Important tenant commands include the Recruit Training Command, Training Support Center and Navy Recruiting District Chicago. Naval Station Great Lakes is the largest military installation in Illinois and the largest training station in the Navy. The base has 1,153 buildings situated on and has of roadway to provide access to the base's facilities. Within the naval service, it has several different nicknames, including "The Quarterdeck of the Navy", or the more derogatory "Great Mistakes". It is also referred to as "second boot camp" while at Training Support Command. The original 39 buildings built between 1905 and 1911 were designed by Jarvis Hunt. The base functions similarly to a small city, with its own fire department, Naval Security Forces (Police), and public works department. One of the landmarks of the area is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophysiological
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , ''-logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vernon Mountcastle
Vernon Benjamin Mountcastle (July 15, 1918 – January 11, 2015) was an American neurophysiologist and Professor Emeritus of Neuroscience at Johns Hopkins University. He discovered and characterized the columnar organization of the cerebral cortex in the 1950s. This discovery was a turning point in investigations of the cerebral cortex, as nearly all cortical studies of sensory function after Mountcastle's 1957 paper, on the somatosensory cortex, used columnar organization as their basis. Early life and education Vernon Benjamin Mountcastle was born on July 15, 1918, in Shelbyville, Kentucky as the third of five children into a family of "farmers, industrial entrepreneurs, or builders of railroads". In 1921 his family moved to Roanoke, Virginia where he went to elementary and junior high school and was "an enthusiastic Boy Scout". Because his mother, a former teacher, had taught him to read and write when he was 4 years old, he immediately moved ahead two grades when entering t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest Philanthropy, philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as :Presidents of Johns Hopkins University, Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all Higher education in the U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated by electrophysiology—the electrical recording of neural activity ranging from the molar (the electroencephalogram, EEG) to the cellular (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field potentials. However, since the neurone is an electrochemical machine, it is difficult to isolate electrical events from the metabolic and molecular processes that cause them. Thus, neurophysiologists currently utilise tools from chemistry (calcium imaging), physics (functional magnetic resonance imaging, Functional magnetic resonance imaging, fMRI), and molecular biology (site directed mutations) to examine brain activity. The word originates f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derek Denny-Brown
Derek Ernest Denny-Brown OBE (1901 – 20 April 1981) was a New Zealand-born neurologist. Working in Oxford, London and Boston, he made major contributions to the field of neurology, such as the development of electromyography, physiology of micturition and the treatment of Wilson's disease. Biography Born in New Zealand, he studied at the University of Otago at Dunedin, South Island, where he qualified in medicine in 1924. He then took up a fellowship to perform research at the department of Dr Sir Charles Scott Sherrington, where he studied motor neuron physiology. He obtained a DPhil and published sixteen scientific papers on his research. In 1928 he took up a clinical post at the National Hospital for Neurology and Neurosurgery in London, and over the subsequent years underwent neurological specialist training, as well as serving as a lecturer, at the National Hospital and Guy's Hospital. The National Hospital was at the forefront of the developing specialty of neurology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurologist
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurgery. Histor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston City Hospital
The Boston City Hospital (1864–1996), in Boston, Massachusetts, was a public hospital, located in the South End. It was "intended for the use and comfort of poor patients, to whom medical care will be provided at the expense of the city, and ... to provide accommodations and medical treatment to others, who do not wish to be regarded as dependent on public charity."Boston Directory (1864) In 1996, it merged with the Boston University Medical Center Hospital to form the Boston Medical Center. This building is currently under study for Boston Landmark status by the Boston Landmarks Commission. History In the mid-19th century, "the hospital was suggested ... by Elisha Goodnow, who, by his will, dated July 12, 1849, gave property to the city valued at $25,000, for establishment of a free city hospital in Wards Eleven or Twelve." Architect Gridley James Fox Bryant designed the first hospital, built 1861–1864 on Harrison Avenue in the South End. It was renovated in 1875 and aga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Impedance Cardiography
Impedance cardiography (ICG) is a non-invasive technology measuring total electrical conductivity of the thorax and its changes in time to process continuously a number of cardiodynamic parameters, such as stroke volume (SV), heart rate (HR), cardiac output (CO), ventricular ejection time (VET), pre-ejection period and used to detect the impedance changes caused by a high-frequency, low magnitude current flowing through the thorax between additional two pairs of electrodes located outside of the measured segment. The sensing electrodes also detect the ECG signal, which is used as a timing clock of the system. Introduction Impedance cardiography (ICG), also referred to as electrical impedance plethysmography (EIP) or Thoracic Electrical Bioimpedance (TEB) has been researched since the 1940s. NASA helped develop the technology in the 1960s. The use of impedance cardiography in psychophysiological research was pioneered by the publication of an article by Miller and Horvath in 197 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science (journal)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
