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Edward Jenner
Edward Jenner, (17 May 1749 – 26 January 1823) was a British physician and scientist who pioneered the concept of vaccines, and created the smallpox vaccine, the world's first vaccine. The terms ''vaccine'' and ''vaccination'' are derived from ''Variolae vaccinae'' ('pustules of the cow'), the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his ''Inquiry into the Variolae vaccinae known as the Cow Pox'', in which he described the protective effect of cowpox against smallpox. In the West, Jenner is often called "the father of immunology", and his work is said to have saved "more lives than any other man". In Jenner's time, smallpox killed around 10% of global population, with the number as high as 20% in towns and cities where infection spread more easily. In 1821, he was appointed physician to King George IV of the United Kingdom, George IV, and was also made mayor of Berkeley, Gloucestershire, Berkeley and justice of the peace. A member of the Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berkeley, Gloucestershire
Berkeley ( ) is a market town and civil parishes in England, parish in the Stroud (district), Stroud District in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway. The town is noted for Berkeley Castle, where the imprisoned Edward II of England, King Edward II is believed to have been murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish includes the village of Berkeley Heath, which runs along the A38 road, A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Geography Berkeley lies midway between Bristol and Gloucester, on a small hill in the Vale of Berkeley. The town is on the Little Avon River, which flows into the Severn at Pil (placename), Berkeley Pill. The Little Avon was tidal, and so navigable, for some distance inland (as far as Berkeley itself and the Sea Mills at Ham) until a 'tidal reservoir' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Cuckoo
The common cuckoo (''Cuculus canorus'') is a member of the cuckoo order of birds, Cuculiformes, which includes the roadrunners, the anis and the coucals. This species is a widespread summer migrant to Europe and Asia, and winters in Africa. It is a brood parasite, which means it lays eggs in the nests of other bird species, particularly of dunnocks, meadow pipits, and reed warblers. Although its eggs are larger than those of its hosts, the eggs in each type of host nest resemble the host's eggs. The adult too is a mimic, in its case of the sparrowhawk; since that species is a predator, the mimicry gives the female time to lay her eggs without being attacked. Taxonomy The species' binomial name is derived from the Latin ''cuculus'' (the cuckoo) and ''canorus'' (melodious; from ''canere'', meaning to sing). The cuckoo family gets its common name and genus name by onomatopoeia for the call of the male common cuckoo. The English word "cuckoo" comes from the Old French ''cucu'', ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chipping Sodbury
Chipping Sodbury is a market town and former civil parish, now in the parish of Sodbury, in the unitary authority area of South Gloucestershire, in the ceremonial county of Gloucestershire, England. It was founded in the 12th century by William le Gros. It is the principal settlement in the civil parish of Sodbury, which also includes the village of Old Sodbury. Little Sodbury is a nearby but separate civil parish. Sodbury parish council has elected to be known as Sodbury Town Council. At the 2011 census the population of Chipping Sodbury was 5,045, but in the last decade the town has become part of a much larger built-up area due to the rapid expansion of nearby Yate, with which it is contiguous to the west. At the census the combined population of Yate and Chipping Sodbury was 26,834. Governance An electoral ward in the same name (not Sodbury) exists. This ward starts in the north at Chipping Sodbury Golf Course and stretches south to Dodington. The total population of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as physicians before specializing in surgery. There are also surgeons in podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Ira D. Papel, John Frodel, ''Facial Plastic and Reconstructive Surgery'' His magnum opus ''Suśruta-saṃhitā'' is one of the most important surviving ancient treatises on medicine and is considered a foundational text of both Ayurveda and surgery. The treatise addresses all aspects of general medicine, but the translator G. D. Si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Variolation
Variolation was the method of inoculation first used to immunize individuals against smallpox (''Variola'') with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Variolation is no longer used today. It was replaced by the smallpox vaccine, a safer alternative. This in turn led to the development of the many vaccines now available against other diseases. The procedure was most commonly carried out by inserting/rubbing powdered smallpox scabs or fluid from pustules into superficial scratches made in the skin. The virus was normally spread through the air, infecting first the mouth, nose, or respiratory tract, before spreading throughout the body via the lymphatic system. In contrast, infection of the skin usually led to a milder, localized infection, but, crucially, still induced immunity to the virus. The patient would develop pustules like those caused by naturally acquired smallpox. Eventually, after ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inoculation
Inoculation is the act of implanting a pathogen or other microorganism. It may refer to methods of artificially inducing immunity against various infectious diseases, or it may be used to describe the spreading of disease, as in "self-inoculation," the spreading of disease from one part of the body to another, or even to the spreading of bacteria in a Petri dish for culturing purposes. The terms "inoculation", "vaccination", and "immunization" are often used synonymously, but there are some important differences among them. Inoculation is the act of implanting a disease inside a person or animal, vaccination is the act of implanting or giving someone a vaccine specifically, and immunization is what happens to the immune system as a result. Terminology Until the early 1800s inoculation referred only to variolation (from the Latin word ''variola'' = smallpox), the predecessor to the smallpox vaccine. The smallpox vaccine, introduced by Edward Jenner in 1796, was called cowpox inoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cirencester
Cirencester (, ; see below for more variations) is a market town in Gloucestershire, England, west of London. Cirencester lies on the River Churn, a tributary of the River Thames, and is the largest town in the Cotswolds. It is the home of the Royal Agricultural University, the oldest agricultural college in the English-speaking world, founded in 1840. The town had a population of 20,229 in 2021. The Roman name for the town was Corinium, which is thought to have been associated with the ancient British tribe of the ''Dobunni'', having the same root word as the River Churn. The earliest known reference to the town was by Ptolemy in AD 150. The town's Corinium Museum has an extensive Roman collection. Cirencester is twinned with the town of Itzehoe, in the Steinburg region of Germany. Local geography Cirencester lies on the lower dip slopes of the Cotswold Hills, an outcrop of oolitic limestone. Natural drainage is into the River Churn, which flows roughly north to south ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wotton-under-Edge
Wotton-under-Edge is a market town within the Stroud district of Gloucestershire, England. Located near the southern fringe of the Cotswolds, the Cotswold Way long-distance footpath passes through the town. Standing on the B4058, Wotton is about from the M5 motorway. The nearest railway station is Cam and Dursley, away by road, on the Bristol to Birmingham line. History The first record of the town is in an Anglo-Saxon Royal Charter of King Edmund I, who in AD 940 leased four hides of land in ''Wudetun'' to Eadric. The name ''Wudetun'' means the enclosure, homestead or village (''tun'') in or near the wood (''wude''). The "Edge" refers to the limestone escarpment of the Cotswold Edge which includes the hills of Wotton Hill and Tor Hill that flank the town. In the 1086 Domesday Book listing, Wotton was in the hundred of Dudstone. Kingswood Abbey was founded in 1139, but all that remains is a 16th-century Cistercian gatehouse. Nearby historical buildings include the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vicar
A vicar (; Latin: ''vicarius'') is a representative, deputy or substitute; anyone acting "in the person of" or agent for a superior (compare "vicarious" in the sense of "at second hand"). Linguistically, ''vicar'' is cognate with the English prefix "vice", similarly meaning "deputy". The title appears in a number of Christian ecclesiastical contexts, but also as an administrative title, or title modifier, in the Roman Empire. In addition, in the Holy Roman Empire a local representative of the emperor, perhaps an archduke, might be styled "vicar". Roman Catholic Church The Pope uses the title ''Vicarius Christi'', meaning the ''vicar of Christ''. In Catholic canon law, ''a vicar is the representative of any ecclesiastic'' entity. The Romans had used the term to describe officials subordinate to the praetorian prefects. In the early Christian churches, bishops likewise had their vicars, such as the archdeacons and archpriests, and also the rural priest, the curate who had the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Reverend
The Reverend is an style (manner of address), honorific style most often placed before the names of Christian clergy and Minister of religion, ministers. There are sometimes differences in the way the style is used in different countries and church traditions. ''The Reverend'' is correctly called a ''style'' but is often and in some dictionaries called a title, form of address, or title of respect. The style is also sometimes used by leaders in other religions such as Judaism and Buddhism. The term is an anglicisation of the Latin ''reverendus'', the style originally used in Latin documents in medieval Europe. It is the gerundive or future passive participle of the verb ''revereri'' ("to respect; to revere"), meaning "[one who is] to be revered/must be respected". ''The Reverend'' is therefore equivalent to ''The Honourable'' or ''The Venerable''. It is paired with a modifier or noun for some offices in some religious traditions: Lutheran archbishops, Anglican archbishops, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Jenner Manuscript
Edward is an English given name. It is derived from the Anglo-Saxon name ''Ēadweard'', composed of the elements '' ēad'' "wealth, fortune; prosperous" and '' weard'' "guardian, protector”. History The name Edward was very popular in Anglo-Saxon England, but the rule of the Norman and Plantagenet dynasties had effectively ended its use amongst the upper classes. The popularity of the name was revived when Henry III named his firstborn son, the future Edward I, as part of his efforts to promote a cult around Edward the Confessor, for whom Henry had a deep admiration. Variant forms The name has been adopted in the Iberian peninsula since the 15th century, due to Edward, King of Portugal, whose mother was English. The Spanish/Portuguese forms of the name are Eduardo and Duarte. Other variant forms include French Édouard, Italian Edoardo and Odoardo, German, Dutch, Czech and Romanian Eduard and Scandinavian Edvard. Short forms include Ed, Eddy, Eddie, Ted, Teddy and Ned. Peop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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