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East Cambridge, Cambridge, Massachusetts
East Cambridge is a neighborhood of Cambridge, Massachusetts. Referred to in modern times as Area 1, East Cambridge is bounded by the Charles River and the Charlestown neighborhood of Boston on the east, the Somerville border on the north, Broadway and Main Street on the south, and the railroad tracks on the west. Most of the streets form a grid aligned with Cambridge Street, which was laid out to directly connect what is now the Charles River Dam Bridge with what in 1809 was the heart of Cambridge, Harvard Square. The northern part of the grid is a roughly six by eight block residential area. Cambridge Street itself is retail commercial, along with Monsignor O'Brien Highway, the Twin Cities Plaza strip mall, and the enclosed Cambridgeside Galleria. Lechmere Square is the transportation hub for the northern side. The southern half of the grid is largely office and laboratory space for hundreds of dot-com companies, research labs and startups associated with MIT, biotechno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1854 EastCambridgeMA Map ByWalling BPL 12775
Events January–March * January 4 – The McDonald Islands are discovered by Captain William McDonald aboard the ''Samarang''. * January 6 – The fictional detective Sherlock Holmes is perhaps born. * January 9 – The Teutonia Männerchor in Pittsburgh, U.S.A. is founded to promote German culture. * January 20 – The North Carolina General Assembly in the United States charters the Atlantic and North Carolina Railroad, to run from Goldsboro through New Bern, to the newly created seaport of Morehead City, near Beaufort. * January 21 – The iron clipper runs aground off the east coast of Ireland, on her maiden voyage out of Liverpool, bound for Australia, with the loss of at least 300 out of 650 on board. * February 11 – Major streets are lit by coal gas for the first time by the San Francisco Gas Company; 86 such lamps are turned on this evening in San Francisco, California. * February 13 – Mexican troops force William Wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moderna
Moderna, Inc. ( ) is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The company's only commercial product is the Moderna COVID-19 vaccine, marketed as Spikevax. As of 2022, the company has 44 treatment and vaccine candidates, of which 21 have entered clinical trials. Targets for vaccine candidates include influenza, HIV, respiratory syncytial virus, Epstein–Barr virus, the Nipah virus, chikungunya, a combined single-shot COVID-19 booster and influenza vaccine, a cytomegalovirus vaccine, and two cancer vaccines. The company's pipeline also includes candidates for cancer immunotherapy using OX40 ligand, interleukin 23, IL36G, and interleukin 12 as well as, in partnership with AstraZeneca, a regenerative medicine treatment that encodes vascular endothelial growth factor A to stimul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grand Junction Railroad
Grand may refer to: People with the name * Grand (surname) * Grand L. Bush (born 1955), American actor * Grand Mixer DXT, American turntablist * Grand Puba (born 1966), American rapper Places * Grand, Oklahoma * Grand, Vosges, village and commune in France with Gallo-Roman amphitheatre * Grand Concourse (other), several places * Grand County (other), several places * Grand Geyser, Upper Geyser Basin of Yellowstone * Grand Rounds National Scenic Byway, a parkway system in Minneapolis, Minnesota, United States * Le Grand, California, census-designated place * Grand Staircase, a place in the US. Arts, entertainment, and media * ''Grand'' (Erin McKeown album), 2003 * ''Grand'' (Matt and Kim album), 2009 * ''Grand'' (magazine), a lifestyle magazine related to related to grandparents * ''Grand'' (TV series), American sitcom, 1990 * Grand piano, musical instrument * Grand Production, Serbian record label company * The Grand Tour, a new British automobile show Oth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fitchburg Railroad
The Fitchburg Railroad is a former railroad company, which built a railroad line across northern Massachusetts, United States, leading to and through the Hoosac Tunnel. The Fitchburg was leased to the Boston and Maine Railroad in 1900. The main line from Boston to Fitchburg is now operated as the MBTA Fitchburg Line; Pan Am Railways runs freight service on some other portions. History Early history A horse-drawn railroad from Boston to Brattleboro, Vermont, via Fitchburg was proposed in 1828. The Charlestown Branch Railroad was incorporated April 4, 1835, as a short branch from the Boston and Lowell Railroad near Lechemere Point in Cambridge, across the Miller's River to the Charlestown waterfront, ending at Swett's Wharf (Sweet's Wharf in some sources) right before the Charlestown Navy Yard. It opened in January 1840 with horse-drawn trains. The Fitchburg Railroad was incorporated March 3, 1842, to run from Boston to Fitchburg, and bought land next to the Charlestown Bran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston And Lowell Railroad
The Boston and Lowell Railroad was a railroad that operated in Massachusetts in the United States. It was one of the first railroads in North America and the first major one in the state. The line later operated as part of the Boston and Maine Railroad's Southern Division. Formation The Boston and Lowell Railroad was preceded by the Middlesex Canal. Converting the canal to a railroad would eliminate the issue of transportation being unavailable during the winter, when the canal froze. Patrick Tracy Jackson led the task of convincing the state legislature to fund the project. This proved difficult, as the investors of the Middlesex Canal were against building a new form of transportation designed to replace their canal. Because, prior to 1872, there was no provision in Massachusetts state law for chartering railroads, all had to be chartered by special acts of legislature. This made it slow and inefficient to charter a railroad because the politicians had to agree; the issue w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middlesex Turnpike (Massachusetts)
The Middlesex Turnpike was an early turnpike between Cambridge and Tyngsborough, Massachusetts and the New Hampshire border, where it connected with the Amherst Turnpike and thence Nashua and Claremont, New Hampshire. The turnpike was chartered on June 15, 1805, by the Massachusetts legislature. After an extremely contentious argument about its route, it opened about five years later. The road started near present-day Technology Square in East Cambridge, where it intersected with the Cambridge and Concord Turnpike (now Broadway), headed roughly northwest along what are now Hampshire and Beacon Streets, passed by the 'Foot of the Rocks' in West Cambridge (now along Massachusetts Avenue in Arlington), and onwards to Lexington by today's Westminster and Lowell Streets. From there, it continued through Burlington, Bedford, and Billerica, the section of which is still called the Middlesex Turnpike as far as Concord Road in Billerica (though between 2010 and 2016 the roadway official ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middlesex Canal
The Middlesex Canal was a 27-mile (44-kilometer) barge canal connecting the Merrimack River with the port of Boston. When operational it was 30 feet (9.1 m) wide, and 3 feet (0.9 m) deep, with 20 locks, each 80 feet (24 m) long and between 10 and 11 feet (3.0 and 3.4 m) wide. It also had eight aqueducts. Built from 1793 to 1803, the canal was one of the first civil engineering projects of its type in the United States, and was studied by engineers working on other major canal projects such as the Erie Canal. A number of innovations made the canal possible, including hydraulic cement, which was used to mortar its locks, and an ingenious floating towpath to span the Concord River. The canal operated until 1851, when more efficient means of transportation of bulk goods, largely railroads, meant it was no longer competitive. In 1967, the canal was designated a National Historic Civil Engineering Landmark by the American Society of Civil Engineers. Remnants of the canal still surviv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Bulfinch
Charles Bulfinch (August 8, 1763 – April 15, 1844) was an early American architect, and has been regarded by many as the first American-born professional architect to practice.Baltzell, Edward Digby. ''Puritan Boston & Quaker Philadelphia''. Transaction Publishers (1996), p. 322-24. . Life Bulfinch split his career between his native Boston, Massachusetts, and Washington, D.C., where he served as Commissioner of Public Building and built the intermediate United States Capitol rotunda and dome. His works are notable for their simplicity, balance, and good taste, and as the origin of a distinctive Federal style of classical domes, columns, and ornament that dominated early 19th-century American architecture. Early life Bulfinch was born in Boston to Thomas Bulfinch, a prominent physician, and his wife, Susan Apthorp, daughter of Charles Apthorp. At the age of 12, he watched the Battle of Bunker Hill from this home on the Boston side of the Charles River. He was educated at Bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middlesex County, Massachusetts
Middlesex County is located in the Commonwealth (U.S. state), Commonwealth of Massachusetts, in the United States. As of the 2020 census, the population was 1,632,002, making it the most populous county in both Massachusetts and New England and the List of the most populous counties in the United States, 22nd most populous county in the United States. Middlesex County is one of two U.S. counties (along with Santa Clara County, California) to be amongst the top 25 counties with the highest household income and the 25 most populated counties. It is included in the Census Bureau's Boston–Cambridge, Massachusetts, Cambridge–Newton, Massachusetts, Newton, MA–New Hampshire, NH Greater Boston, Metropolitan Statistical Area. As part of the 2020 United States census, the Commonwealth's mean center of population for that year was Geographic coordinate system, geo-centered in Middlesex County, in the town of Natick, Massachusetts, Natick (this is not to be confused with the geographic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Craigie's Bridge
The Charles River Dam Bridge, officially the Craigie Bridge, also called Craigie's Bridge or the Canal Bridge, is a six-lane bascule bridge across the Charles River in the West End neighborhood of Boston. The bridge, maintained by the Massachusetts Department of Conservation and Recreation (DCR, formerly the MDC), carries Massachusetts Route 28 (Charles River Dam Road at this location) next to the Green Line's Lechmere Viaduct. The Museum of Science is located on the dam and nearby piers. Charles River Dam Road connects Leverett Circle in the West End to East Cambridge, but most of the road is fixed, and the asymmetrically sited drawbridge is a short span entirely on the Boston side of the river. The original lock for the Charles River was incorporated into the dam, just west of the Charles River Dam Bridge, but it was replaced by three parallel locks in the new Charles River Dam, located further east, at the site of the old Warren Bridge. The former lock at the Charles Rive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Battles Of Lexington And Concord
The Battles of Lexington and Concord were the first military engagements of the American Revolutionary War. The battles were fought on April 19, 1775, in Middlesex County, Province of Massachusetts Bay, within the towns of Lexington, Concord, Lincoln, Menotomy (present-day Arlington), and Cambridge. They marked the outbreak of armed conflict between the Kingdom of Great Britain and its thirteen colonies in America. In late 1774, Colonial leaders adopted the Suffolk Resolves in resistance to the alterations made to the Massachusetts colonial government by the British parliament following the Boston Tea Party. The colonial assembly responded by forming a Patriot provisional government known as the Massachusetts Provincial Congress and calling for local militias to train for possible hostilities. The Colonial government effectively controlled the colony outside of British-controlled Boston. In response, the British government in February 1775 declared Massachusetts to be in a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millers River (Middlesex)
Millers River (frequently written as Miller's River) was a river in Middlesex County, Massachusetts. It has since mostly been obscured by landfill and "made land" (land created by filling of waterways). The small remaining estuary is a remnant of wetlands and open water that once divided Cambridge from Charlestown, Massachusetts. The exact historical course of parts the river is somewhat uncertain, and thus parts of the Charlestown-Cambridge and Somerville-Cambridge borders may have changed due to incorrect historical reconstruction. History Millers River flowed into the Charles River, providing water transport to commercial and industrial sites along its shores beginning in the early colonial period. It was previously called Willis Creek and is labeled as such on the 1777 Pelham Map, among others. In the late 19th century, Millers River was used as a dumping place for wastes from abattoirs and slaughterhouses. The stench and health problems related to this use resulted in some ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
