EGOT (other)
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EGOT (other)
EGOT is an acronym for "Emmy, Grammy, Oscar, Tony" in reference to persons who have won all four awards. EGOT may also refer to: * EGOT (gene), the Eosinophil Granule Ontogeny Transcript non-protein coding gene which encodes a long noncoding RNA molecule * EGOT, the enzyme Erythrocyte Glutamic Oxaloacetic Transferase * EGOT, the enzyme Erythrocyte Glutamate Oxaloacetate Transaminase {{disambig ...
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EGOT (gene)
EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript ( non-protein coding), is a human gene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 (ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ''ITPR1'' gene. Interactions ITPR1 has been shown to interact with: * AHCYL1, * CA8, * EPB41L1 * FKBP1A, * MRVI1, * PRKG1, * RHOA Transform ...) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression. Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals. †Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature. References {{Reflist Genes on human chromosome 3 Non-coding RNA ...
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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