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EC 2.4
This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald. EC 2.1: Transferring One-Carbon Groups EC 2.1.1: Methyltransferases * : nicotinamide ''N''-methyltransferase * : guanidinoacetate ''N''-methyltransferase * : thetin—homocysteine ''S''-methyltransferase * : acetylserotonin ''O''-methyltransferase * : betaine—homocysteine ''S''-methyltransferase * : catechol ''O''-methyltransferase * : nicotinate ''N''-methyltransferase * : histamine ''N''-methyltransferase * : thiol ''S''-methyltransferase * : homocysteine ''S''-methyltransferase * : magnesium protoporphyrin IX methyltransferase * : methionine ''S''-methyltransferase * : methionine synthase * : 5-methyltetrahydropteroyltr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Commission Number
The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the corresponding enzyme-catalyzed reaction. EC numbers do not specify enzymes but enzyme-catalyzed reactions. If different enzymes (for instance from different organisms) catalyze the same reaction, then they receive the same EC number. Furthermore, through convergent evolution, completely different protein folds can catalyze an identical reaction (these are sometimes called non-homologous isofunctional enzymes) and therefore would be assigned the same EC number. By contrast, UniProt identifiers uniquely specify a protein by its amino acid sequence. Format of number Every enzyme code consists of the letters "EC" followed by four numbers separated by periods. Those numbers represent a progressively finer classification of the enzyme. Preliminary EC ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fatty-acid O-methyltransferase
In enzymology, a fatty-acid O-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + a fatty acid \rightleftharpoons S-adenosyl-L-homocysteine + a fatty acid methyl ester Thus, the two substrates of this enzyme are S-adenosyl methionine and fatty acid, whereas its two products are S-adenosylhomocysteine and fatty acid methyl ester. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:fatty-acid O-methyltransferase. Other names in common use include fatty acid methyltransferase, and fatty acid O-methyltransferase. References * EC 2.1.1 Enzymes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TRNA (guanine-N7-)-methyltransferase
In enzymology, a tRNA (guanine-N7-)-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + tRNA \rightleftharpoons S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA, whereas its two products are S-adenosylhomocysteine and tRNA containing N7-methylguanine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase. Other names in common use include transfer ribonucleate guanine 7-methyltransferase, 7-methylguanine transfer ribonucleate methylase, tRNA guanine 7-methyltransferase, N7-methylguanine methylase, and S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase. Structural studies As of late 2007, two structures A structure is an arrangement and organization of interrel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylethanolamine N-methyltransferase
Phenylethanolamine ''N''-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline). It is also expressed in small groups of neurons in the human brain and in selected populations of cardiomyocytes. Structure PNMT is a protein whose encoding gene is found on chromosome 17 in humans. It consists of 4 exons and is a 30 kDa protein. It shares many properties found among the other methyltransferases. It is closest in sequence to glycine-''N''-methyl transferase ( GNMT). It also shares many structural properties like the shape of the folding lip with catechol-O-methyl transferase (COMT), though it shares less sequence identity. Several features of the structure like this folding lip suggest that PNMT is a recent adaptation to the catecholamine synthesizing enzyme family, evolving later than COMT, but before other methyltransferases like GNMT. ''S''-adenosyl-L-methionine (SAM) is a requir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyramine N-methyltransferase
In enzymology, a tyramine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + tyramine \rightleftharpoons S-adenosyl-L-homocysteine + N-methyltyramine Thus, the two substrates of this enzyme are S-adenosyl methionine and tyramine, whereas its two products are S-adenosylhomocysteine and N-methyltyramine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:tyramine N-methyltransferase. Other names in common use include DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid), S-adenosyl-methionine:tyramine N-methyltransferase, and tyramine methylpherase. This enzyme participates in tyrosine metabolism -Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a non-essential amino acid with a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iodophenol O-methyltransferase
In enzymology, an iodophenol ''O''-methyltransferase () is an enzyme that catalyzes the chemical reaction :''S''-adenosyl-L-methionine + 2-iodophenol \rightleftharpoons ''S''-adenosyl-L-homocysteine + 2-iodophenol methyl ether Thus, the two substrates of this enzyme are ''S''-adenosyl methionine and 2-iodophenol, whereas its two products are ''S''-adenosylhomocysteine and 2-iodophenol methyl ether. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is ''S''-adenosyl-L-methionine:2-iodophenol ''O''-methyltransferase. References * EC 2.1.1 Enzymes of unknown structure {{2.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenol O-methyltransferase
In enzymology, a phenol O-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + phenol \rightleftharpoons S-adenosyl-L-homocysteine + anisole Thus, the two substrates of this enzyme are S-adenosyl methionine and phenol, whereas its two products are S-adenosylhomocysteine and anisole. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:phenol O-methyltransferase. This enzyme is also called PMT. This enzyme participates in tyrosine metabolism -Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a non-essential amino acid with a polar side group. The word "tyrosine" is from the Gr .... References * EC 2.1.1 Enzymes of unknown structure O-methylated natural phenols metabolism ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carnosine N-methyltransferase
In enzymology, a carnosine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + carnosine \rightleftharpoons S-adenosyl-L-homocysteine + anserine Thus, the two substrates of this enzyme are S-adenosyl methionine and carnosine, whereas its two products are S-adenosylhomocysteine and anserine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:carnosine N-methyltransferase. This enzyme participates in histidine metabolism. Gene The genes encoding carnosine ''N''-methyltransferase activity have been identified by Jakub Drozak and coworkers in 201 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylamine—glutamate N-methyltransferase
In enzymology, a methylamine-glutamate ''N''-methyltransferase () is an enzyme that catalyzes the chemical reaction :methylamine + -glutamate \rightleftharpoons NH3 + ''N''-methyl--glutamate Thus, the two substrates of this enzyme are methylamine and -glutamate, whereas its two products are NH3 and ''N''-methyl--glutamate. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is methylamine:-glutamate ''N''-methyltransferase. Other names in common use include ''N''-methylglutamate synthase, and methylamine-glutamate methyltransferase. This enzyme participates in methane metabolism. References * EC 2.1.1 Enzy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycine N-methyltransferase
In enzymology, a glycine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + glycine \rightleftharpoons S-adenosyl-L-homocysteine + sarcosine Thus, the substrates of this enzyme are S-adenosyl methionine and glycine, whereas its two products are S-adenosylhomocysteine and sarcosine. Glycine N-methyltransferase belongs to the family of methyltransferase enzymes. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:glycine N-methyltransferase. Other names in common use include glycine methyltransferase, S-adenosyl-L-methionine:glycine methyltransferase, and GNMT. This family of enzymes participates in the metabolism of multiple amino acids. References * * * * * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trimethylsulfonium—tetrahydrofolate N-methyltransferase
In enzymology, a trimethylsulfonium-tetrahydrofolate N-methyltransferase () is an enzyme that catalyzes the chemical reaction :trimethylsulfonium + tetrahydrofolate \rightleftharpoons dimethylsulfide + 5-methyltetrahydrofolate Thus, the two substrates of this enzyme are trimethylsulfonium and tetrahydrofolate, whereas its two products are dimethyl sulfide and 5-methyltetrahydrofolate Levomefolic acid (INN, also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6''S'')-5-methyltetrahydrofolate, and (6''S'')-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reprodu .... This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is trimethylsulfonium:tetrahydrofolate N-methyltransferase. This enzyme is also called trimethylsulfonium-tetrahydrofolate methyltransferase. This enzyme participates in one carbon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |