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Exserohilum Rostratum
''Setosphaeria rostrata'' is a heat tolerant fungus with an asexual reproductive form (anamorph) known as '' Exserohilum rostratum''. This fungus is a common plant pathogen, causing leaf spots as well as crown rot and root rot in grasses. It is also found in soils and on textiles in subtropical and tropical regions. ''Exserohilum rostratum'' is one of the 35 ''Exserohilum'' species implicated uncommonly as opportunistic pathogens of humans where it is an etiologic agent of sinusitis, keratitis, skin lesions and an often fatal meningoencephalitis. Infections caused by this species are most often seen in regions with hot climates like Israel, India and the southern USA. Growth ''Setosphaeria rostrata'' produce mature conidia with a distinct protruding hilum. The conidia are either straight, curved or bent and the septum above the hilum is thickened and dark. The walls are typically roughened and brown to olive in colour and there are typically 7–9 septa, however, some have 4–1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keratitis
Keratitis is a condition in which the eye's cornea, the clear dome on the front surface of the eye, becomes inflamed. The condition is often marked by moderate to intense pain and usually involves any of the following symptoms: pain, impaired eyesight, photophobia (light sensitivity), red eye and a 'gritty' sensation. Classification (by chronicity) Acute * Acute epithelial keratitis * Nummular keratitis * Interstitial keratitis * Disciform keratitis Chronic * Neurotrophic keratitis * Mucous plaque keratitis Classification (infective) Viral * Herpes simplex keratitis (dendritic keratitis). Viral infection of the cornea is often caused by the herpes simplex virus (HSV) which frequently leaves what is called a 'dendritic ulcer'. * Herpes zoster keratitis, associated with herpes zoster ophthalmicus, which is a form of shingles. Bacterial * Bacterial keratitis. Bacterial infection of the cornea can follow from an injury or from wearing contact lenses. The bacteria involved ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bentazone
Bentazon (Bentazone, Basagran, Herbatox, Leader, Laddock) is a chemical manufactured by BASF Chemicals for use in herbicides. It is categorized under the thiadiazine group of chemicals. Sodium bentazon is available commercially and appears slightly brown in colour. Usage Bentazon is a selective herbicide as it only damages plants unable to metabolize the chemical. It is considered safe for use on alfalfa, beans (with the exception of garbanzo beans ), maize, peanuts, peas (with the exception of blackeyed peas ), pepper, peppermint, rice, sorghum, soybeans and spearmint; as well as lawns and turf. Bentazon is usually applied aerially or through contact spraying on food crops to control the spread of weeds occurring amongst food crops. Herbicides containing bentazon should be kept away from high heat as it will release toxic sulfur and nitrogen fumes. Bentazon is currently registered for use in the United States in accordance with requirements set forth by the United States Envi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylprednisolone
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. Methylprednisolone and its derivatives can be administered orally or parenterally. Regardless of route of administration, methylprednisolone integrates systemically as exhibited by its effectiveness to quickly reduce inflammation during acute flares. It is associated with many adverse reactions that require tapering off the drug as soon as the disease is under control. Serious side effects include iatrogenic Cushing's Syndrome, hypertension, osteoporosis, diabetes, infection, and skin atrophy. Chemically, methylprednisolone is a synthetic pregnane steroid hormone derived from hydrocortisone and prednisolone. It belongs to a class of synthetic glucocorticoids and more generally, corticosteroids. It acts as a min ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New England Compounding Center
New England Compounding Center (NECC) was a compounding pharmacy founded in 1998. Based in Framingham, Massachusetts, NECC was a family-run business owned by Barry J. Cadden, his wife, Lisa Cadden (née Conigliaro) and her brother Gregory Conigliaro. 2012 fungal infection scandal The company became the center of a scandal resulting from a meningitis outbreak that started on May 21, 2012 and is linked to 76 deaths. NECC recalled more than 2,000 products after distributing 17,000 vials of methylprednisolone for injection contaminated with fungi to 23 states. Food and Drug Administration (FDA) regulations dictate that compounding pharmacies like NECC combine, mix, or alter ingredients only to create specific drugs for individual patients. Massachusetts state regulators reported NECC was licensed only to prepare individual patient prescriptions. The company, however, shipped drugs to multiple states, and may have been operating outside of their legal boundaries, authorities said. D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keratomycosis
Fungal keratitis is a fungal infection of the cornea, which can lead to blindness. It generally presents with a red, painful eye and blurred vision. There is also increased sensitivity to light, and excessive tears or discharge. It is caused by fungal organisms such as ''Fusarium'', ''Aspergillus'' or '' Candida''. Fungal keratitis has a worldwide distribution, but is more common in the tropics. Around 1 million people become blind every year due to fungal keratitis. Theodor Leber first described a case of fungal keratitis caused by ''Aspergillus'' in 1879. Signs and symptoms The symptoms of fungal keratitis typically emerge over 5-10 days and present with a painful eye, blurred vision, and redness of eye. There is increased sensitivity to light, and excessive tears or discharge. The symptoms are markedly less as compared to a similar bacterial ulcer. Symptoms may be noted to persist after contact lenses are removed, or following antibiotic treatment. Signs: The eyelids a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poaceae
Poaceae () or Gramineae () is a large and nearly ubiquitous family of monocotyledonous flowering plants commonly known as grasses. It includes the cereal grasses, bamboos and the grasses of natural grassland and species cultivated in lawns and pasture. The latter are commonly referred to collectively as grass. With around 780 genera and around 12,000 species, the Poaceae is the fifth-largest plant family, following the Asteraceae, Orchidaceae, Fabaceae and Rubiaceae. The Poaceae are the most economically important plant family, providing staple foods from domesticated cereal crops such as maize, wheat, rice, barley, and millet as well as feed for meat-producing animals. They provide, through direct human consumption, just over one-half (51%) of all dietary energy; rice provides 20%, wheat supplies 20%, maize (corn) 5.5%, and other grains 6%. Some members of the Poaceae are used as building materials (bamboo, thatch, and straw); others can provide a source of biofuel, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanin
Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. The melanin pigments are produced in a specialized group of cells known as melanocytes. Functionally, eumelanin serves as protection against Ultraviolet, UV radiation. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin, allomelanin and pyomelanin. The most common type is eumelanin, of which there are two types— brown eumelanin and black eumelanin. Pheomelanin, which is produced when melanocytes are malfunctioning due to derivation of the gene to its recessive format is a cysteine-derivative that contains polybenzothiazine portions that are largely responsible for the of red yellow tint given to some skin or hair colors. Neuromelanin is found in the brain. Research ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phaeohyphomycosis
Phaeohyphomycosis is a diverse group of fungal infections, caused by dematiaceous fungi whose morphologic characteristics in tissue include hyphae, yeast-like cells, or a combination of these. It can be associated an array of melanistic filamentous fungi including ''Alternaria'' species'','' ''Exophiala jeanselmei,'' and ''Rhinocladiella mackenziei''. The term "phaeohyphomycosis" was introduced to determine infections caused by dematiaceous (pigmented) filamentous fungi which contain melanin in their cell walls. Phaeohyphomycosis is an uncommon infection, but the number of cases reported has been increasing in recent years. Fungal melanin is thought to be a virulence factor. The outcome of antifungal treatment is poor, and mortality is almost 80%.Sanjay G.R., J.E. Patterson, D.DA. Sutton, R.Pullen, and M.G. Rinaldi. 2002. Disseminated phaeohyphomycosis:review of an emerging Mycosis. Clinical Infectious Disease 34:467-476. Phaeohyphomycosis has been attributed to more than 100 s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dematiaceous
“Black yeasts”, sometimes also black fungi, dematiaceous fungi, microcolonial fungi or meristematic fungi is a diverse group of slow-growing microfungi which reproduce mostly asexually (fungi imperfecti). Only few genera reproduce by budding cells, while in others hyphal or meristematic (isodiametric) reproduction is preponderant. Black yeasts share some distinctive characteristics, in particular a dark colouration ( melanisation) of their cell wall. Morphological plasticity, incrustation of the cell wall with melanins and presence of other protective substances like carotenoids and mycosporines represent passive physiological adaptations which enable black fungi to be highly resistant against environmental stresses. The term " polyextremotolerance" has been introduced to describe this phenotype, a good example of which is the species ''Aureobasidium pullulans''. Presence of 1,8-dihydroxynaphthalene melanin in the cell wall confers to the microfungi their characteristic oliva ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sinusitis
Sinusitis, also known as rhinosinusitis, is inflammation of the nasal mucosa, mucous membranes that line the paranasal sinuses, sinuses resulting in symptoms that may include thick Mucus#Respiratory system, nasal mucus, a nasal congestion, plugged nose, and Orofacial pain, facial pain. Other signs and symptoms may include fever, headaches, a hyposmia, poor sense of smell, sore throat, a feeling that phlegm is oozing out from the back of the nose to the throat along with a necessity to clear the throat frequently and frequent attacks of cough. Generally sinusitis starts off as a common viral infection like common cold. This infection generally subsides within 5 to 7 days. During this time the nasal structures can swell and facilitate the stagnation of fluids in sinuses that leads to acute (medicine), acute sinusitis which lasts from 6th day of the infection to 15th day. From the 15th day to 45th day of the infection comes the subacute stage followed by chronic (medicine), chronic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ascomycota
Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the " ascus" (), a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewers' and bakers' yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens (loosely termed "ascolichens") such as ''Cladonia'' belong to the Ascomycota. Ascomycota is a monophyletic group (it contains all descendants of one common ancestor). Previously placed in the Deuteromycota along with asexual species from other fungal taxa, asexual (or anamorphic) ascomyce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
