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Euphorbia Poissonii
''Euphorbia poissonii'', also known as ''Euphorbia poissoni'' and, incorrectly, as ''Euphorbia poisoni'', is a highly irritant and toxic succulent member of the large and varied spurge family of plants.''Euphorbia poissonii''
in BoDD – Botanical Dermatology Database
It is native to northern , where local farmers extract its for use as a pesticide. Its powerfully irritant and pain-producing nature mandates use as a fencing plant. It is known to the

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Ferdinand Albin Pax
Ferdinand Albin Pax (26 July 1858 – 1 March 1942) was a German botanist specializing in spermatophytes. A collaborator of Adolf Engler, he wrote several monographs and described several species of plants and animals from Silesia and the Carpathians. He was a professor at Wrocław University from 1893. His son Ferdinand Albert Pax (1885–1964) was a noted zoologist. Life and work Pax was born on 26 July 1858 in Dvůr Králové nad Labem, in what was then known as Bohemia, to Carl Ferdinand, a mine superintendent in Schatzlar, and Elisabeth Haas (died 1861). He graduated from the Kamienna Góra gymnasium and joined the University of Wrocław. He received a PhD in 1882 studying under Heinrich Göppert and moved to Kiel and habilitated in 1886 for studies on the Cyperaceae. He served as an assistant at the Botanical Garden and moved to Berlin in 1889 where he worked with Adolf Engler. In 1893 he became the chair of botany at Wrocław. He became a professor of botany and zoolog ...
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Succulent
In botany, succulent plants, also known as succulents, are plants with parts that are thickened, fleshy, and engorged, usually to retain water in arid climates or soil conditions. The word ''succulent'' comes from the Latin word ''sucus'', meaning "juice" or "sap". Succulent plants may store water in various structures, such as leaves and stems. The water content of some succulent organs can get up to 90–95%, such as '' Glottiphyllum semicyllindricum'' and '' Mesembryanthemum barkleyii''. Some definitions also include roots, thus geophytes that survive unfavorable periods by dying back to underground storage organs may be regarded as succulents. The habitats of these water-preserving plants are often in areas with high temperatures and low rainfall, such as deserts, but succulents may be found even in alpine ecosystems growing in rocky soil. Succulents are characterized by their ability to thrive on limited water sources, such as mist and dew, which makes them equipped to s ...
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Spurge
''Euphorbia'' is a very large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae. "Euphorbia" is sometimes used in ordinary English to collectively refer to all members of Euphorbiaceae (in deference to the type genus), not just to members of the genus. Euphorbias range from tiny annual plants to large and long-lived trees. The genus has roughly 2,000 members, making it one of the largest genera of flowering plants. It also has one of the largest ranges of chromosome counts, along with ''Rumex'' and ''Senecio''. ''Euphorbia antiquorum'' is the type species for the genus ''Euphorbia''. It was first described by Carl Linnaeus in 1753 in ''Species Plantarum''. Some euphorbias are widely available commercially, such as poinsettias at Christmas. Some are commonly cultivated as ornamentals, or collected and highly valued for the aesthetic appearance of their unique floral structures, such as the crown of thorns plant (''Euphorbia milii''). ...
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Nigeria
Nigeria ( ), , ig, Naìjíríyà, yo, Nàìjíríà, pcm, Naijá , ff, Naajeeriya, kcg, Naijeriya officially the Federal Republic of Nigeria, is a country in West Africa. It is situated between the Sahel to the north and the Gulf of Guinea to the south in the Atlantic Ocean. It covers an area of , and with a population of over 225 million, it is the most populous country in Africa, and the world's sixth-most populous country. Nigeria borders Niger in the north, Chad in the northeast, Cameroon in the east, and Benin in the west. Nigeria is a federal republic comprising of 36 states and the Federal Capital Territory, where the capital, Abuja, is located. The largest city in Nigeria is Lagos, one of the largest metropolitan areas in the world and the second-largest in Africa. Nigeria has been home to several indigenous pre-colonial states and kingdoms since the second millennium BC, with the Nok civilization in the 15th century BC, marking the first ...
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Latex
Latex is an emulsion (stable dispersion) of polymer microparticles in water. Latexes are found in nature, but synthetic latexes are common as well. In nature, latex is found as a milky fluid found in 10% of all flowering plants (angiosperms). It is a complex emulsion that coagulates on exposure to air, consisting of proteins, alkaloids, starches, sugars, oils, tannins, resins, and gums. It is usually exuded after tissue injury. In most plants, latex is white, but some have yellow, orange, or scarlet latex. Since the 17th century, latex has been used as a term for the fluid substance in plants, deriving from the Latin word for "liquid". It serves mainly as defense against herbivorous insects. Latex is not to be confused with plant sap; it is a distinct substance, separately produced, and with different functions. The word latex is also used to refer to natural latex rubber, particularly non-vulcanized rubber. Such is the case in products like latex gloves, latex condoms ...
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Berom People
The Berom (sometimes also spelt as Birom) is the largest autochthonous ethnic group in Plateau State, central Nigeria. Covering about four local government areas, which include Jos North, Jos South, Barkin Ladi (Gwol) and Riyom, Berom are also found in some southern Kaduna State local government areas like Fadan Karshe with Berom settlers tracing their origins to Za'ang (Zawan) a Berom district on the Jos Plateau. They emigrated during the British Colonial Government of Nigeria. The Berom speak the Berom language, which belongs to the Plateau branch of Benue–Congo, a subfamily of the large Niger–Congo language family. It is not related to the Hausa language (which belongs to the Afro-Asiatic family) or other Afro-Asiatic languages of Plateau State, which are Chadic languages. Culture The Berom people have a rich cultural heritage. They celebrate the Nzem Berom festival annually in March or April. Other festivals include Nzem Tou Chun (worongchun) and Wusal Berom. Its o ...
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Witchcraft
Witchcraft traditionally means the use of magic or supernatural powers to harm others. A practitioner is a witch. In medieval and early modern Europe, where the term originated, accused witches were usually women who were believed to have used malevolent magic against their own community, and often to have communed with evil beings. It was thought witchcraft could be thwarted by protective magic or counter-magic, which could be provided by cunning folk or folk healers. Suspected witches were also intimidated, banished, attacked or killed. Often they would be formally prosecuted and punished, if found guilty or simply believed to be guilty. European witch-hunts and witch trials in the early modern period led to tens of thousands of executions. In some regions, many of those accused of witchcraft were folk healers or midwives. European belief in witchcraft gradually dwindled during and after the Age of Enlightenment. Contemporary cultures that believe in magic and the superna ...
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Resiniferatoxin
Resiniferatoxin (RTX) is a naturally occurring chemical found in resin spurge (''Euphorbia resinifera''), a cactus-like plant commonly found in Morocco, and in ''Euphorbia poissonii'' found in northern Nigeria.''Euphorbia poissonii''
in BoDD – Botanical Dermatology Database
It is a potent functional analog of , the active ingredient in .


Biological activity

R ...
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Tinyatoxin
Tinyatoxin (TTX or TTN) is an analog of the neurotoxin resiniferatoxin. It occurs naturally in ''Euphorbia poissonii''.''Euphorbia poissonii''
in BoDD – Botanical Dermatology Database
It is a neurotoxin that acts via full agonism of the receptors of sensory nerves. Tinyatoxin has a potential for pharmaceutical uses similar to uses of . Tinyatoxin is about one third as strong as

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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ...
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Capsaicin
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy?
Talk of the Nation, 15 August 2008.
Pure capsaicin is a , colorless, highly

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Nerve
A nerve is an enclosed, cable-like bundle of nerve fibers (called axons) in the peripheral nervous system. A nerve transmits electrical impulses. It is the basic unit of the peripheral nervous system. A nerve provides a common pathway for the electrochemical nerve impulses called action potentials that are transmitted along each of the axons to peripheral organs or, in the case of sensory nerves, from the periphery back to the central nervous system. Each axon, within the nerve, is an extension of an individual neuron, along with other supportive cells such as some Schwann cells that coat the axons in myelin. Within a nerve, each axon is surrounded by a layer of connective tissue called the endoneurium. The axons are bundled together into groups called fascicles, and each fascicle is wrapped in a layer of connective tissue called the perineurium. Finally, the entire nerve is wrapped in a layer of connective tissue called the epineurium. Nerve cells (often called neurons) are f ...
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