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Effects Of Sleep Deprivation In Space
Studies, which include laboratory investigations (Category I) and field evaluations (Category II and Category III) of population groups that are analogous to astronauts (e.g., medical and aviation personnel), provide compelling evidence that working long shifts for extended periods of time contributes to sleep deprivation and can cause performance decrements, health problems, and other detrimental consequences, including accidents, that can affect both the worker and others. Performance errors relative to sleep loss and extended wakefulness A meta-analysis (Category I) that was conducted by Pilcher and Huffcutt examined data that were drawn from 19 research studies to characterize the effects of sleep deprivation on specific types of human performance. Motor skills, cognitive skills, and mood were assessed in terms of: partial sleep derivation (also known as sleep deprivation), which is defined as fewer than 5 hours of sleep in a 24-hour period for 1 or more days; short-term tota ...
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NASA Categories Of Evidence
NASA Categories of Evidence comprise a matrix or scale denoting the sources of evidence provided in the Human Research Program's various evidence reports, and thus potentially their probative value and efficacy. Authors in the Program were urged to label their evidence according to whether it was based on controlled experiments, observation, or expert opinion. References

Human spaceflight NASA {{NASA-stub ...
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Melatonin
Melatonin is a natural product found in plants and animals. It is primarily known in animals as a hormone released by the pineal gland in the brain at night, and has long been associated with control of the sleep–wake cycle. In vertebrates, melatonin is involved in synchronizing circadian rhythms, including sleep–wake timing and blood pressure regulation, and in control of seasonal rhythmicity including reproduction, fattening, moulting and hibernation. Many of its effects are through activation of the melatonin receptors, while others are due to its role as an antioxidant. In plants, it functions to defend against oxidative stress. It is also present in various foods. Melatonin was discovered in 1958. In addition to its role as a natural hormone, melatonin is used as a dietary supplement and medication in the treatment of sleep disorders such as insomnia and circadian rhythm sleep disorders; for information on melatonin as a supplement and medication, see the me ...
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Space Medicine
Space medicine is the practice of medicine on astronauts in outer space whereas astronautical hygiene is the application of science and technology to the prevention or control of exposure to the hazards that may cause astronaut ill health. Both these sciences work together to ensure that astronauts work in a safe environment. The main objective is to discover how well and for how long people can survive the extreme conditions in space, and how fast they can adapt to the Earth's environment after returning from their voyage. Medical consequences such as possible blindness and bone loss have been associated with human spaceflight. In October 2015, the NASA Office of Inspector General issued a health hazards report related to space exploration, including a human mission to Mars. History Hubertus Strughold (1898–1987), a former Nazi physician and physiologist, was brought to the United States after World War II as part of Operation Paperclip. He first coined the term "spa ...
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Skylab 4
Skylab 4 (also SL-4 and SLM-3) was the third crewed Skylab mission and placed the third and final crew aboard the first American space station. The mission began on November 16, 1973, with the launch of Gerald P. Carr, Edward Gibson, and William R. Pogue in an Apollo command and service module on a Saturn IB rocket from the Kennedy Space Center, Florida, and lasted 84 days, one hour and 16 minutes. A total of 6,051 astronaut-utilization hours were tallied by the Skylab 4 astronauts performing scientific experiments in the areas of medical activities, solar observations, Earth resources, observation of the Comet Kohoutek and other experiments. The crewed Skylab missions were officially designated Skylab 2, 3, and 4. Miscommunication about the numbering resulted in the mission emblems reading "Skylab I", "Skylab II", and "Skylab 3" respectively. Launch NASA's launch center was located in an area called Cape Kennedy since May 15, 1964. Cape Kennedy was renamed Cape Canavera ...
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Sleep Deprivation
Sleep deprivation, also known as sleep insufficiency or sleeplessness, is the condition of not having adequate duration and/or quality of sleep to support decent alertness, performance, and health. It can be either chronic or acute and may vary widely in severity. Acute sleep deprivation is when an individual sleeps less than usual or does not sleep at all for a short period of time – usually lasting one to two days. Chronic sleep deprivation means when an individual routinely sleeps less than an optimal amount for ideal functioning. Chronic sleep deficiency is often confused with the term insomnia. Although both chronic sleep deficiency and insomnia share decreased quantity and/or quality of sleep as well as impaired function, their difference lies in the ability to fall asleep. Sleep deprived individuals are able to fall asleep rapidly when allowed but those with insomnia have difficulty falling asleep. The average adult needs seven or more hours of sleep per night to mainta ...
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Shift Work Sleep Disorder
Shift work sleep disorder (SWSD) is a circadian rhythm sleep disorder characterized by insomnia, excessive sleepiness, or both affecting people whose work hours overlap with the typical sleep period. Insomnia can be the difficulty to fall asleep or to wake up before the individual has slept enough. About 20% of the working population participates in shift work. SWSD commonly goes undiagnosed, so it's estimated that 10–40% of shift workers have SWSD. The excessive sleepiness appears when the individual has to be productive, awake and alert. Both symptoms are predominant in SWSD. There are numerous shift work schedules, and they may be permanent, intermittent, or rotating; consequently, the manifestations of SWSD are quite variable. Most people with different schedules than the ordinary one (from 8 AM to 6 PM) might have these symptoms but the difference is that SWSD is continual, long-term, and starts to interfere with the individual's life. Health effects There have been man ...
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Effects Of Sleep Deprivation On Cognitive Performance
It has been estimated that over 20% of adults suffer from some form of sleep deprivation. Insomnia and sleep deprivation are common symptoms of depression, and can be an indication of other mental disorders.Diagnostic and statistical manual of mental disorders: DSM-IV. American Psychiatric Association, Washington, DC: 1994 The consequences of not getting enough sleep could have dire results; not only to the health, cognition, energy level and the mood of the individual, but also to those around them as sleep deprivation increases the risk of human-error related accidents, especially with vigilance-based tasks involving technology. Attention Neural substrates The parietal lobes of the brain are largely involved in attention. Lesions to this region of the brain in humans result in difficulty or inability to attend to events that are contralateral to the lesioned hemisphere. Those with lesions to the posterior parietal lobe have little to no difficulty shifting attention to ...
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Growth Hormone
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A recombinant form of hGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. In the United States, it is only available legally from pharmacies by prescription from a licensed health care provider. In recent years in the United States, some health care providers are prescribing gr ...
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Circadian Rhythm
A circadian rhythm (), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (i.e., endogenous) and responds to the environment ( entrained by the environment). These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in animals, plants, fungi and cyanobacteria. The term ''circadian'' comes from the Latin ''circa'', meaning "approximately", and ''dies'', meaning "day". Processes with 24-hour cycles are more generally called diurnal rhythms; diurnal rhythms should not be called circadian rhythms unless they can be confirmed as endogenous, and not environmental. Although circadian rhythms are endogenous, they are adjusted to the local environment by external cues called zeitgebers (German for "time givers"), which include light, temperature and redox cycles. In clinical settings, an abnormal circadian rhythm in h ...
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Sleep Deprivation
Sleep deprivation, also known as sleep insufficiency or sleeplessness, is the condition of not having adequate duration and/or quality of sleep to support decent alertness, performance, and health. It can be either chronic or acute and may vary widely in severity. Acute sleep deprivation is when an individual sleeps less than usual or does not sleep at all for a short period of time – usually lasting one to two days. Chronic sleep deprivation means when an individual routinely sleeps less than an optimal amount for ideal functioning. Chronic sleep deficiency is often confused with the term insomnia. Although both chronic sleep deficiency and insomnia share decreased quantity and/or quality of sleep as well as impaired function, their difference lies in the ability to fall asleep. Sleep deprived individuals are able to fall asleep rapidly when allowed but those with insomnia have difficulty falling asleep. The average adult needs seven or more hours of sleep per night to mainta ...
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HHPS Figure 3-3
Hazard symbols or warning symbols are recognisable symbols designed to warn about hazardous or dangerous materials, locations, or objects, including electric currents, poisons, and radioactivity. The use of hazard symbols is often regulated by law and directed by standards organizations. Hazard symbols may appear with different colors, backgrounds, borders, and supplemental information in order to specify the type of hazard and the level of threat (for example, toxicity classes). Warning symbols are used in many places in lieu of or addition to written warnings as they are quickly recognized (faster than reading a written warning) and more commonly understood (the same symbol can be recognized as having the same meaning to speakers of different languages). List of common symbols Tape with yellow and black diagonal stripes is commonly used as a generic hazard warning. This can be in the form of barricade tape, or as a self-adhesive tape for marking floor areas and the l ...
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HHPS Figure 3-2
Hazard symbols or warning symbols are recognisable symbols designed to warn about hazardous or dangerous materials, locations, or objects, including electric currents, poisons, and radioactivity. The use of hazard symbols is often regulated by law and directed by standards organizations. Hazard symbols may appear with different colors, backgrounds, borders, and supplemental information in order to specify the type of hazard and the level of threat (for example, toxicity classes). Warning symbols are used in many places in lieu of or addition to written warnings as they are quickly recognized (faster than reading a written warning) and more commonly understood (the same symbol can be recognized as having the same meaning to speakers of different languages). List of common symbols Tape with yellow and black diagonal stripes is commonly used as a generic hazard warning. This can be in the form of barricade tape, or as a self-adhesive tape for marking floor areas and the l ...
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