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Embraer E-Jet E2 Family
The Embraer E-Jet E2 family are medium-range jet airliners developed by Embraer, succeeding the original E-Jet. The program was launched at the Paris Air Show in 2013. The first variant, the E190-E2, took its first flight on 23 May 2016 and was certified on 28 February 2018 before entering service with Widerøe on 24 April. The three twinjet variants share the same four-abreast narrow-body fuselage with different lengths and three different new wings, Pratt & Whitney PW1000G turbofans in two sizes, fly-by-wire controls with new avionics, and an updated cabin. Development Background In 2010, it appeared possible Embraer could directly challenge the Bombardier CSeries (now A220) with a clean-sheet five-abreast design for 100 to 150 passengers. When that market segment grew more competitive with the announcement of the Airbus A320neo and the Boeing 737 MAX, Embraer had instead committed to producing new variants of its E-Jet family of regional jets by the time of the November ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
E2 Series Shinkansen
The is a Japanese high-speed Shinkansen train type operated by East Japan Railway Company (JR East) on the Tohoku Shinkansen high-speed lines in Japan since 1997. They are formed in 8- and 10-car sets. The 8-car sets were used on the Hokuriku Shinkansen, and the 10-car sets are on Tohoku Shinkansen services. The 10-car sets can be coupled to E3 series sets using couplers hidden behind retracting nose doors. They operate at a maximum speed of on the Tohoku Shinkansen. A total of 502 vehicles (14 8-car "N" sets and 39 10-car "J" sets) were built between 1997 and 2010, with the first withdrawals commencing in late 2013. Operations Tohoku Shinkansen * ''Yamabiko'' * ''Nasuno'' Past operations Hokuriku Shinkansen * '' Asama'' (1 October 1997 - 31 March 2017) Joetsu Shinkansen * '' Asahi'' * '' Toki'' * '' Tanigawa'' Variants * E2 series 8-car "N" sets * E2' series 10-car "J" sets * E2-1000 series 10-car "J" sets 8-car "N" sets The fleet of thirteen "N" sets was constructed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prostaglandin E2
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open. In babies it is used in those with congenital heart defects until surgery can be carried out. It is also used to manage gestational trophoblastic disease. It may be used within the vagina or by injection into a vein. PGE2 synthesis within the body begins with the activation of arachidonic acid (AA) by the enzyme phospholipase A2. Once activated, AA is oxygenated by cyclooxygenase (COX) enzymes to form prostaglandin endoperoxides. Specifically, prostaglandin G2 (PGG2) is modified by the peroxidase moiety of the COX enzyme to produce prostaglandin H2 (PGH2) which is then converted to PGE2. Common side effects of PGE2 include nausea, vomiting, diarrhea, fever, and excessive uterine cont ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ubiquitin-conjugating Enzyme
Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ''ubiquitin-carrier enzymes'', perform the second step in the ubiquitination reaction that targets a protein for degradation via the proteasome. The ubiquitination process covalently attaches ubiquitin, a short protein of 76 amino acids, to a lysine residue on the target protein. Once a protein has been tagged with one ubiquitin molecule, additional rounds of ubiquitination form a polyubiquitin chain that is recognized by the proteasome's 19S regulatory particle, triggering the ATP-dependent unfolding of the target protein that allows passage into the proteasome's 20S core particle, where proteases degrade the target into short peptide fragments for recycling by the cell. Relationships A ubiquitin-activating enzyme, or E1, first activates the ubiquitin by covalently attaching the molecule to its active site cysteine residue. The activated ubiquitin is then transferred to an E2 cysteine. Once conjugated to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Everything2
Everything2 (styled Everything2 or E2 for short) is a collaborative Web-based community consisting of a database of interlinked user-submitted written material. E2 is moderated for quality, but has no formal policy on subject matter. Writing on E2 covers a wide range of topics and genres, including encyclopedic articles, diary entries (known as "daylogs"), poetry, humor, and fiction. History The predecessor of E2 was a similar database called Everything (later labeled "Everything1" or "E1") which was started around March 1998 by Nathan Oostendorp and was initially closely aligned with and promoted by the technology-related news website Slashdot (by virtue of various key principals having attended the Holland Christian High School), even sharing (at the time) some administrators. The Everything2 software offered vastly more features, and the Everything1 data was twice incorporated into E2: once on November 13, 1999, and again in January 2000. The Everything2 server used to be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LB&SCR E2 Class
The London, Brighton and South Coast Railway (LB&SCR) E2 class was a class of 0-6-0 T steam locomotives designed by Lawson Billinton, intended for shunting and short distance freight trains. Ten examples were built between 1913 and 1916, and were withdrawn from service and scrapped between 1961 and 1963. Background By 1910 many of the Stroudley E1 class locomotives were worn out or inadequate for the heavier duties required of them. D. E. Marsh intended to rebuild some examples with a larger boiler, but only one E1X rebuild had been completed by the time of his unexpected retirement. Marsh's successor Billinton reversed this policy and instead ordered five new, more powerful locomotives from Brighton works. The new class included several features found on other LB&SCR classes including an I2 class boiler. They were delivered between June 1913 and January 1914. Second Series The new design was judged to be successful, except that they were found to have inadequate water sup ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dihydrolipoyl Transacetylase
Dihydrolipoyl transacetylase (or dihydrolipoamide acetyltransferase) is an enzyme component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for the pyruvate decarboxylation step that links glycolysis to the citric acid cycle. This involves the transformation of pyruvate from glycolysis into acetyl-CoA which is then used in the citric acid cycle to carry out cellular respiration. There are three different enzyme components in the pyruvate dehydrogenase complex. Pyruvate dehydrogenase (EC 1.2.4.1) is responsible for the oxidation of pyruvate, dihydrolipoyl transacetylase (this enzyme; EC 2.3.1.12) transfers the acetyl group to coenzyme A (CoA), and dihydrolipoyl dehydrogenase (EC 1.8.1.4) regenerates the lipoamide. Because dihydrolipoyl transacetylase is the second of the three enzyme components participating in the reaction mechanism for conversion of pyruvate into acetyl CoA, it is sometimes referred to as E2. In humans, dihydrol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elimination Reaction
An elimination reaction is a type of organic reaction in which two substituents are removed from a molecule in either a one- or two-step mechanism. The one-step mechanism is known as the E2 reaction, and the two-step mechanism is known as the E1 reaction. The numbers refer not to the number of steps in the mechanism, but rather to the kinetics of the reaction: E2 is bimolecular (second-order) while E1 is unimolecular (first-order). In cases where the molecule is able to stabilize an anion but possesses a poor leaving group, a third type of reaction, E1CB, exists. Finally, the pyrolysis of xanthate and acetate esters proceed through an "internal" elimination mechanism, the Ei mechanism. E2 mechanism The E2 mechanism, where E2 stands for bimolecular elimination, involves a one-step mechanism in which ''carbon-hydrogen'' and ''carbon-halogen'' bonds break to form a double bond (''C=C Pi bond''). The specifics of the reaction are as follows: * E2 is a single step elimination, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EMC E2
The EMC E2 was an American passenger-train diesel locomotive which as a single unit developed , from two (2) prime movers. These locomotives were typically operated as a unit set ( A - B - B) or ( A - B - A); where the three unit lashup developed 5400 horsepower. This was almost the ideal horsepower required () for the tonnage of a 15 - 18 car passenger train, operated over the ruling grades of virtually all of the mileage between major American cities. The units were of the A1A-A1A wheel arrangement, and manufactured by Electro-Motive Corporation (EMC), later Electro-Motive Diesel (EMD) of La Grange, Illinois. Two sets (each of three units, A-B-B) () were produced in 1937 for named passenger trains; the first set (SF-1, SF-2, and SF-3) for the '' City of San Francisco''. These motive-power sets were jointly owned and operated by the Union Pacific Railroad, the Chicago and North Western Railway, and the Southern Pacific Railroad. The second A-B-B set (LA-1, LA-2, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tungsten E2
The Tungsten series was Palm, Inc.'s line of business-class Palm OS-based PDAs. Details The Tungsten series was introduced in October 2002, created as a "prosumer" line priced at $199 to $300 to compete with the popular Sony Clie and Windows Mobile PDAs. The first device in the line is the Tungsten T, making it the first Palm PDA to be labeled with a letter rather than a number and to run Palm OS 5. All of the Tungsten PDAs have a few attributes in common: * 65,536 color LCD touch screen with a minimum 320 x 320 pixel resolution * metal or metal-toned enclosure * available flip cover to protect the screen * Secure Digital (SD) card slot with SDIO for memory cards and accessories * no built-in camera All models except the Tungsten C, W, and E have built-in Bluetooth wireless capabilities, while the Tungsten C and TX feature built-in Wi-Fi connectivity. Furthermore, by using the optional Palm Wi-Fi Secure_Digital#SDIO_cards Card accessory, the T3, T5, and E2 can also gain Wi-F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Motorola ROKR E2
The Motorola ROKR (), the first version of which was informally known as the iTunes phone, was a series of mobile phones from Motorola, part of a 4LTR line developed before the spin out of Motorola Mobility. ROKR models were released starting in September 2005 and ending in 2009. They were notable for incorporating support of media player features. E1 Launched on September 7, 2005, in San Francisco, California, the E1 is the first phone to be integrated with Apple's iTunes music player, the next phone being the first iPhone in 2007. The phone had been widely expected, with technology sites reporting on collaborations between Motorola and Apple as far back as December 2004. Description and acceptance The ROKR E1 is a re-badged Motorola E398 candybar style phone (it was originally called the E790) with Apple-licensed technology to play back iTunes Music Store purchased music. It features a music player with an interface similar to that of Apple's iPod music players. Since h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Northrop Grumman E-2 Hawkeye
The Northrop Grumman E-2 Hawkeye is an American all-weather, carrier-capable tactical airborne early warning (AEW) aircraft. This twin-turboprop aircraft was designed and developed during the late 1950s and early 1960s by the Grumman Aircraft Company for the United States Navy as a replacement for the earlier, piston-engined E-1 Tracer, which was rapidly becoming obsolete. The aircraft's performance has been upgraded with the E-2B and E-2C versions, where most of the changes were made to the radar and radio communications due to advances in electronic integrated circuits and other electronics. The fourth major version of the Hawkeye is the E-2D, which first flew in 2007. The E-2 was the first aircraft designed specifically for its role, as opposed to a modification of an existing airframe, such as the Boeing E-3 Sentry. Variants of the Hawkeye have been in continuous production since 1960, giving it the longest production run of any carrier-based aircraft. The E-2 also received ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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