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Dinoxyline
Dinoxyline is a synthetic compound developed for scientific research, which acts as a potent full agonist at all five dopamine receptor Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through diffe ... subtypes. References Catechols D1-receptor agonists D2-receptor agonists D3 receptor agonists D4 receptor agonists D5 receptor agonists {{Nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synthetic Compound
In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, hydrogen cyanide), are not classified as organic compounds and are considered inorganic. Other than those just named, little consensus exists among chemists on precisely which carbon-containing compounds are excluded, making any rigorous definition of an organic compound elusive. Although organic compounds make up only a small percentage of Earth's crust, they are of central importance because all known life is based on organic compounds. Living t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist. Etymology From the Greek αγωνιστής (agōnistēs), contestant; champion; rival < αγων (agōn), contest, combat; exertion, struggle < αγω (agō), I lead, lead towards, conduct; drive Types of agonists can be activated by either endogenous agonists (such as |
Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. Subtypes The existence of multiple types of receptors for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catechols
Catechol ( or ), also known as pyrocatechol or 1,2-dihydroxybenzene, is a toxic organic compound with the molecular formula . It is the ''ortho'' isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amounts. It was first discovered by destructive distillation of the plant extract catechin. About 20,000 tonnes of catechol are now synthetically produced annually as a commodity organic chemical, mainly as a precursor to pesticides, flavors, and fragrances. Catechol occurs as feathery white crystals that are very rapidly soluble in water. Isolation and synthesis Catechol was first isolated in 1839 by Edgar Hugo Emil Reinsch (1809–1884) by distilling it from the solid tannic preparation catechin, which is the residuum of catechu, the boiled or concentrated juice of ''Mimosa catechu'' (''Acacia catechu''). Upon heating catechin above its decomposition point, a substance that Reinsch first named ''Brenz-Katechusäure'' (burned catechu acid) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D2-receptor Agonists
D, or d, is the fourth Letter (alphabet), letter in the Latin alphabet, used in the English alphabet, modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is English alphabet#Letter names, ''dee'' (pronounced ), plural ''dees''. History The Semitic languages, Semitic letter Daleth, Dāleth may have developed from the logogram for a fish or a door. There are many different Egyptian hieroglyphs that might have inspired this. In Semitic, Ancient Greek and Latin, the letter represented ; in the Etruscan alphabet the letter was archaic, but still retained (see letter B). The equivalent Greek letter is Delta, Delta (letter), Δ. Architecture The Lower case, minuscule (lower-case) form of 'd' consists of a lower-story left Typeface anatomy#Strokes, bowl and a Typeface anatomy#Strokes, stem ascender. It most likely developed by gradual variations on the upper case, majuscule (capital) form 'D', and today now composed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D3 Receptor Agonists
D3, D03, D.III, D III or D-3 may refer to: Transportation Roads * London Buses route D3, a Transport for London contracted bus route * D3 motorway (Czech Republic), a motorway in the Czech Republic * D3 road (Croatia), a state road in Croatia * D3 motorway (Slovakia), a motorway in northern Slovakia Aircraft * Albatros D.III, a 1916 German biplane fighter aircraft * Dewoitine D.3, a Dewoitine aircraft * Dunne D.3, a British Dunne aircraft * Fokker D.III, a 1916 German single-seat fighter aircraft * Mercedes D.III, a 1914 German 6-cylinder, liquid-cooled inline aircraft engine * Phönix D.III, a variant of the Austro-Hungarian First World War Phönix D.I biplane fighter * Pfalz D.III, a 1917 German fighter aircraft * Schütte-Lanz D.III, a 1918 German fighter aircraft prototype * Siemens-Schuckert D.III, a 1917 German prototype single-seat fighter aircraft Automobiles * Ford D3 platform, a full-size car automobile platform * Peugeot D3, a panel van manufactured from 1950 to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D4 Receptor Agonists
D4, D.IV, d4 or variants may refer to: Science and medicine * 22-Dihydroergocalciferol, vitamin D4 * D4-isoprostane, a type of isoprostane * ATC code D04, ''Antipruritics, including antihistamines, anesthetics, etc.'', a subgroup of the Anatomical Therapeutic Chemical Classification System * D04, Carcinoma in situ of skin ICD-10 code * Dopamine receptor D4, a human gene * Octamethylcyclotetrasiloxane, called D4 Mathematics * Dihedral group of order 4, otherwise known as the Klein four-group * Dihedral group of order 8, the symmetry group of a regular 4-gon * D4 (root system) Technology and computing * D4 (programming language), a programming language of the Dataphor system * D4 video connector, a type of analog video connector found on Japanese consumer electronics * D4 framing standard, a framing standard for traditional time-division multiplexing Aircraft * Albatros D.IV, a World War I experimental German fighter aircraft * Auster D.4, a 1960 two-seat British light a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
