Diiodothyronine
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Diiodothyronine
Diiodothyronine may refer to: * 3,3'-Diiodothyronine (3,3'-T2) * 3,5-Diiodothyronine 3,5-Diiodothyronine (3,5-T2) is an active thyroid hormone within the class of iodothyronines. It has two iodine atoms at positions 3 and 5 of its inner ring. Biological effects 3,5-T2 is an active thyroid hormone. It stimulates the TR-beta re ... (3,5-T2) Iodinated tyrosine derivatives Thyroid {{Short pages monitor ...
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3,5-Diiodothyronine
3,5-Diiodothyronine (3,5-T2) is an active thyroid hormone within the class of iodothyronines. It has two iodine atoms at positions 3 and 5 of its inner ring. Biological effects 3,5-T2 is an active thyroid hormone. It stimulates the TR-beta receptor for thyroid hormones and thus increases energy expenditure. It has agonistic (thyromimetic) effects at myocardial tissue and pituitary, which results in 3,5-T2 suppressing TSH release. 3,5-T2 is an allosteric regulator of the cytochrome c oxidase, the complex IV of the electron transport chain. It increases its activity by preventing the interaction of adenosine triphosphate Adenosine triphosphate (ATP) is an organic compound that provides energy to drive many processes in living cells, such as muscle contraction, nerve impulse propagation, condensate dissolution, and chemical synthesis. Found in all known forms o ... (ATP) as an allosteric inhibitor. Clinical significance In nonthyroidal illness syndrome 3,5-T2 concentra ...
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3,3'-Diiodothyronine
3,3'-Diiodothyronine, also known as 3,3'-T2, is a metabolite of thyroid hormone. It is formed from the breakdown of triiodothyronine Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Production of T3 and its prohormone thyroxine ( .... Levels can be affected in certain disease states. Reactions References {{DEFAULTSORT:Diiodothyronine, 3,3'- Iodinated tyrosine derivatives Human hormones Hormones of the hypothalamus-pituitary-thyroid axis Hormones of the thyroid gland Thyroid ...
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Iodinated Tyrosine Derivatives
Iodine is a chemical element with the symbol I and atomic number 53. The heaviest of the stable halogens, it exists as a semi-lustrous, non-metallic solid at standard conditions that melts to form a deep violet liquid at , and boils to a violet gas at . The element was discovered by the French chemist Bernard Courtois in 1811 and was named two years later by Joseph Louis Gay-Lussac, after the Ancient Greek 'violet-coloured'. Iodine occurs in many oxidation states, including iodide (I−), iodate (), and the various periodate anions. It is the least abundant of the stable halogens, being the sixty-first most abundant element. As the heaviest essential mineral nutrient, iodine is required for the synthesis of thyroid hormones. Iodine deficiency affects about two billion people and is the leading preventable cause of intellectual disabilities. The dominant producers of iodine today are Chile and Japan. Due to its high atomic number and ease of attachment to organic compounds, i ...
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