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Diglycolic Acid
Diglycolic acid is an aliphatic dicarboxylic acid, its acidity is between the one of acetic acid and oxalic acid. It is formed in the oxidation of diethylene glycol in the body and can lead to severe complications with fatal outcome. Preparation Oxidation of diethylene glycol with concentrated nitric acid was described by A. Wurtz in 1861 In parallel, W. Heintz reported the synthesis of diglycolic acid from chloroacetic acid by heating with sodium hydroxide solution. In a version with barium hydroxide solution as an alkaline medium, diglycolic acid is obtained in 68% yield after acidification. The yields of the described reactions are unsatisfactory for use on a technical scale. The single-stage nitric acid process gives even in the presence of an oxidation catalyst ( vanadium(V)oxide) yields of only 58-60%. In a multi-stage process of nitric acid oxidation at 70 °C and multiple crystallization steps, evaporation of the residues and return of the diethylene glycol-c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dicarboxylic Acid
In organic chemistry, a dicarboxylic acid is an organic compound containing two carboxyl groups (). The general molecular formula for dicarboxylic acids can be written as , where R can be aliphatic or aromatic. In general, dicarboxylic acids show similar chemical behavior and reactivity to monocarboxylic acids. Dicarboxylic acids are used in the preparation of copolymers such as polyamides and polyesters. The most widely used dicarboxylic acid in the industry is adipic acid, which is a precursor in the production of nylon. Other examples of dicarboxylic acids include aspartic acid and glutamic acid, two amino acids in the human body. The name can be abbreviated to diacid. Linear saturated dicarboxylic acids The general formula is .Boy Cornils, Peter Lappe "Dicarboxylic Acids, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry 2014, Wiley-VCH, Weinheim. The PubChem links gives access to more information on the compounds, including other names, ids, toxicity and safety ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
