Digitalis Grandiflora
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Digitalis Grandiflora
''Digitalis grandiflora'', the yellow foxglove, big-flowered foxglove, or large yellow foxglove, is a species of flowering plant in the genus ''Digitalis'', family Plantaginaceae (formerly Scrophulariaceae). It is native to southern Europe and Asia. In mountains it grows on warm, bushy slopes or areas left after logging. The Latin specific epithet ''grandiflora'' means “large flowered”. Description It is a herbaceous perennial growing from a short rootstock with fibrous roots. ''D. grandiflora'' has glossy green, veined leaves, whose flowering stem can reach a height of . The pale yellow bell-shaped flowers are spaced out on the stem, long and show a netted brown marking in their interior. In the wild plants bloom in June and July. Cultivation ''Digitalis grandiflora'' is long lived perennial, it has gained the Royal Horticultural Society's Award of Garden Merit. It is winter hardy is USDA zones 3 to 8 and grows best in moisture retentive, but well drained, organic soil ...
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Schynige Platte
The Schynige Platte (''Scheinige Platte'' on the old Siegfried Map) is a small mountain ridge and a viewpoint in the Bernese Highlands and belongs to the Schwarzhorn group. The mountain range consists of three peaks: Gumihorn (), Tuba (), and the closest summit next to the viewpoint, Geiss (). The viewpoint lies at an altitude of about , at the western end of a prominent ridge of the Schwarzhorn group, which separates the valley of the Schwarze Lütschine from Lake Brienz. It is notable for its hotel and, since 1893, its mountain railway, one of the highest in Switzerland. In good weather conditions there are views to many surrounding mountains, including the Eiger, Mönch, Jungfrau, and others giants of the Bernese Alps. Also, the town of Interlaken and the two great lakes of Thun and Brienz are visible to the north, lower. The area is accessible via the Schynige Platte railway, which runs from Wilderswil, where connection is made with Bernese Oberland railway trains fro ...
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Award Of Garden Merit
The Award of Garden Merit (AGM) is a long-established annual award for plants by the British Royal Horticultural Society (RHS). It is based on assessment of the plants' performance under UK growing conditions. History The Award of Garden Merit is a mark of quality awarded, since 1922, to garden plants (including trees, vegetables and decorative plants) by the United Kingdom, Royal Horticultural Society (RHS). Awards are made annually after plant trials intended to judge the plants' performance under UK growing conditions. Trials may last for one or more years, depending on the type of plant being analyzed, and may be performed at Royal Horticulture Society Garden in Wisley and other gardens or after observation of plants in specialist collections. Trial reports are made available as booklets and on the website. Awards are reviewed annually in case plants have become unavailable horticulturally, or have been superseded by better cultivars. Similar awards The award should not b ...
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Cardiac Glycoside
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for congestive heart failure and cardiac arrhythmias; however, their relative toxicity prevents them from being widely used. Most commonly found as secondary metabolites in several plants such as foxglove plants, these compounds nevertheless have a diverse range of biochemical effects regarding cardiac cell function and have also been suggested for use in cancer treatment. Classification General structure The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar (glycoside) and an R group. The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity. Cardiac glyco ...
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Digoxin
Digoxin (better known as Digitalis), sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is one of the oldest medications used in the field of cardiology. It works by increasing myocardial contractility, increasing stroke volume and blood pressure, reducing heart rate, and somewhat extending the time frame of the contraction. Digoxin is taken by mouth or by injection into a vein. Digoxin has a half life of approximately 36 hours given at average doses in patients with normal renal function. It is excreted mostly unchanged in the urine. Common side effects include breast enlargement with other side effects generally due to an excessive dose. These side effects may include loss of appetite, nausea, trouble seeing, confusion, and an irregular heartbeat. Greater care is required in older people and those with poor kidney function. ...
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Digitoxin
Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting. Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in patients with poor or erratic kidney function. While several controlled trials have shown digoxin to be effective in a proportion of patients treated for heart failure, the evidence base for digitoxin is not as strong, although it is presumed to be similarly effective. Medical uses Digitoxin is used for the treatment of heart failure, especially in people with impaired kidney function. It is also used to treat certain kinds of heart arrhythmia, such as atrial fibrillation. Contraindications Contraindications include * problems with the heart rhythm, such as severe bradycardia (slow heartbeat), ventricular tachycardia (fast heartbeat c ...
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Cardenolide
A cardenolide is a type of steroid. Many plants contain derivatives, collectively known as cardenolides, including many in the form of cardenolide glycosides (cardenolides that contain structural groups derived from sugars). Cardenolide glycosides are often toxic; specifically, they are heart-arresting. Cardenolides are toxic to animals through inhibition of the enzyme Na+/K+‐ATPase, which is responsible for maintaining the sodium and potassium ion gradients across the cell membranes. Etymology The term derives from ''card-'' "heart" (from Greek καρδία ''kardiā'') and the suffix ''-enolide'', referring to the lactone ring at C17. Cardenolides are a class of steroids (or aglycones if viewed as cardiac glycoside constituents), and cardenolides are a subtype of this class (see MeSH D codes list). Structure Cardenolides are C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone (specifically a butenolide) at C-17. They are aglycone constituents o ...
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Digitalis Purpurea
''Digitalis purpurea'', the foxglove or common foxglove, is a poisonous species of flowering plant in the plantain family Plantaginaceae, native to and widespread throughout most of temperate Europe. It has also naturalised in parts of North America and some other temperate regions. The plant is a popular garden subject, with many cultivars available. It is the original source of the heart medicine digoxin (also called digitalis or digitalin). This biennial plant grows as a rosette of leaves in the first year after sowing, before flowering and then dying in the second year (i.e. it is monocarpic). It generally produces enough seeds, however, so that new plants will continue to grow in a garden setting. Description ''Digitalis purpurea'' is an herbaceous biennial or short-lived perennial plant. The leaves are spirally arranged, simple, long and broad, and are covered with gray-white pubescent and glandular hairs, imparting a woolly texture. The foliage forms a tight rosette at ...
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Digitalis × Fulva
''Digitalis'' × ''fulva'', the strawberry foxglove, is a fertile hybrid between ''Digitalis grandiflora'' and ''Digitalis purpurea''. Description This perennial herbaceous plant reaches an average a height of . The erect stems rise from a semi-evergreen basal rosette of soft leaves. It has typical tall spikes of large tubular flowers. The color ranges from strawberry pink (hence the common name) to mauve. The flowering period extends from late spring to early summer. It prefers neutral or mildly acidic substrate and rich, moist and regularly watered soil, in full sun or in partial shade. This plant, which is widely marketed in the UK under its synonym ''Digitalis'' × ''mertonensis'', has gained the Royal Horticultural Society The Royal Horticultural Society (RHS), founded in 1804 as the Horticultural Society of London, is the UK's leading gardening charity. The RHS promotes horticulture through its five gardens at Wisley (Surrey), Hyde Hall (Essex), Harlow Carr (Nor ...'s ...
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Royal Horticultural Society
The Royal Horticultural Society (RHS), founded in 1804 as the Horticultural Society of London, is the UK's leading gardening charity. The RHS promotes horticulture through its five gardens at Wisley (Surrey), Hyde Hall (Essex), Harlow Carr (North Yorkshire), Rosemoor (Devon) and Bridgewater (Greater Manchester); flower shows including the Chelsea Flower Show, Hampton Court Palace Flower Show, Tatton Park Flower Show and Cardiff Flower Show; community gardening schemes; Britain in Bloom and a vast educational programme. It also supports training for professional and amateur gardeners. the president was Keith Weed and the director general was Sue Biggs CBE. History Founders The creation of a British horticultural society was suggested by John Wedgwood (son of Josiah Wedgwood) in 1800. His aims were fairly modest: he wanted to hold regular meetings, allowing the society's members the opportunity to present papers on their horticultural activities and discoveries, to ...
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Philip Miller
Philip Miller FRS (1691 – 18 December 1771) was an English botanist and gardener of Scottish descent. Miller was chief gardener at the Chelsea Physic Garden for nearly 50 years from 1722, and wrote the highly popular ''The Gardeners Dictionary''. Life Born in Deptford or Greenwich, Miller was chief gardener at the Chelsea Physic Garden from 1722 until he was pressured to retire shortly before his death. According to the botanist Peter Collinson, who visited the physic garden in July 1764 and recorded his observation in his commonplace books, Miller "has raised the reputation of the Chelsea Garden so much that it excels all the gardens of Europe for its amazing variety of plants of all orders and classes and from all climates..." He wrote ''The Gardener's and Florists Dictionary or a Complete System of Horticulture'' (1724) and ''The Gardener's Dictionary containing the Methods of Cultivating and Improving the Kitchen Fruit and Flower Garden'', which first appeared in 1 ...
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Herbaceous Plant
Herbaceous plants are vascular plants that have no persistent wood, woody stems above ground. This broad category of plants includes many perennial plant, perennials, and nearly all Annual plant, annuals and Biennial plant, biennials. Definitions of "herb" and "herbaceous" The fourth edition of the ''Shorter Oxford English Dictionary'' defines "herb" as: #"A plant whose stem does not become woody and persistent (as in a tree or shrub) but remains soft and succulent, and dies (completely or down to the root) after flowering"; #"A (freq. aromatic) plant used for flavouring or scent, in medicine, etc.". (See: Herb) The same dictionary defines "herbaceous" as: #"Of the nature of a herb; esp. not forming a woody stem but dying down to the root each year"; #"BOTANY Resembling a leaf in colour or texture. Opp. Glossary of botanical terms#scarious, scarious". Botanical sources differ from each other on the definition of "herb". For instance, the Hunt Institute for Botanical Documentatio ...
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Binomial Nomenclature
In taxonomy, binomial nomenclature ("two-term naming system"), also called nomenclature ("two-name naming system") or binary nomenclature, is a formal system of naming species of living things by giving each a name composed of two parts, both of which use Latin grammatical forms, although they can be based on words from other languages. Such a name is called a binomial name (which may be shortened to just "binomial"), a binomen, name or a scientific name; more informally it is also historically called a Latin name. The first part of the name – the '' generic name'' – identifies the genus to which the species belongs, whereas the second part – the specific name or specific epithet – distinguishes the species within the genus. For example, modern humans belong to the genus ''Homo'' and within this genus to the species ''Homo sapiens''. ''Tyrannosaurus rex'' is likely the most widely known binomial. The ''formal'' introduction of this system of naming species is credit ...
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