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DeLuca Biochemistry Building
The Hector F. DeLuca Biochemistry Building, originally known as the Agricultural Chemistry Building, is a historic structure on the campus of the University of Wisconsin–Madison. It was the site of the discovery of vitamins A and B, as well as the development of vitamin D processing. History The building was part of the expansion of the College of Agriculture undertaken by Edwin B. Hart. Hart assumed leadership of the department in 1906. The next year, Stephen Moulton Babcock and Elmer McCollum began the single-grain experiment, which fostered the development of agricultural chemistry at Wisconsin. The experiment continued in the Agricultural Chemistry Building when it was built in 1912 and was expended to identify the key elements in nutrition. With . In 1913, McCollum identified a molecule in egg yolks, vitamin A. The discovery was consistent with the nutrition element proposed by Frederick Gowland Hopkins a year before. The experiment continued, and in 1915, McCollum ide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Madison, Wisconsin
Madison is the county seat of Dane County and the capital city of the U.S. state of Wisconsin. As of the 2020 census the population was 269,840, making it the second-largest city in Wisconsin by population, after Milwaukee, and the 80th-largest in the U.S. The city forms the core of the Madison Metropolitan Area which includes Dane County and neighboring Iowa, Green, and Columbia counties for a population of 680,796. Madison is named for American Founding Father and President James Madison. The city is located on the traditional land of the Ho-Chunk, and the Madison area is known as ''Dejope'', meaning "four lakes", or ''Taychopera'', meaning "land of the four lakes", in the Ho-Chunk language. Located on an isthmus and lands surrounding four lakes—Lake Mendota, Lake Monona, Lake Kegonsa and Lake Waubesa—the city is home to the University of Wisconsin–Madison, the Wisconsin State Capitol, the Overture Center for the Arts, and the Henry Vilas Zoo. Madison is ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen due to a lower than normal number of red blood cells, or a reduction in the amount of hemoglobin. When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Symptoms of anemia depend on how quickly hemoglobin decreases. Additional symptoms may occur depending on the underlying cause. Preoperative anemia can increase the risk of needing a blood transfusion following surgery. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Balustrade
A baluster is an upright support, often a vertical moulded shaft, square, or lathe-turned form found in stairways, parapets, and other architectural features. In furniture construction it is known as a spindle. Common materials used in its construction are wood, stone, and less frequently metal and ceramic. A group of balusters supporting a handrail, coping, or ornamental detail are known as a balustrade. The term baluster shaft is used to describe forms such as a candlestick, upright furniture support, and the stem of a brass chandelier. The term banister (also bannister) refers to a baluster or to the system of balusters and handrail of a stairway. It may be used to include its supporting structures, such as a supporting newel post. Etymology According to the ''Oxford English Dictionary'', "baluster" is derived through the french: balustre, from it, balaustro, from ''balaustra'', "pomegranate flower" rom a resemblance to the swelling form of the half-open flower (''illus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quoins
Quoins ( or ) are masonry blocks at the corner of a wall. Some are structural, providing strength for a wall made with inferior stone or rubble, while others merely add aesthetic detail to a corner. According to one 19th century encyclopedia, these imply strength, permanence, and expense, all reinforcing the onlooker's sense of a structure's presence. Stone quoins are used on stone or brick buildings. Brick quoins may appear on brick buildings, extending from the facing brickwork in such a way as to give the appearance of generally uniformly cut ashlar blocks of stone larger than the bricks. Where quoins are decorative and non-load-bearing a wider variety of materials is used, including timber, stucco, or other cement render. Techniques Ashlar blocks In a traditional, often decorative use, large rectangular ashlar stone blocks or replicas are laid horizontally at the corners. This results in an alternate, quoining pattern. Alternate cornerstones Courses of large and small c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pediment
Pediments are gables, usually of a triangular shape. Pediments are placed above the horizontal structure of the lintel, or entablature, if supported by columns. Pediments can contain an overdoor and are usually topped by hood moulds. A pediment is sometimes the top element of a portico. For symmetric designs, it provides a center point and is often used to add grandness to entrances. The tympanum, the triangular area within the pediment, is often decorated with a pedimental sculpture which may be freestanding or a relief sculpture. The tympanum may hold an inscription, or in modern times, a clock face. Pediments are found in ancient Greek architecture as early as 600 BC (e.g. the archaic Temple of Artemis). Variations of the pediment occur in later architectural styles such as Classical, Neoclassical and Baroque. Gable roofs were common in ancient Greek temples with a low pitch (angle of 12.5° to 16°). History The pediment is found in classical Greek temples, Et ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georgian Revival Architecture
*Colonial Revival architecture in the United States — ''primarily reviving the British Colonial period style''. ::*''See also: Spanish Colonial Revival architecture in the United States, and Dutch Colonial Revival architecture in the United States Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People E ....'' {{- Revival architecture in the United States Colonial Revival architecture Architecture in the United States by period or style ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henry Mall Historic District
The Henry Mall Historic District is a landscaped mall and the surrounding academic agriculture buildings on the University of Wisconsin–Madison campus, roughly laid out by architects Warren Laird and Paul Cret from 1906 to 1908, with buildings constructed from 1903 to 1961. With . In 1992 the district was added to the National Register of Historic Places. History The University of Wisconsin was created on paper in 1848, the same year that Wisconsin became a state. In 1850, before any building, a UW architect envisioned a mall running down the hill that would later be called Bascom Hill. The UW's oldest building, North Hall was built in 1851 near the top of that mall, and for fifty years most of the UW's construction was along the Bascom Hill mall. The UW curriculum initially focused on geography, English grammar, Latin and Greek. Chancellor Lathrop endorsed agricultural education already in 1851, but the state legislature didn't fund it. In 1857 Michigan did start a college of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hector F
In Greek mythology, Hector (; grc, Ἕκτωρ, Hektōr, label=none, ) is a character in Homer's Iliad. He was a Trojan prince and the greatest warrior for Troy during the Trojan War. Hector led the Trojans and their allies in the defense of Troy, killing countless Greek warriors. He was ultimately killed in single combat by Achilles, who later dragged his dead body around the city of Troy behind his chariot. Etymology In Greek, is a derivative of the verb ἔχειν ''ékhein'', archaic form * grc, ἕχειν, hékhein, label=none ('to have' or 'to hold'), from Proto-Indo-European *'' seɡ́ʰ-'' ('to hold'). , or as found in Aeolic poetry, is also an epithet of Zeus in his capacity as 'he who holds verything together. Hector's name could thus be taken to mean 'holding fast'. Description Hector was described by the chronicler Malalas in his account of the ''Chronography'' as "dark-skinned, tall, very stoutly built, strong, good nose, wooly-haired, good beard, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Register Of Historic Places
The National Register of Historic Places (NRHP) is the United States federal government's official list of districts, sites, buildings, structures and objects deemed worthy of preservation for their historical significance or "great artistic value". A property listed in the National Register, or located within a National Register Historic District, may qualify for tax incentives derived from the total value of expenses incurred in preserving the property. The passage of the National Historic Preservation Act (NHPA) in 1966 established the National Register and the process for adding properties to it. Of the more than one and a half million properties on the National Register, 95,000 are listed individually. The remainder are contributing resources within historic districts. For most of its history, the National Register has been administered by the National Park Service (NPS), an agency within the U.S. Department of the Interior. Its goals are to help property owners and inte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dicumarol
Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant drug that depletes stores of vitamin K (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Dicoumarol is a natural chemical substance of combined plant and fungal origin. It is a derivative of coumarin, a bitter-tasting but sweet-smelling substance made by plants that does not itself affect coagulation, but which is (classically) transformed in mouldy feeds or silages by a number of species of fungi, into active dicoumarol. Dicoumarol does affect coagulation, and was discovered in mouldy wet sweet-clover hay, as the cause of a naturally occurring bleeding disease in cattle. See warfarin for a more detailed discovery history. Identified in 1940, dicoumarol became the prototype of the 4-hydroxycoumarin anticoagulant drug class. Dicoumarol itself, for a short time, was employed as a medicinal anticoagulant drug, but since the mid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Paul Link
Karl Paul Gerhard Link (31 January 1901 – 21 November 1978) was an American biochemist best known for his discovery of the anticoagulant warfarin. Training and early career He was born in LaPorte, Indiana to a Lutheran minister of German descent as one of ten children. He was schooled locally, and attended the University of Wisconsin–Madison, where he studied agricultural chemistry at the College of Agriculture from 1918 to 1925, obtaining an MS in 1923 and a PhD in 1925. He was then chosen by the national Education Board for a postdoctoral scholarship, and relocated to Europe. He briefly worked with carbohydrate chemist Sir James Irvine at the University of St Andrews in Scotland and from 1926 in Graz, Austria with Fritz Pregl, inventor of microchemistry and Nobel Laureate. Finally he spent several months with organic chemist and future Nobel laureate Paul Karrer in the latter's lab in Zurich; during this period Link suffered from tuberculosis, requiring recuperation in Davo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pellagra
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to either sunlight or friction are typically affected first. Over time affected skin may become darker, stiffen, peel, or bleed. There are two main types of pellagra, primary and secondary. Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. Secondary pellagra is due to a poor ability to use the niacin within the diet. This can occur as a result of alcoholism, long-term diarrhea, carcinoid syndrome, Hartnup disease, and a number of medications such as isoniazid. Diagnosis is typically based on symptoms and may be assisted by urine testing. Treatment is with either niacin or nicotinamide supplementation. Improvements typically begin within a couple of days. General improvements in diet are also frequently recommended. Decreasing sun exposure via sunscreen and proper cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
