Davis's Law
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Davis's Law
Davis's law is used in anatomy and physiology to describe how soft tissue models along imposed demands. It is the corollary to Wolff's law, which applies to osseous tissue. It is a physiological principle stating that soft tissue heal according to the manner in which they are mechanically stressed. It is also an application of the Mechanostat model of Harold Frost which was originally developed to describe the adaptational response of bones; however – as outlined by Harold Frost himself – it also applies to fibrous collagenous connective tissues, such as ligaments, tendons and fascia.Frost, Harold "The physiology of cartilagenous, fibrous, and bony tissue. C.C. Thomas, 1972 The "stretch-hypertrophy rule" of that model states: "Intermittent stretch causes collagenous tissues to hypertrophy until the resulting increase in strength reduces elongation in tension to some minimum level". Similar to the behavior of bony tissues this adaptational response occurs only if the mechanical ...
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Soft Tissue
Soft tissue is all the tissue in the body that is not hardened by the processes of ossification or calcification such as bones and teeth. Soft tissue connects, surrounds or supports internal organs and bones, and includes muscle, tendons, ligaments, fat, fibrous tissue, lymph and blood vessels, fasciae, and synovial membranes. with :q=a_E_E_ \qquad Q=b_E_E_ quadratic forms of Green-Lagrange strains E_ and a_, b_ and c material constants. W is the strain energy function per volume unit, which is the mechanical strain energy for a given temperature. Isotropic simplification The Fung-model, simplified with isotropic hypothesis (same mechanical properties in all directions). This written in respect of the principal stretches (\lambda_i): :W = \frac\left (\lambda_1^2 + \lambda_2^2 + \lambda_3^2 - 3) + b\left( e^ -1 \right) \right/math> , where a, b and c are constants. Simplification for small and big stretches For small strains, the exponential term is very small, thus neg ...
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Tendon
A tendon or sinew is a tough, high-tensile-strength band of dense fibrous connective tissue that connects muscle to bone. It is able to transmit the mechanical forces of muscle contraction to the skeletal system without sacrificing its ability to withstand significant amounts of tension. Tendons are similar to ligaments; both are made of collagen. Ligaments connect one bone to another, while tendons connect muscle to bone. Structure Histologically, tendons consist of dense regular connective tissue. The main cellular component of tendons are specialized fibroblasts called tendon cells (tenocytes). Tenocytes synthesize the extracellular matrix of tendons, abundant in densely packed collagen fibers. The collagen fibers are parallel to each other and organized into tendon fascicles. Individual fascicles are bound by the endotendineum, which is a delicate loose connective tissue containing thin collagen fibrils and elastic fibres. Groups of fascicles are bounded by the epitenon, ...
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Musculoskeletal System
The human musculoskeletal system (also known as the human locomotor system, and previously the activity system) is an organ system that gives humans the ability to move using their muscular and skeletal systems. The musculoskeletal system provides form, support, stability, and movement to the body. It is made up of the bones of the skeleton, muscles, cartilage, tendons, ligaments, joints, and other connective tissue that supports and binds tissues and organs together. The musculoskeletal system's primary functions include supporting the body, allowing motion, and protecting vital organs. The skeletal portion of the system serves as the main storage system for calcium and phosphorus and contains critical components of the hematopoietic system. This system describes how bones are connected to other bones and muscle fibers via connective tissue such as tendons and ligaments. The bones provide stability to the body. Muscles keep bones in place and also play a role in the movement ...
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Hypertrophy
Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells. It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number.Updated by Linda J. Vorvick. 8/14/1Hyperplasia/ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally-induced proliferation and enlargement of the cells of the uterus during pregnancy. Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel). Gallery File:*+ * Photographic documentation on sexual education - Hypertrophy of bre ...
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Gastrocnemius Tendon
The gastrocnemius muscle (plural ''gastrocnemii'') is a superficial two-headed muscle that is in the back part of the lower leg of humans. It runs from its two heads just above the knee to the heel, a three joint muscle (knee, ankle and subtalar joints). The muscle is named via Latin, from Greek γαστήρ (''gaster'') 'belly' or 'stomach' and κνήμη (''knḗmē'') 'leg', meaning 'stomach of the leg' (referring to the bulging shape of the calf). Structure The gastrocnemius is located with the soleus in the posterior (back) compartment of the leg. The lateral head originates from the lateral condyle of the femur, while the medial head originates from the medial condyle of the femur. Its other end forms a common tendon with the soleus muscle; this tendon is known as the calcaneal tendon or Achilles tendon and inserts onto the posterior surface of the calcaneus, or heel bone. It is considered a superficial muscle as it is located directly under skin, and its shape may often be ...
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Micro-gravity
The term micro-g environment (also μg, often referred to by the term microgravity) is more or less synonymous with the terms ''weightlessness'' and ''zero-g'', but emphasising that g-forces are never exactly zero—just very small (on the International Space Station (ISS), for example, the small g-forces come from tidal effects, gravity from objects other than the Earth, such as astronauts, the spacecraft, and the Sun, air resistance, and astronaut movements that impart momentum to the space station). The symbol for microgravity, ''μg'', was used on the insignias of Space Shuttle flights STS-87 and STS-107, because these flights were devoted to microgravity research in low Earth orbit. The most commonly known microgravity environment can be found aboard the ISS which is located in low-earth orbit at an altitude of around 400 km, orbiting Earth approximately 15 times per day in what is considered free fall. The effects of free fall also enable the creation of short- ...
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Collagen Fiber
Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such as cartilage, bones, tendons, ligaments, and skin. Depending upon the degree of mineralization, collagen tissues may be rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue and accounts for 6% of the weight of the skeletal muscle tissue. The fibroblast is the most common cell tha ...
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Ultimate Tensile Strength
Ultimate tensile strength (UTS), often shortened to tensile strength (TS), ultimate strength, or F_\text within equations, is the maximum stress that a material can withstand while being stretched or pulled before breaking. In brittle materials the ultimate tensile strength is close to the yield point, whereas in ductile materials the ultimate tensile strength can be higher. The ultimate tensile strength is usually found by performing a tensile test and recording the engineering stress versus strain. The highest point of the stress–strain curve is the ultimate tensile strength and has units of stress. The equivalent point for the case of compression, instead of tension, is called the compressive strength. Tensile strengths are rarely of any consequence in the design of ductile members, but they are important with brittle members. They are tabulated for common materials such as alloys, composite materials, ceramics, plastics, and wood. Definition The ultimate tensile strength ...
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Deformation (mechanics)
In physics, deformation is the continuum mechanics transformation of a body from a ''reference'' configuration to a ''current'' configuration. A configuration is a set containing the positions of all particles of the body. A deformation can occur because of external loads, intrinsic activity (e.g. muscle contraction), body forces (such as gravity or electromagnetic forces), or changes in temperature, moisture content, or chemical reactions, etc. Strain is related to deformation in terms of ''relative'' displacement of particles in the body that excludes rigid-body motions. Different equivalent choices may be made for the expression of a strain field depending on whether it is defined with respect to the initial or the final configuration of the body and on whether the metric tensor or its dual is considered. In a continuous body, a deformation field results from a stress field due to applied forces or because of some changes in the temperature field of the body. The rel ...
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Young's Modulus
Young's modulus E, the Young modulus, or the modulus of elasticity in tension or compression (i.e., negative tension), is a mechanical property that measures the tensile or compressive stiffness of a solid material when the force is applied lengthwise. It quantifies the relationship between tensile/compressive stress \sigma (force per unit area) and axial strain \varepsilon (proportional deformation) in the linear elastic region of a material and is determined using the formula: E = \frac Young's moduli are typically so large that they are expressed not in pascals but in gigapascals (GPa). Example: * Silly Putty (increasing pressure: length increases quickly, meaning tiny E) * Aluminum (increasing pressure: length increases slowly, meaning high E) Higher Young's modulus corresponds to greater (lengthwise) stiffness. Although Young's modulus is named after the 19th-century British scientist Thomas Young, the concept was developed in 1727 by Leonhard Euler. The first experime ...
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Jacques Mathieu Delpech
Jacques Mathieu Delpech (1777 – 28 October 1832) was a French surgeon born in Toulouse. He earned his doctorate from the University of Paris in 1801 and spent the next several years as a teacher of anatomy in Toulouse. In 1812 he became a surgeon at Hôtel-Dieu Saint-Eloi in Montpellier, where he remained until his death in 1832. Delpech is best known for his work in orthopedics, and he established a clinic for orthopaedic diseases at Saint-Eloi. There he advocated a surgical process known as "tenotomy" to correct contracture abnormalities of the extremities. He was also a pioneer of skin grafting and rhinoplasty, and is credited for documenting the first rhinoplastic operation in France. Delpech died when he was shot by a patient on 28 October 1832. Partial list of works * ''Réflexions et observations anatomico-chirurgicales sur l’anévrisme'' (1809), (Translation of Antonio Scarpa's (1752–1832) work on aneurysms). * ''Précis des maladies chirurgicales'', (1815) * ''Co ...
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Corollary
In mathematics and logic, a corollary ( , ) is a theorem of less importance which can be readily deduced from a previous, more notable statement. A corollary could, for instance, be a proposition which is incidentally proved while proving another proposition; it might also be used more casually to refer to something which naturally or incidentally accompanies something else (e.g., violence as a corollary of revolutionary social changes). Overview In mathematics, a corollary is a theorem connected by a short proof to an existing theorem. The use of the term ''corollary'', rather than ''proposition'' or ''theorem'', is intrinsically subjective. More formally, proposition ''B'' is a corollary of proposition ''A'', if ''B'' can be readily deduced from ''A'' or is self-evident from its proof. In many cases, a corollary corresponds to a special case of a larger theorem, which makes the theorem easier to use and apply, even though its importance is generally considered to be secondary t ...
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