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David Klenerman
Sir David Klenerman (born 1959) is a British biophysical chemist and a professor of biophysical chemistry at the Department of Chemistry at the University of Cambridge and a Fellow of Christ's College, Cambridge. He is best known for his contribution in the field of next-generation sequencing of DNA (that subsequently resulted in Solexa, a high-speed DNA sequencing company that he co-founded), nanopipette-based scanning ion-conductance microscopy, and super-resolution microscopy. Education Klenerman was educated at the University of Cambridge where he was an undergraduate student of Christ's College, Cambridge and received his BA degree in 1982. He earned his PhD degree in chemistry in 1986 as a postgraduate student of Churchill College, Cambridge and was supervised by Ian William Murison Smith. Career and research After his doctorate, Klenerman went to Stanford University as a Fulbright scholar to work on high-overtone chemistry, with Richard Zare. After his postdoctoral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysical Chemistry
Biophysical chemistry is a physical science that uses the concepts of physics and physical chemistry for the study of biological systems. The most common feature of the research in this subject is to seek explanation of the various phenomena in biological systems in terms of either the molecules that make up the system or the supra-molecular structure of these systems. Techniques Biophysical chemists employ various techniques used in physical chemistry to probe the structure of biological systems. These techniques include spectroscopic methods such as nuclear magnetic resonance (NMR) and other techniques like X-ray diffraction and cryo-electron microscopy. An example of research in biophysical chemistry includes the work for which the 2009 Nobel Prize in Chemistry was awarded. The prize was based on X-ray crystallographic studies of the ribosome that helped to unravel the physical basis of its biological function as a molecular machine that translates mRNA into polypeptides. O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow
A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher educational institutions, a fellow can be a member of a highly ranked group of teachers at a particular college or university or a member of the governing body in some universities (such as the Fellows of Harvard College); it can also be a specially selected postgraduate student who has been appointed to a post (called a fellowship) granting a stipend, research facilities and other privileges for a fixed period (usually one year or more) in order to undertake some advanced study or research, often in return for teaching services. In the context of research and development-intensive large companies or corporations, the title "fellow" is sometimes given to a small number of senior scientists and engineers. In the context of medical education in No ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Arts
Bachelor of arts (BA or AB; from the Latin ', ', or ') is a bachelor's degree awarded for an undergraduate program in the arts, or, in some cases, other disciplines. A Bachelor of Arts degree course is generally completed in three or four years, depending on the country and institution. * Degree attainment typically takes four years in Afghanistan, Armenia, Azerbaijan, Bangladesh, Brazil, Brunei, China, Egypt, Ghana, Greece, Georgia, Hong Kong, Indonesia, Iran, Iraq, Ireland, Japan, Kazakhstan, Kenya, Kuwait, Latvia, Lebanon, Lithuania, Mexico, Malaysia, Mongolia, Myanmar, Nepal, Netherlands, Nigeria, Pakistan, the Philippines, Qatar, Russia, Saudi Arabia, Scotland, Serbia, South Korea, Spain, Sri Lanka, Taiwan, Thailand, Turkey, Ukraine, the United States and Zambia. * Degree attainment typically takes three years in Albania, Australia, Bosnia and Herzegovina, the Caribbean, Iceland, India, Israel, Italy, New Zealand, Norway, South Africa, Switzerland, the Canadian province of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Physics D
''Journal of Physics D: Applied Physics'' is a peer-reviewed scientific journal published by IOP Publishing, a subsidiary of the Institute of Physics in the United Kingdom. It was established in 1968 from the division of the earlier title, ''Proceedings of the Physical Society''. It has a broad coverage, including five main focus areas: magnetism; photonics and semiconductors; plasmas and plasma-surface interactions; applied surfaces and interfaces; structure and properties of matter and renewable energy/sustainability. The current editor-in-chief is Huiyun Liu (University College London). Abstracting and indexing ''Journal of Physics D'' is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Super-resolution Microscopy
Super-resolution microscopy is a series of techniques in optical microscopy that allow such images to have resolutions higher than those imposed by the diffraction limit, which is due to the diffraction of light. Super-resolution imaging techniques rely on the near-field (photon-tunneling microscopy as well as those that utilize the Pendry Superlens and near field scanning optical microscopy) or on the far-field. Among techniques that rely on the latter are those that improve the resolution only modestly (up to about a factor of two) beyond the diffraction-limit, such as confocal microscopy with closed pinhole or aided by computational methods such as deconvolution or detector-based pixel reassignment (e.g. re-scan microscopy, pixel reassignment), the 4Pi microscope, and structured-illumination microscopy technologies such as SIM and SMI. There are two major groups of methods for super-resolution microscopy in the far-field that can improve the resolution by a much larger fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical & Engineering News
''Chemical & Engineering News'' (''C&EN'') is a weekly news magazine published by the American Chemical Society, providing professional and technical news and analysis in the fields of chemistry and chemical engineering.C&EN Magazine Website Chemical and Engineering News, October 12, 2009, accessed October 12, 2009 It includes information on recent news and research in these fields, career and employment information, business and industry news, government and policy news, funding in these fields, and special reports. The magazine is available to all members of the American Chemical Society. History The magazine was established in 1923,C&EN- Happy Birthday to Us, accessed O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadcast news organisation and generates about 120 hours of radio and television output each day, as well as online news coverage. The service maintains 50 foreign news bureaus with more than 250 correspondents around the world. Deborah Turness has been the CEO of news and current affairs since September 2022. In 2019, it was reported in an Ofcom report that the BBC spent £136m on news during the period April 2018 to March 2019. BBC News' domestic, global and online news divisions are housed within the largest live newsroom in Europe, in Broadcasting House in central London. Parliamentary coverage is produced and broadcast from studios in London. Through BBC English Regions, the BBC also has regional centres across England and national news c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scanning Ion-conductance Microscopy
Scanning ion-conductance microscopy (SICM) is a scanning probe microscopy technique that uses an electrode as the probe tip. SICM allows for the determination of the surface topography of micrometer and even nanometer-range structures in aqueous media conducting electrolytes. The samples can be hard or soft, are generally non-conducting, and the non-destructive nature of the measurement allows for the observation of living tissues and cells, and biological samples in general. It is able to detect steep profile changes in samples and can be used to map a living cell's stiffness in tandem with its detailed topography, or to determine the mobility of cells during their migrations.Happel, P.; Wehner, F.; Dietzel, I.D. Scanning ion conductance microscopy–a tool to investigate electrolyte-nonconductor interfaces. In Modern Research and Educational Topics in Microscopy; FORMATEX: Badajoz, Spain, 2007; pp. 968–975. Working principle Scanning ion conductance microscopy is a technique ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Free Press (publisher)
Free Press was an American independent book publisher that later became an imprint of Simon & Schuster. It was one of the best-known publishers specializing in serious nonfiction, including path-breaking sociology books of the 1950s, 1960s and 1970s. After a period under new ownership in the 1980s of publishing neoconservative books, it was purchased by Simon & Schuster in 1994. By 2012, the imprint ceased to exist as a distinct entity; however, some books were still being published using the Free Press imprint. History Free Press was founded by Jeremiah Kaplan (1926–1993) and Charles Liebman in 1947 and concentrated on religion and social science. They chose the name Free Press because they wanted to print books devoted to civil liberties. It was launched with three classic titles: ''Division of Labor'' by Emile Durkheim, ''The Theory of Economic and Social Organization'' by Max Weber and ''The Scientific Outlook'' by Bertrand Russell. It was headquartered in Glencoe, Illino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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