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David Crews
David Pafford Crews is the Ashbel Smith Professor of Zoology and Psychology at the University of Texas at Austin. He has been a pioneer in several areas of reproductive biology, including evolution of sexual behavior and differentiation, neural and phenotypic plasticity, and the role of endocrine disruptors on brain and behavior. Biography Crews enrolled at the Munich campus of the University of Maryland in 1965, then transferred to the College Park campus in 1967. He graduated with a B.A. (Psychology and Sociology majors) in 1969. Following a summer as a research assistant at Walter Reed Army Institute of Research in the Department of Experimental Psychology he decided to pursue a degree in psychology. Crews received a Ph.D. in Psychobiology as a National Institute of Mental Health Predoctoral Trainee at the Institute of Animal Behavior at Rutgers University in 1973 under the mentorship of Daniel S. Lehrman and Jay S. Rosenblatt. He completed a National Science Foundation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jacksonville, Florida
Jacksonville is a city located on the Atlantic coast of northeast Florida, the most populous city proper in the state and is the largest city by area in the contiguous United States as of 2020. It is the seat of Duval County, with which the city government consolidated in 1968. Consolidation gave Jacksonville its great size and placed most of its metropolitan population within the city limits. As of 2020, Jacksonville's population is 949,611, making it the 12th most populous city in the U.S., the most populous city in the Southeast, and the most populous city in the South outside of the state of Texas. With a population of 1,733,937, the Jacksonville metropolitan area ranks as Florida's fourth-largest metropolitan region. Jacksonville straddles the St. Johns River in the First Coast region of northeastern Florida, about south of the Georgia state line ( to the urban core/downtown) and north of Miami. The Jacksonville Beaches communities are along the adjacent Atlantic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estrogen
Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3). Estradiol, an estrane, is the most potent and prevalent. Another estrogen called estetrol (E4) is produced only during pregnancy. Estrogens are synthesized in all vertebrates and some insects. Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history. Quantitatively, estrogens circulate at lower levels than androgens in both men and women. While estrogen levels are significantly lower in males than in females, estrogens nevertheless have important physiological roles in males. Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors (E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Andrea Gore
Andrea C. Gore is a neuroendocrinology professor at the University of Texas at Austin in the Division of Toxicology and Pharmacology, where she holds the Vacek Chair of Pharmacology. She is a prominent contributor to the field of reproductive endocrinology. Her research interests span from the neurological basis of reproductive aging to endocrine disruptors in the nervous system. From January 2013 through December 2017, she was Editor-in-Chief of the journal '' Endocrinology.'' She has also been elected into the Fellow to the American Association for the Advancement of Science. Education Gore graduated cum laude from Princeton University in 1985 with a A.B. in Biology. She received her Ph.D. in neuroscience from University of Wisconsin-Madison in 1990. For her Ph.D. she studied hormonal control of puberty onset in rhesus monkeys. From 1991 to 1995, she completed a postdoctoral fellowship in Molecular Medicine at Mount Sinai School of Medicine. Career After her postdoctoral f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Environmental Epigenetics
Environmental epigenetics is a branch of epigenetics that studies the influence of external environmental factors on the gene expression of a developing embryo. The way that genes are expressed may be passed down from parent to offspring through epigenetic modifications, although environmental influences do not alter the genome itself. During embryonic development, epigenetic modifications determine which genes are expressed, which in turn determines the embryo's phenotype. When the offspring is still developing, genes can be turned on and off depending on exposure to certain environmental factors. While certain genes being turned on or off can increase the risk of developmental diseases or abnormal phenotypes, there is also the possibility that the phenotype will be non-functional. Environmental influence on epigenetics is highly variable, but certain environmental factors can greatly increase the risk of detrimental diseases being expressed at both early and adult life stag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Discover Magazine
''Discover'' is an American general audience science magazine launched in October 1980 by Time Inc. It has been owned by Kalmbach Publishing since 2010. History Founding ''Discover'' was created primarily through the efforts of ''Time'' magazine editor Leon Jaroff. He noticed that magazine sales jumped every time the cover featured a science topic. Jaroff interpreted this as a considerable public interest in science, and in 1971, he began agitating for the creation of a science-oriented magazine. This was difficult, as a former colleague noted, because "Selling science to people who graduated to be managers was very difficult".Hevesi, Dennis"Leon Jaroff, Editor at Time and Discover Magazines, Dies at 85" ''The New York Times'', 21 October 2012 Jaroff's persistence finally paid off, and ''Discover'' magazine published its first edition in 1980. ''Discover'' was originally launched into a burgeoning market for science magazines aimed at educated non-professionals, intended to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrine Disruptor
Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause cancerous tumors, birth defects, and other developmental disorders. Found in many household and industrial products, endocrine disruptors "interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body that are responsible for development, behavior, fertility, and maintenance of homeostasis (normal cell metabolism)." Any system in the body controlled by hormones can be derailed by hormone disruptors. Specifically, endocrine disruptors may be associated with the development of learning disabilities, severe attention deficit disorder, cognitive and brain development problems. There has been controversy over endocrine disruptors, with some groups calling for swift action by regulators to re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vinclozolin
Vinclozolin (trade names Ronilan, Curalan, Vorlan, Touche) is a common dicarboximide fungicide used to control diseases, such as blights, rots and molds in vineyards, and on fruits and vegetables such as raspberries, lettuce, kiwi, snap beans, and onions. It is also used on turf on golf courses. Two common fungi that vinclozolin is used to protect crops against are '' Botrytis cinerea'' and '' Sclerotinia sclerotiorum''. First registered in 1981, vinclozolin is widely used but its overall application has declined. As a pesticide, vinclozolin is regulated by the United States Environmental Protection Agency (U.S. EPA). In addition to these restrictions within the United States, as of 2006 the use of this pesticide was banned in several countries, including Denmark, Finland, Norway, and Sweden. It has gone through a series of tests and regulations in order to evaluate the risks and hazards to the environment and animals. Among the research, a main finding is that vinclozolin has be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transgenerational Epigenetic Inheritance
Transgenerational epigenetic inheritance is the transmission of epigenetic markers from one organism to the next (i.e., from parent to child) that affects the traits of offspring without altering the nucleic acid primary structure, primary structure of DNA (i.e. the sequence of nucleotides) —in other words, epigenetics, epigenetically. The less precise term "epigenetic inheritance" may cover both cell–cell and organism–organism information transfer. Although these two levels of epigenetic inheritance are equivalent in unicellular organisms, they may have distinct mechanisms and evolutionary distinctions in multicellular organisms. Environmental factors can induce the epigenetic marks (epigenetic tags) for some epigenetically influenced traits, while some marks are heritable, thus leading some to consider that with epigenetics, modern biology no longer rejects the Lamarckism, inheritance of acquired characteristics (Lamarckism) as strongly as it once did. Epigenetic categories ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetically Modified Animal
Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing resistance to disease, etc. The vast majority of genetically modified animals are at the research stage while the number close to entering the market remains small. Production The process of genetically engineering mammals is a slow, tedious, and expensive process.Murray, Joo (20)Genetically modified animals Canada: Brainwaving As with other genetically modified organisms (GMOs), first genetic engineers must isolate the gene they wish to insert into the host organism. This can be taken from a cell containing the gene or artificially synthesised. If the chosen gene or the donor organism's genome has been well studied it may already be accessible from a genetic library. The gene is then combined with other genetic elements, including a promoter and terminator region and usually a selectable marker. A number of techniques ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leopard Gecko
The leopard gecko or common leopard gecko (''Eublepharis macularius'') is a ground-dwelling lizard native to the rocky dry grassland and desert regions of Afghanistan, Iran, Pakistan, India, and Nepal. The leopard gecko has become a popular pet, and due to extensive captive breeding it is sometimes referred to as the first domesticated species of lizard. Taxonomy Leopard geckos were first described as a species by zoologist Edward Blyth in 1854 as ''Eublepharis macularius''. The generic name ''Eublepharis'' is a combination of the Greek words ''eu'' (good) and ''blepharos'' (eyelid), as having eyelids is the primary characteristic that distinguishes members of this subfamily from other geckos, along with a lack of lamellae. The specific name ''macularius'' derives from the Latin word ''macula'' meaning "spot" or "blemish", referring to the animal's natural spotted markings. There are five subspecies of E. macularius: *''Eublepharis macularius afghanicus'' *''Eublepharis macula ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Temperature-dependent Sex Determination
Temperature-dependent sex determination (TSD) is a type of environmental sex determination in which the temperatures experienced during embryonic/larval development determine the sex of the offspring. It is only observed in reptiles and teleost fish. TSD differs from the chromosomal sex-determination systems common among vertebrates. It is the most studied type of environmental sex determination (ESD). Some other conditions, e.g. density, pH, and environmental background color, are also observed to alter sex ratio, which could be classified either as temperature-dependent sex determination or temperature-dependent sex differentiation, depending on the involved mechanisms. As sex-determining mechanisms, TSD and genetic sex determination (GSD) should be considered in an equivalent manner, which can lead to reconsidering the status of fish species that are claimed to have TSD when submitted to extreme temperatures instead of the temperature experienced during development in the wild, si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
