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David A. Karnofsky
David Aryah Karnofsky (March 28, 1914 – August 31, 1969) was an American clinical oncologist. In 1940, while he was a resident at the Colis P. Huntington Memorial Laboratory for Cancer Research of Harvard University, David A. Karnofsky began clinical research in cancer, and devoted himself to this area throughout his career. He was an internationally recognized specialist in cancer chemotherapy and affiliated with the Division of Experimental Chemotherapy, Sloan-Kettering Institute for Cancer Research. Education and Training David Karnofsky was the son of Lithuanian Jewish immigrants, Sam Karnofsky, a metals buyer, and Lena Karnofsky. David graduated from Belmont High School (Los Angeles, California) (1930), UCLA 1934. He received his masters (A.M, 1936) in biology from Stanford University with a thesis entitled ''Some effects of thyroidectomy on the mammary glands and some other organs in the rat.'' He received his medical degree (Alpha Omega Alpha 1940), also from Stanford U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karnofsky Score
In medicine (oncology and other fields), performance status is an attempt to quantify cancer patients' general well-being and activities of daily life. This measure is used to determine whether they can receive chemotherapy, whether dose adjustment is necessary, and as a measure for the required intensity of palliative care. It is also used in oncological randomized controlled trials as a measure of quality of life. Scoring systems There are various scoring systems. The most generally used are the Karnofsky score and the Zubrod score, the latter being used in publications by the WHO. For children, the Lansky score is used. Another common system is the Eastern Cooperative Oncology Group (ECOG) system. Parallel scoring systems include the ''Global Assessment of Functioning'' (GAF) score, which has been incorporated as the fifth ''axis'' of the ''Diagnostic and Statistical Manual'' (DSM) of psychiatry. Karnofsky scoring The Karnofsky Performance Score (KPS) ranking runs from 100 to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University School Of Medicine Alumni
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneurialism ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Oncologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1969 Deaths
This year is notable for Apollo 11's first landing on the moon. Events January * January 4 – The Government of Spain hands over Ifni to Morocco. * January 5 **Ariana Afghan Airlines Flight 701 crashes into a house on its approach to London's Gatwick Airport, killing 50 of the 62 people on board and two of the home's occupants. * January 14 – An explosion aboard the aircraft carrier USS ''Enterprise'' near Hawaii kills 27 and injures 314. * January 19 – End of the siege of the University of Tokyo, marking the beginning of the end for the 1968–69 Japanese university protests. * January 20 – Richard Nixon is sworn in as the 37th President of the United States. * January 22 – An assassination attempt is carried out on Soviet leader Leonid Brezhnev by deserter Viktor Ilyin. One person is killed, several are injured. Brezhnev escaped unharmed. * January 27 ** Fourteen men, 9 of them Jews, are executed in Baghdad for spying for Israel. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1914 Births
This year saw the beginning of what became known as World War I, after Archduke Franz Ferdinand of Austria, heir to the Austrian throne was assassinated by Serbian nationalist Gavrilo Princip. It also saw the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with the St. Petersburg–Tampa Airboat Line. Events January * January 1 – The St. Petersburg–Tampa Airboat Line in the United States starts services between St. Petersburg and Tampa, Florida, becoming the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with Tony Jannus (the first federally-licensed pilot) conveying passengers in a Benoist XIV flying boat. Abram C. Pheil, mayor of St. Petersburg, is the first airline passenger, and over 3,000 people witness the first departure. * January 11 – The Sakurajima volcano in Japan begins to erupt, becoming effusive after a very large earthquake ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Home Of Peace Cemetery (East Los Angeles)
The Home of Peace Cemetery ( ''Beit Kvarot Beit Shalom'') is a Jewish cemetery in Los Angeles, California. Location It is located at 4334 Whittier Boulevard west of Interstate 710 in East Los Angeles, California. It is across from Calvary Catholic Cemetery and next to Beth Israel Cemetery and Mount Zion Cemetery. History In 1853, the first and oldest Jewish cemetery in Los Angeles was established in Chavez Ravine, near the present-day Dodger Stadium. In 1901, Kaspare Cohn donated 30 acres (12.1 ha) of land for the establishment of this cemetery. The bodies interred at Chavez Ravine were moved to East Los Angeles's Home of Peace Memorial Park between 1902 and 1910. There are a number of famous rabbis buried here, and amongst others a few celebrities from the entertainment industry as well. Notable interments * Raymond Moscatel (1931–2022), Seattle University Basketball player beat The Harlem Globe Trotters in 1952 * Inez Asher (1911–2006), television writer and n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obituary
An obituary ( obit for short) is an article about a recently deceased person. Newspapers often publish obituaries as news articles. Although obituaries tend to focus on positive aspects of the subject's life, this is not always the case. According to Nigel Farndale, the Obituaries Editor of ''The Times'': "Obits should be life affirming rather than gloomy, but they should also be opinionated, leaving the reader with a strong sense of whether the subject lived a good life or bad; whether they were right or wrong in the handling of their public affairs." In local newspapers, an obituary may be published for any local resident upon death. A necrology is a register or list of records of the deaths of people related to a particular organization, group or field, which may only contain the sparsest details, or small obituaries. Historical necrologies can be important sources of information. Two types of paid advertisements are related to obituaries. One, known as a death notice, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the ''Journal of Clinical Oncology The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by the Lippincott Williams ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung Cancer
Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from transformed, malignant cells that originate as epithelial cells, or from tissues composed of epithelial cells. Other lung cancers, such as the rare sarcomas of the lung, are generated by the malignant transformation of connective tissues (i.e. nerve, fat, muscle, bone), which arise from mesenchymal cells. Lymphomas and melanomas (from lymphoid and melanocyte cell lineages) can also rarely result in lung cancer. In time, this uncontrolled neoplasm, growth can metastasis, metastasize (spreading beyond the lung) either by direct extension, by entering the lymphatic circulation, or via hematogenous, bloodborne spread – into nearby tissue or other, more distant parts of the body. Most cancers that originate from within the lungs, known as primary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph H
Joseph is a common male given name, derived from the Hebrew Yosef (יוֹסֵף). "Joseph" is used, along with "Josef", mostly in English, French and partially German languages. This spelling is also found as a variant in the languages of the modern-day Nordic countries. In Portuguese and Spanish, the name is "José". In Arabic, including in the Quran, the name is spelled '' Yūsuf''. In Persian, the name is "Yousef". The name has enjoyed significant popularity in its many forms in numerous countries, and ''Joseph'' was one of the two names, along with ''Robert'', to have remained in the top 10 boys' names list in the US from 1925 to 1972. It is especially common in contemporary Israel, as either "Yossi" or "Yossef", and in Italy, where the name "Giuseppe" was the most common male name in the 20th century. In the first century CE, Joseph was the second most popular male name for Palestine Jews. In the Book of Genesis Joseph is Jacob's eleventh son and Rachel's first son, and k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Corps
The Chemical Corps is the branch of the United States Army tasked with defending against chemical, biological, radiological, and nuclear (CBRN) weapons. The Chemical Warfare Service was established on 28 June 1918, combining activities that until then had been dispersed among five separate agencies of the United States federal government. It was made a permanent branch of the Regular Army by the National Defense Act of 1920. In 1945, it was redesignated the Chemical Corps. History Origins Discussion of the topic dates back to the American Civil War. A letter to the War Department dated 5 April 1862 from New York City resident John Doughty proposed the use of chlorine shells to drive the Confederate Army from its positions. Doughty included a detailed drawing of the shell with his letter. It is unknown how the military reacted to Doughty's proposal but the letter was unnoticed in a pile of old official documents until modern times. Another American, Forrest Shepherd, also propos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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