|
David A. Evans
David A. Evans (January 11, 1941 – April 29, 2022) was an American chemist who was the Abbott and James Lawrence professor of chemistry at Harvard University. He was a prominent figure in the field of organic chemistry and his research focused on synthetic chemistry and total synthesis, particularly of large biologically active molecules. Among his best-known work is the development of aldol reaction methodology (for example, Evans' acyl oxazolidinone method). Early life and education Evans was born on January 11, 1941, in Washington, D.C. He received his A.B. from Oberlin College in 1963, where he worked with Norman Craig. He began his graduate work at the University of Michigan with Robert E. Ireland, but moved with the Ireland group to the California Institute of Technology and received his Ph.D. from Caltech in 1967. Academic career Evans began his independent research career at the University of California, Los Angeles, where he joined the faculty in 1967 and became ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kevin Campos
Kevin () is the anglicized form of the Irish masculine given name (; mga, Caoimhghín ; sga, Cóemgein ; Latinized as ). It is composed of "dear; noble"; Old Irish and ("birth"; Old Irish ). The variant ''Kevan'' is anglicized from , an Irish diminutive form.''A Dictionary of First Names''. Oxford University Press (2007) s.v. "Kevin". The feminine version of the name is (anglicised as ''Keeva'' or ''Kweeva''). History Saint Kevin (d. 618) founded Glendalough abbey in the Kingdom of Leinster in 6th-century Ireland. Canonized in 1903, he is one of the patron saints of the Archdiocese of Dublin. Caomhán of Inisheer, the patron saint of Inisheer, Aran Islands, is properly anglicized ''Cavan'' or ''Kevan'', but often also referred to as "Kevin". The name was rarely given before the 20th century. In Ireland an early bearer of the anglicised name was Kevin Izod O'Doherty (1823–1905) a Young Irelander and politician; it gained popularity from the Gaelic revival of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anionic
An ion () is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by convention. The net charge of an ion is not zero because its total number of electrons is unequal to its total number of protons. A cation is a positively charged ion with fewer electrons than protons while an anion is a negatively charged ion with more electrons than protons. Opposite electric charges are pulled towards one another by electrostatic force, so cations and anions attract each other and readily form ionic compounds. Ions consisting of only a single atom are termed atomic or monatomic ions, while two or more atoms form molecular ions or polyatomic ions. In the case of physical ionization in a fluid (gas or liquid), "ion pairs" are created by spontaneous molecule collisions, where each generated pair consists of a free electron and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Professor Emeritus
''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title the rank of the last office held". In some cases, the term is conferred automatically upon all persons who retire at a given rank, but in others, it remains a mark of distinguished service awarded selectively on retirement. It is also used when a person of distinction in a profession retires or hands over the position, enabling their former rank to be retained in their title, e.g., "professor emeritus". The term ''emeritus'' does not necessarily signify that a person has relinquished all the duties of their former position, and they may continue to exercise some of them. In the description of deceased professors emeritus listed at U.S. universities, the title ''emeritus'' is replaced by indicating the years of their appointmentsThe Protoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Professor
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital letter nearly always refers to a full professo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aldol Reaction
The aldol reaction is a means of forming carbon–carbon bonds in organic chemistry. Discovered independently by the Russian chemist Alexander Borodin in 1869 and by the French chemist Charles-Adolphe Wurtz in 1872, the reaction combines two carbonyl compounds (the original experiments used aldehydes) to form a new β-hydroxy carbonyl compound. These products are known as ''aldols'', from the ''ald''ehyde + alcoh''ol'', a structural motif seen in many of the products. Aldol structural units are found in many important molecules, whether naturally occurring or synthetic. For example, the aldol reaction has been used in the large-scale production of the commodity chemical pentaerythritol and the synthesis of the heart disease drug Lipitor (atorvastatin, calcium salt). The aldol reaction unites two relatively simple molecules into a more complex one. Increased complexity arises because up to two new stereogenic centers (on the Alpha carbon, α- and β-carbon of the aldol adduct, mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aldol Reaction
The aldol reaction is a means of forming carbon–carbon bonds in organic chemistry. Discovered independently by the Russian chemist Alexander Borodin in 1869 and by the French chemist Charles-Adolphe Wurtz in 1872, the reaction combines two carbonyl compounds (the original experiments used aldehydes) to form a new β-hydroxy carbonyl compound. These products are known as ''aldols'', from the ''ald''ehyde + alcoh''ol'', a structural motif seen in many of the products. Aldol structural units are found in many important molecules, whether naturally occurring or synthetic. For example, the aldol reaction has been used in the large-scale production of the commodity chemical pentaerythritol and the synthesis of the heart disease drug Lipitor (atorvastatin, calcium salt). The aldol reaction unites two relatively simple molecules into a more complex one. Increased complexity arises because up to two new stereogenic centers (on the Alpha carbon, α- and β-carbon of the aldol adduct, mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Total Synthesis
Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest. Total synthesis targets can also be organometallic or inorganic, though these are rarely encountered. Total synthesis projects often require a wide diversity of reactions and reagents, and subsequently requires broad chemical knowledge and training to be successful. Often, the aim is to discover a new route of synthesis for a target molecule for which there already exist known routes. Sometimes, however, no ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synthetic Chemistry
As a topic of chemistry, chemical synthesis (or combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as '' reagents'' or ''reactants'') that will experience a transformation when subjected to certain conditions. Various reaction types can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of processing (" work-up") or purification procedure to isolate the final product. The amount produced by chemical synthesis is known as the ''reaction yield''. Typically, yields are expressed as a mass in grams (in a laboratory setting) or as a percentage of the total theoretical quantity th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes physical and chemical properties, and evaluation of chemical reactivity to understand their behavior. The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical ( in silico) study. The range of chemicals studied in organic chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (included in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marisa Kozlowski
Marisa C. Kozlowski (born 1967) is an American chemist who is Professor of Organic and Catalysis Chemistry at the University of Pennsylvania. Her research considers asymmetric synthesis and the development of cost effective catalysts. She was elected Fellow of the American Association for the Advancement of Science in 2012 and American Chemical Society in 2013. Early life and education Kozlowski was born in Hamburg, and raised in Liverpool, New York. She studied chemistry at Cornell University. She moved to California for her graduate studies, where she joined the laboratory of Paul Bartlett at the University of California, Berkeley. As an undergraduate, she only knew of one woman member of faculty, and as a postgraduate only two. Her research considered the design of enzyme inhibitors. She moved to Harvard University as a postdoctoral research fellow, where she worked with David A. Evans on organic synthesis. Research and career In 1997, Kozlowski joined the faculty at the U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tomislav Rovis
Tomislav (, ) is a masculine given name of Slavic origin, that is widespread amongst the South Slavs. The meaning of the name ''Tomislav'' is thought to have derived from the Old Slavonic verb "'' tomiti''" or "'' tomit'''" meaning to "''languish''", "''torture''" or "''struggle''", combined with "''slava"'' meaning glory. Other origin theories suggest the name is a variant derived from the New Testament Apostle Thomas, whilst another theory postulates that it is a Slavicised corruption of the (Dog) Latin "''Dominus Slavus''". The first recorded bearer of the name was the 10th-century King Tomislav of Croatia, for this reason it has become popular amongst Croats. In Croatia, the name Tomislav was among the top ten most common masculine given name in the decades between 1970 and 1999. The name is also widespread amongst Serbs, reaching popularity during the 1930s and 40s. King Alexander I of Yugoslavia gave his second child the name as a symbolic gesture of unity for his subject ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
