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Danshen
''Salvia miltiorrhiza'' (), also known as red sage, Chinese sage, tan shen, or danshen, is a perennial plant in the genus ''Salvia'', highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at elevation, preferring grassy places in forests, hillsides, and along stream banks. The specific epithet ''miltiorrhiza'' means "red ochre root". Chemical constituents Chemical compounds isolated from ''Salvia miltiorrhiza'' include salvianolic acid (or salvianolic acid B), dihydrotanshinone, miltirone, tanshinone I, and tanshinone IIA. Tanshinone IIA is one of the most abundant constituents of the root of ''Salvia miltiorrhiza''. Description ''S. miltiorrhiza'' is a deciduous perennial with branching stems that are tall, with widely spaced leaves that are both simple and divided. The inflorescences are covered with hairs and sticky glands. Flowers grow in whorls, with light purple to lavender blue corollas that are approximately long, with a ...
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Salvianolic Acid
''Salvia miltiorrhiza'' (), also known as red sage, Chinese sage, tan shen, or danshen, is a perennial plant in the genus ''Salvia'', highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at elevation, preferring grassy places in forests, hillsides, and along stream banks. The specific epithet ''miltiorrhiza'' means "red ochre root". Chemical constituents Chemical compounds isolated from ''Salvia miltiorrhiza'' include salvianolic acid (or salvianolic acid B), dihydrotanshinone, miltirone, tanshinone I, and tanshinone IIA. Tanshinone IIA is one of the most abundant constituents of the root of ''Salvia miltiorrhiza''. Description ''S. miltiorrhiza'' is a deciduous perennial with branching stems that are tall, with widely spaced leaves that are both simple and divided. The inflorescences are covered with hairs and sticky glands. Flowers grow in whorls, with light purple to lavender blue corollas that are approximately long, with a ...
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Anticoagulation
Anticoagulants, commonly known as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time. Some of them occur naturally in blood-eating animals such as leeches and mosquitoes, where they help keep the bite area unclotted long enough for the animal to obtain some blood. As a class of medications, anticoagulants are used in therapy for thrombotic disorders. Oral anticoagulants (OACs) are taken by many people in pill or tablet form, and various intravenous anticoagulant dosage forms are used in hospitals. Some anticoagulants are used in medical equipment, such as sample tubes, blood transfusion bags, heart–lung machines, and dialysis equipment. One of the first anticoagulants, warfarin, was initially approved as a rodenticide. Anticoagulants are closely related to antiplatelet drugs and thrombolytic drugs by manipulating the various pathways of blood coagulation. Specifically, antiplatelet drugs inhibit platelet aggre ...
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Alexander Bunge
Alexander Georg von Bunge (russian: Алекса́ндр Андре́евич Бу́нге; – ) was a Russian botanist. He is best remembered for scientific expeditions into Asia and especially Siberia. Early life and education Bunge was born under the name, Alexander Andreevič von Bunge on in Kyiv as second son of a family that belonged to the German minority in Tsarist Russia. HIs father, Andreas Theodor was a pharmacist who had emigrated from East Prussia to Russia with his grandfather in the 18th century and his mother, Elisabeth von Bunge, . They moved to Dorpat in 1815 after his father's death in 1814 and attended highschool from 1818 to 1821. He was educated at Dorpat and where he passed through the gymnasium during the period of 1821–1825. Then, he studied medicine and obtained his Doctorate of Medicine from University of Tartu on 1825. He also studied botany there under Carl Friedrich von Ledebour and completed his thesis entitled ''De relatione methodi plan ...
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Dizziness
Dizziness is an imprecise term that can refer to a sense of disorientation in space, vertigo, or lightheadedness. It can also refer to disequilibrium or a non-specific feeling, such as giddiness or foolishness. Dizziness is a common medical complaint, affecting 20-30% of persons. Dizziness is broken down into 4 main subtypes: vertigo (~25-50%), disequilibrium (less than ~15%), presyncope (less than ~15%), and nonspecific dizziness (~10%). * Vertigo is the sensation of spinning or having one's surroundings spin about them. Many people find vertigo very disturbing and often report associated nausea and vomiting. * Presyncope describes lightheadedness or feeling faint; the name relates to syncope, which is actually fainting. * Disequilibrium is the sensation of being off balance and is most often characterized by frequent falls in a specific direction. This condition is not often associated with nausea or vomiting. * Non-specific dizziness may be psychiatric in origin. It is ...
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Flora Of China
The flora of China consists of a diverse range of plant species including over 39,000 vascular plants, 27,000 species of fungi and 3000 species of bryophytes.Wu, Z. Y., P. H. Raven & D. Y. Hong, eds. 2006. Flora of China. Vol. 22 (Poaceae). Science Press, Beijing, and Missouri Botanical Garden Press, St. Louis More than 30,000 plant species are native to China, representing nearly one-eighth of the world's total plant species, including thousands found nowhere else on Earth. China's land, extending over 9.6 million km, contains a variety of ecosystems and climates for plants to grow in. Some of the main climates include shores, tropical and subtropical forests, deserts, elevated plateaus and mountains. The events of the continental drift and early Paleozoic Caledonian movement also play a part in creating climatic and geographical diversity resulting in high levels of endemic vascular flora. These landscapes provide different ecosystems and climates for plants to grow in, creati ...
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Plants Used In Traditional Chinese Medicine
Plants are predominantly photosynthetic eukaryotes of the kingdom Plantae. Historically, the plant kingdom encompassed all living things that were not animals, and included algae and fungi; however, all current definitions of Plantae exclude the fungi and some algae, as well as the prokaryotes (the archaea and bacteria). By one definition, plants form the clade Viridiplantae (Latin name for "green plants") which is sister of the Glaucophyta, and consists of the green algae and Embryophyta (land plants). The latter includes the flowering plants, conifers and other gymnosperms, ferns and their allies, hornworts, liverworts, and mosses. Most plants are multicellular organisms. Green plants obtain most of their energy from sunlight via photosynthesis by primary chloroplasts that are derived from endosymbiosis with cyanobacteria. Their chloroplasts contain chlorophylls a and b, which gives them their green color. Some plants are parasitic or mycotrophic and have lost the ability ...
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Angina
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by ischemia, insufficient blood flow to the Cardiac muscle, heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typically the result of vascular occlusion, obstruction or vasospasm, spasm of the coronary arteries, arteries that supply blood to the heart muscle. The main mechanism of coronary artery obstruction is atherosclerosis as part of coronary artery disease. Other causes of angina include cardiac arrhythmia, abnormal heart rhythms, heart failure and, less commonly, anemia. The term derives from the Latin ''angere'' ("to strangle") and ''pectus'' ("chest"), and can therefore be translated as "a strangling feeling in the chest". There is a weak relationship between severity of angina and degree of oxygen deprivation in the heart muscle, however, the severity of angina does not always match the degree of oxygen deprivation to the heart or the risk of a ...
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Heart Attack
A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to the coronary artery of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw. Often it occurs in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat or feeling tired. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of e ...
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Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ...
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Stroke
A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of a stroke may include an inability to move or feel on one side of the body, problems understanding or speaking, dizziness, or loss of vision to one side. Signs and symptoms often appear soon after the stroke has occurred. If symptoms last less than one or two hours, the stroke is a transient ischemic attack (TIA), also called a mini-stroke. A hemorrhagic stroke may also be associated with a severe headache. The symptoms of a stroke can be permanent. Long-term complications may include pneumonia and loss of bladder control. The main risk factor for stroke is high blood pressure. Other risk factors include high blood cholesterol, tobacco smoking, obesity, diabetes mellitus, a previous TIA, end-st ...
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Cochrane Review
Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world. The group conducts systematic reviews of health-care interventions and diagnostic tests and publishes them in the Cochrane Library. According to the Library, articles are available via one-click access, but some require paid subscription or registration before reading. A few reviews, in occupational health for example, incorporate results from non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. History Cochrane, previously known as the Cochrane Collaboration, was founded in 1 ...
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Cerebrovascular Diseases
Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. Arteries supplying oxygen and nutrients to the brain are often damaged or deformed in these disorders. The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and sometimes a hemorrhagic stroke. Hypertension (high blood pressure) is the most important contributing risk factor for stroke and cerebrovascular diseases as it can change the structure of blood vessels and result in atherosclerosis. Atherosclerosis narrows blood vessels in the brain, resulting in decreased cerebral perfusion. Other risk factors that contribute to stroke include smoking and diabetes. Narrowed cerebral arteries can lead to ischemic stroke, but continually elevated blood pressure can also cause tearing of vessels, leading to a hemorrhagic stroke. A stroke usually presents with an abrupt onset of a neurologic deficit – such as h ...
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