Daniel P. Kelly
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Daniel P. Kelly
Daniel P. Kelly (born 1955) is Director of the Penn 2] and CHOP 4] Cardiovascular Institutes (CVI) and the Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases at the University of Pennsylvania Perelman School of Medicine and the Rachel Ash Presidential Professor at Children’s Hospital of Philadelphia (CHOP). He is a cardiologist and physician-scientist recognized for his contributions to the transcriptional control of mitochondrial function and the metabolic origins of heart disease. Education and Career Kelly obtained his medical degree from the University of Illinois College of Medicine, internal medicine residency training at Barnes Hospital in St. Louis, and clinical cardiology and research training at Washington University School of Medicine (WUSM) in St. Louis. He joined the WUSM faculty in 1989 and rapidly moved up the ranks to Professor of Medicine, Molecular Biology & Pharmacology, and Pediatrics, Chief of the Cardiovascular Division /sup>, Alumni ...
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Estrogen-related Receptor
The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones. There are three human estrogen related receptors: * ERRα () * ERRβ () * ERRγ () ERRs bind enhancers throughout the genome where they exert effects on gene regulation. The ERR family exhibit varying transcriptional activation capabilities and physically interact with the transcriptional co-activators PGC1-alpha and PGC1-beta, via their AF-2 domains and the leucine-rich nuclear receptor interacting motifs (LxxLL) present in the PGC-1 proteins, The ERR family have been demonstrated to control energy homeostasis, oxidative metabolism, and mitochondrial biogenesis, while effecting mammalian physiology in the heart, brown adipose tissue, white adipose tissue, placenta, macrophages, and demonstrated additional roles ...
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University Of Pennsylvania Faculty
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ...
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21st-century American Physicians
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman emperor, a ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Journal Of The American College Of Cardiology
The ''Journal of the American College of Cardiology'' is a peer-reviewed medical journal covering all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the-art papers, review articles, and editorials interpreting and commenting on the research presented, published by the American College of Cardiology. Abstracting and indexing The journal is abstracted and indexed in Current Contents, EMBASE, MEDLINE, Science Citation Index, and Scopus. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 24.094, ranking it 4th out of 141 journals in the category "Cardiac & Cardiovascular Systems". Associated journals * ''JACC: Basic to Translational Science'' * ''JACC: CardioOncology'' * '' JACC: Cardiovascular Imaging'' * '' JACC: Cardiovascular Interventions'' * ''JACC: Case Reports'' * ''JACC: Clinical Electrophysiology'' * ''JACC: Heart Failure'' See also * ''America ...
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Journal Of Clinical Investigation
The ''Journal of Clinical Investigation'' is a twice-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation. Articles focus on the mechanisms of disease, with an emphasis on basic research, early-stage clinical studies in humans, and new research tools and techniques. The journal also publishes reviews in edited series or as stand-alone articles, commentaries on research, editorials, and feature items. The editor-in-chief is Elizabeth M. McNally (Northwestern University). Abstracting and indexing The journal is abstracted and indexed in: Editors-in-chief The following persons have been editor-in-chief of the journal: Most cited articles The following articles have received the most citations , according to Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) fr ...
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Circulation Research
''Circulation Research'' is a biweekly peer-reviewed medical journal published by Lippincott Williams & Wilkins. It is the official journal of the American Heart Association and its Council on Basic Cardiovascular Sciences. The journal covers research on all aspects of the cardiovascular system. History The journal was established in 1953 by Carl J. Wiggers. The following people have been editor-in-chief: Abstracting and indexing This journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2018 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 15.862. References External links * Cardiology journals English-language journals Publications established in 1953 Lippincott Williams & Wilkins academic journal ...
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Circulation (journal)
''Circulation'' is a scientific journal published by Lippincott Williams & Wilkins for the American Heart Association. The journal publishes articles related to research in and the practice of cardiovascular diseases, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in applied (translational) and basic research. Its 2020 impact factor is 29.690, ranking it third among journals in the Cardiac and Cardiovascular Systems category and first in the Peripheral Vascular Disease category.2020 Journal Citation Reports (Clarivate Analytics, 2021) Articles become open access after a 12-month embargo period. 2008 saw the appearance of six subspecialty journals. The first edition of ''Circulation: Arrhythmia and Electrophysiology'' appeared in April 2008, followed by an edition dedicated to heart failure in May titled ''Circulation: Heart Failure''. The remaining four journals launched once per month from July through October ...
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Genes & Development
''Genes & Development'' is a peer-reviewed scientific journal covering molecular biology, molecular genetics, cell biology, and development. It was established in 1987 and is published twice monthly by Cold Spring Harbor Laboratory Press in association with The Genetics Society. According to the ''Journal Citation Reports'', the journal has a 2012 impact factor of 12.44, ranking it 14th out of 181 journals in the category "Cell Biology", third out of 40 journals in the category "Developmental Biology", and 7th out of 158 journals in the category "Genetics & Heredity". Over 1999–2004, the journal was ranked fifth in the "Molecular Biology and Genetics" category according to ''ScienceWatch'', with an average of 47 citations per paper. All issues are available online via the journal website as PDFs, with a text version additionally available from August 1997. Content over 6 months old is freely available. Since 1989, the editor-in-chief has been Terri Grodzicker (Cold Spring Harbor ...
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Association Of American Physicians
The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine." Election to the AAP is an honor extended to individuals with outstanding credentials in biomedical science and/or translational biomedical research and is limited to 60 persons per year. The AAP includes about 1000 active members and 550 emeritus and honorary members. The great majority are US citizens. However, other countries are also represented. The overarching goals of the AAP include the promotion of professional and social interaction among biomedical scientists, the dissemination of important information related to biomedical science and teaching, the recognition of outstanding scientists through membership, and the establishment of role models to kindle new generations of high achievers in medicine and medical science. The rang ...
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American Society For Clinical Investigation
The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 physician-scientists from all medical specialties belong. Prospective members are proposed by standing members of the society and elected to ASCI on the basis of an outstanding record of scholarly achievement in biomedical research. The ASCI includes physician-scientists who are active clinically, in basic research, or in teaching. Many of its senior members are widely recognized leaders in academic medicine. As of 2015 the membership of ASCI has included 417 members of the National Academy of Medicine, 191 members of the National Academy of Sciences, Engineering, and Medicine, 40 Lasker Award winners, and 19 Nobel laureates. The ASCI supports the research into basic mechanisms and/or treatment of human diseases, and to the education of fut ...
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