DHQ Synthase
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DHQ Synthase
DHQ may refer to: * 3-Dehydroquinic acid, the first carbocyclic intermediate of the shikimate pathway * Digital Humanities Quarterly ''Digital Humanities Quarterly'' is a peer-reviewed open-access academic journal covering all aspects of digital media in the humanities. The journal is also a community experiment in journal publication. The journal is funded and published by the ..., a peer-reviewed open-access academic journal covering all aspects of digital media in the humanities * DHQ, the station code for Dharakhoh railway station, Madhya Pradesh, India {{Disambiguation ...
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3-Dehydroquinic Acid
3-Dehydroquinic acid (DHQ) is the first carbocyclic intermediate of the shikimate pathway. It is created from 3-deoxyarabinoheptulosonate 7-phosphate, a 7-carbon ulonic acid, by the enzyme DHQ synthase. The mechanism of ring closure is complex, but involves an aldol condensation at C-2 and C-7. It has the same structure as quinic acid, which is found in coffee, but the C-3 hydroxyl is oxidized to a ketone group. 3-Dehydroquinic acid undergoes five further enzymatic steps in the remainder of the shikimate pathway to chorismic acid, a precursor to tyrosine, 3-phenylalanine, tryptophan, and some vitamins, including: * Vitamin K * Pteroylmonoglutamic acid, called folate. 3-Dehydroquinate can also be a precursor to pyrroloquinoline quinone (PQQ), an alternate redox coenzyme involved in oxidative phosphorylation. Biosynthesis 3-Dehydroquinate goes through beta oxidation, similar to fatty acids. Then, this compound (6-oxo-3-dehydro-quinate) is transaminated to 6-amino-3-dehydroquin ...
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Digital Humanities Quarterly
''Digital Humanities Quarterly'' is a peer-reviewed open-access academic journal covering all aspects of digital media in the humanities. The journal is also a community experiment in journal publication. The journal is funded and published by the Alliance of Digital Humanities Organizations and its editor-in-chief is Julia Flanders. Editorial policy ''Digital Humanities Quarterly'' has been noted among the "few interesting attempts to peer review born-digital scholarship." Having emerged from a desire to disseminate digital humanities practices to the wider arts and humanities community and beyond, the journal is committed to open access and open standards to deliver journal content, publishing under a Creative Commons Creative Commons (CC) is an American non-profit organization and international network devoted to educational access and expanding the range of creative works available for others to build upon legally and to share. The organization has release ... license. I ...
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