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Ductal Lavage
Ductal lavage is a screening method used in at-risk women for breast cancer detection. In this method, cells are collected from milk ducts in the breast. The procedure involves inserting a catheter (tube) into the nipple, which releases a small amount of salt water into the duct. The water picks up breast cells and the entire fluid is then retrieved and sent to be examined for cells, which are checked under a microscope. Apart from clinical breast examination and mammography, ductal lavage can also be used to detect breast cancer. Procedure Ductal lavage is a non-invasive screening procedure. It is used to detect precancerous and cancerous cells in the breast ducts. It is a safe and well-tolerated procedure. Some doctors might apply anesthetic cream to numb the nipple area. In ductal lavage, the doctor applies suction to the nipple in order to bring out fluid from the milk ducts that eventually end at the nipple. A micro-catheter is inserted into the milk duct and the fluid is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breast Examination
Breast examination, also known as clinical breast examination, is a physical examination performed by a medical professional on an individual presenting with signs and symptoms in a breast, periodically on some people with a family history of breast disease, or on a person with an incidental abnormal finding on imaging such as mammography. Techniques may vary from one medical professional to another, but essentially follow the principles of obtaining informed consent, inspecting and then palpating the breasts, followed by looking for nearby lymph nodes. A chaperone is offered prior to beginning the examination. The method is similar in both males and females. Examination findings are generally reported using particular terms; size, symmetry, texture, description of any lump and appearance of skin. Some organisations recommend a breast examination as part of routine screening, typically in some high risk groups. See also *Breast self-examination Breast self-examination (BSE ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Northwestern Memorial Hospital
Northwestern Memorial Hospital (NMH) is a nationally ranked academic medical center located on Northwestern University’s Chicago campus in Streeterville, Chicago, Illinois. It is the flagship campus for Northwestern Medicine and the primary teaching hospital for the Feinberg School of Medicine at Northwestern University. Affiliated institutions also located on campus include the Ann & Robert H. Lurie Children's Hospital with Level I pediatric trauma care and the Shirley Ryan AbilityLab, a leader in physical medicine and rehabilitation. In 2022, '' U.S. News & World Report'' ranked Northwestern Memorial as the top hospital in both Chicago and Illinois for the eleventh consecutive year and #9 in the nation. In the same report, Northwestern Memorial is nationally ranked in 11 adult specialties including #5 in Neurology & Neurosurgery. History Origins Northwestern Memorial Hospital's roots date back to 1865 when the then Deaconess Hospital of Chicago was established by lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Risk Assessment
Broadly speaking, a risk assessment is the combined effort of: # identifying and analyzing potential (future) events that may negatively impact individuals, assets, and/or the environment (i.e. hazard analysis); and # making judgments "on the tolerability of the risk on the basis of a risk analysis" while considering influencing factors (i.e. risk evaluation). Put in simpler terms, a risk assessment determines possible mishaps, their likelihood and consequences, and the tolerances for such events. The results of this process may be expressed in a quantitative or qualitative fashion. Risk assessment is an inherent part of a broader risk management strategy to help reduce any potential risk-related consequences. Need Individual risk assessment Risk assessment are done in individual cases, including patient and physician interactions. Individual judgements or assessments of risk may be affected by psychological, ideological, religious or otherwise subjective factors, which impa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pap Test
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), cervical smear (BE), cervical screening (BE), or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or colon (in both men and women). Abnormal findings are often followed up by more sensitive diagnostic procedures and, if warranted, interventions that aim to prevent progression to cervical cancer. The test was independently invented in the 1920s by Georgios Papanikolaou and Aurel Babeș and named after Papanikolaou. A simplified version of the test was introduced by Anna Marion Hilliard in 1957. A Pap smear is performed by opening the vagina with a speculum and collecting cells at the outer opening of the cervix at the transformation zone (where the outer squamous cervical cells meet the inner glandular endocervical cells), using an Ayre spatula or a cytobrush. A similar method is used to co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Suction
Suction is the colloquial term to describe the air pressure differential between areas. Removing air from a space results in a pressure differential. Suction pressure is therefore limited by external air pressure. Even a perfect vacuum cannot suck with more pressure than is available in the surrounding environment. Suctions can form on the sea, for example, when a ship founders. When the pressure in one part of a physical system is reduced relative to another, the fluid in the higher pressure region will exert a force relative to the region of lowered pressure, referred to as pressure-gradient force. Pressure reduction may be static, as in a piston and cylinder arrangement, or dynamic, as in the case of a vacuum cleaner when air flow results in a reduced pressure region. When animals breathe, the diaphragm and muscles around the rib cage cause a change of volume in the lungs. The increased volume of the chest cavity decreases the pressure inside, creating an imbalance with t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-invasive Procedure
A medical procedure is defined as ''non-invasive'' when no break in the skin is created and there is no contact with the mucosa, or skin break, or internal body cavity beyond a natural or artificial body orifice. For example, deep palpation and percussion are non-invasive but a rectal examination is invasive. Likewise, examination of the ear-drum or inside the nose or a wound dressing change all fall outside the definition of ''non-invasive procedure''. There are many non-invasive procedures, ranging from simple observation, to specialised forms of surgery, such as radiosurgery. Extracorporeal shock wave lithotripsy is a non-invasive treatment of stones in the kidney, gallbladder or liver, using an acoustic pulse. For centuries, physicians have employed many simple non-invasive methods based on physical parameters in order to assess body function in health and disease (physical examination and inspection), such as pulse-taking, the auscultation of heart sounds and lung sounds ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mammography
Mammography (also called mastography) is the process of using low-energy X-rays (usually around 30 kVp) to examine the human breast for diagnosis and screening. The goal of mammography is the early detection of breast cancer, typically through detection of characteristic masses or microcalcifications. As with all X-rays, mammograms use doses of ionizing radiation to create images. These images are then analyzed for abnormal findings. It is usual to employ lower-energy X-rays, typically Mo (K-shell X-ray energies of 17.5 and 19.6 keV) and Rh (20.2 and 22.7 keV) than those used for radiography of bones. Mammography may be 2D or 3D (tomosynthesis), depending on the available equipment and/or purpose of the examination. Ultrasound, ductography, positron emission mammography (PEM), and magnetic resonance imaging (MRI) are adjuncts to mammography. Ultrasound is typically used for further evaluation of masses found on mammography or palpable masses that may or may not be seen on mammogr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physical Examination
In a physical examination, medical examination, or clinical examination, a medical practitioner examines a patient for any possible medical signs or symptoms of a medical condition. It generally consists of a series of questions about the patient's medical history followed by an examination based on the reported symptoms. Together, the medical history and the physical examination help to determine a diagnosis and devise the treatment plan. These data then become part of the medical record. Types Routine The ''routine physical'', also known as ''general medical examination'', ''periodic health evaluation'', ''annual physical'', ''comprehensive medical exam'', ''general health check'', ''preventive health examination'', ''medical check-up'', or simply ''medical'', is a physical examination performed on an asymptomatic patient for medical screening purposes. These are normally performed by a pediatrician, family practice physician, physician assistant, a certified nurse pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Milk Duct
Lactiferous ducts are ducts that converge and form a branched system connecting the nipple to the lobules of the mammary gland. When lactogenesis occurs, under the influence of hormones, the milk is moved to the nipple by the action of smooth muscle contractions along the ductal system to the tip of the nipple. They are also referred to as ''galactophores'', ''galactophorous ducts'', ''mammary ducts'', ''mamillary ducts'' or ''milk ducts''. Structure Lactiferous ducts are lined by a columnar epithelium supported by myoepithelial cells. Prior to 2005, it was thought within the areola the lactiferous duct would dilate to form the lactiferous sinus in which milk accumulates between breastfeeding sessions. However past studies have shown that the lactiferous sinus does not exist. Function The columnar epithelium plays a key role in balancing milk production, milk stasis and reabsorption. The cells of the columnar epithelium form tight junctions which are regulated by hormones and loc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microscope
A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisible to the eye unless aided by a microscope. There are many types of microscopes, and they may be grouped in different ways. One way is to describe the method an instrument uses to interact with a sample and produce images, either by sending a beam of light or electrons through a sample in its optical path, by detecting photon emissions from a sample, or by scanning across and a short distance from the surface of a sample using a probe. The most common microscope (and the first to be invented) is the optical microscope, which uses lenses to refract visible light that passed through a thinly sectioned sample to produce an observable image. Other major types of microscopes are the fluorescence microscope, electron microscope (both the transmi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duct (anatomy)
In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ. Types of ducts Examples include: Duct system As ducts travel from the acinus which generates the fluid to the target, the ducts become larger and the epithelium becomes thicker. The parts of the system are classified as follows: Some sources consider "lobar" ducts to be the same as "interlobar ducts", while others consider lobar ducts to be larger and more distal from the acinus. For sources that make the distinction, the interlobar ducts are more likely to classified with simple columnar epithelium (or pseudostratified epithelium), reserving the stratified columnar for the lobar ducts. File:Gray1025.png, Section of submaxillary gland of kitten. Duct semidiagrammatic. X 200. File:Gray1173.png, Section of portion of mamma. Intercalated duct The intercalated duct, also called intercalary duct (ducts of Boll), is the portion of an exocrine gland leading directly from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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