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Dogger Bank Itch
Dogger Bank itch is a cutaneous condition characterized by a long-lasting dermatitis caused by exposure to the sea chervil, ''Alcyonidium diaphanum'', a bryozoan. The disease, common in fishermen who work in the North Sea, has been recognized by the Danish Workman's Compensation Act since 1939. Signs and symptoms Pathogenesis The rash is caused by a type of cell-mediated hypersensitivity reaction; this type of hypersensitivity normally occurs in people who become sensitized to volatile organic compounds. Although in some instances several years may be required to develop sensitivity, this time period may vary greatly depending on the individual. In Dogger Bank itch, sensitivity is acquired after repeated handling of the sea chervils that become entangled in fishing nets. The specific toxin responsible for the rash was determined to be the sulfur-bearing salt (2-hydroxyethyl) dimethylsulfoxonium chloride. This salt is also found in some sea sponges and has potent in vitro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Skin
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin. Though nearly all human skin is covered with hair follicles, it can appear hairless. There are two general types of skin, hairy and glabrous skin (hairless). The adjective ''cutaneous'' literally means "of the skin" (from Latin ''cutis'', skin). Because it interfaces with the environment, skin plays an important immunity role in protecting the body against pathogens and excessive water loss. Its other functions are insulation, temperature regulation, sensation, synthesis of vitamin D, and the protection of vitamin B folates. Severely damaged skin will try to heal by forming scar tissue. This is often discoloured and depigmented. In humans, skin pigmentation (affected b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seaweed Dermatitis
''Lyngbya majuscula'' is a species of filamentous cyanobacteria in the genus ''Lyngbya''. It is named after the Dane Hans Christian Lyngbye. As a result of recent genetic analyses, several new genera were erected from the genus ''Lyngbya'': ''e.g.'', ''Moorea'', '' Limnoraphis'', '' Okeania'', '' Microseira'', and '' Dapis''. Almost 300 different secondary metabolites have been isolated from specimens identified as ''L. majuscula''. However, most of these studies lack a molecular identification of the samples. Several specimens identified as ''L. majuscula'' and collected in marine tropical regions are now classified as members of the genera ''Okeania'' and ''Moorea''. Antillatoxin and Kalkitoxin Kalkitoxin, a toxin derived from the cyanobacterium ''Lyngbya majuscula'', induces NMDA receptor mediated neuronal necrosis, blocks voltage-dependent sodium channels, and induces cellular hypoxia by inhibiting the electron transport chain (ETC) ... have been reported to be extra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (, , , , , etc.), hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and oxygen. It plays a vital role in an intravascular osmotic effect that keeps electrolyte concentration balanced and protects the body from infection and other blood-related disorders. Blood plasma is separated from the blood by spinning a vessel of fresh blood containing an anticoagulant in a centrifuge until the blood cells fall to the bottom of the tube. The blood plasma is t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baie De La Seine
The Baie de Seine (Bay of the Seine River) is a bay in northern France. Geography It is a wide, rectangular inlet of the English Channel, approximately 100 kilometres (east-west) by 45 kilometres, bounded in the west by the Cotentin Peninsula, in the south by the Normandy coast and in the east by the estuary of the river Seine at Le Havre. The coast alternates between sandy beaches and rocky promontories and, in general, it offers little shelter for shipping. At the western end of the bay are the Îles Saint-Marcouf. Economy Le Havre is the major port of the region; there are minor harbours at Barfleur, Port-en-Bessin, Courseulles-sur-Mer, Langrune-sur-Mer, Ouistreham, Trouville-sur-Mer and Honfleur. Domestic and foreign tourists visit the coast, given its World War II associations, sandy beaches and proximity to Paris. There are coastal resorts at Arromanches, Deauville, Cabourg, Houlgate, Villers-sur-Mer, Trouville-sur-Mer and Honfleur. History The Battles of Barfleur and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dogger Bank
Dogger Bank (Dutch: ''Doggersbank'', German: ''Doggerbank'', Danish: ''Doggerbanke'') is a large sandbank in a shallow area of the North Sea about off the east coast of England. During the last ice age the bank was part of a large landmass connecting mainland Europe and the British Isles, now known as Doggerland. It has long been known by fishermen to be a productive fishing bank; it was named after the ''Dogger (boat), doggers'', medieval Netherlands, Dutch fishing boats especially used for catching cod. At the beginning of the 21st century the area was identified as a potential site for a UK round 3 wind farm, being developed as Dogger Bank Wind Farm. Name The name Dogger Bank was first recorded in the mid-17th century. It is probably derived from the word "dogger (boat), dogger" used for a two-masted boat of the type that trawled for fish in the area in medieval times. The area has similar names in Dutch, German, and Danish. It gives its name to the Dogger sea area use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fishing Trawler
A fishing trawler is a commercial fishing vessel designed to operate Trawling, fishing trawls. Trawling is a method of fishing that involves actively dragging or pulling a trawl through the water behind one or more trawlers. Trawls are fishing nets that are pulled along the bottom of the sea or in midwater at a specified depth. A trawler may also operate two or more trawl nets simultaneously (double-rig and multi-rig). There are many variants of trawling gear. They vary according to local traditions, bottom conditions, and how large and powerful the trawling boats are. A trawling boat can be a small open boat with only 30 horsepower (22 kW) or a large factory ship with 10,000 horsepower (7457 kW). Trawl variants include beam trawls, large-opening midwater trawls, and large bottom trawls, such as "rock hoppers" that are rigged with heavy rubber wheels that let the net crawl over rocky bottom. History During the 17th century, the British developed the Dogge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sessility (zoology)
Sessility is the biological property of an organism describing its lack of a means of self-locomotion. Sessile organisms for which natural ''motility'' is absent are normally immobile. This is distinct from the botanical concept of sessility, which refers to an organism or biological structure attached directly by its base without a stalk. Sessile organisms can move via external forces (such as water currents), but are usually permanently attached to something. Organisms such as corals lay down their own substrate from which they grow. Other sessile organisms grow from a solid such as a rock, dead tree trunk, or a man-made object such as a buoy or ship's hull. Mobility Sessile animals typically have a motile phase in their development. Sponges have a motile larval stage and become sessile at maturity. Conversely, many jellyfish develop as sessile polyps early in their life cycle. In the case of the cochineal, it is in the nymph stage (also called the crawler stage) that the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signaling molecules. Hundreds of steroids are found in plants, animals and fungi. All steroids are manufactured in cells from the sterols lanosterol (opisthokonts) or cycloartenol (plants). Lanosterol and cycloartenol are derived from the cyclization of the triterpene squalene. The steroid core structure is typically composed of seventeen carbon atoms, bonded in four " fused" rings: three six-member cyclohexane rings (rings A, B and C in the first illustration) and one five-member cyclopentane ring (the D ring). Steroids vary by the functional groups attached to this four-ring core and by the oxidation state of the rings. Sterols are forms of steroids with a hydroxy group at position three and a skeleton derived from cholestane. ''A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ciclosporin
Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is a natural product. It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes). Common side effects include high blood pressure, headache, kidney problems, increased hair growth, and vomiting. Other severe side effects include an increased risk of infection, liver problems, and an increased risk of lymphoma. Blood levels of the medication should be checked to decrease the risk of side effects. Use during pregnancy may result in preterm birth; however, ciclosporin does not appear to cause birth defects. Ciclosporin is believed to work by decreasing the function of lymphocytes. It does this by forming a complex with cyclophilin to block the phosphatase activity of calcineurin, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Porifera
Sponges, the members of the phylum Porifera (; meaning 'pore bearer'), are a basal animal clade as a sister of the diploblasts. They are multicellular organisms that have bodies full of pores and channels allowing water to circulate through them, consisting of jelly-like mesohyl sandwiched between two thin layers of cells. Sponges have unspecialized cells that can transform into other types and that often migrate between the main cell layers and the mesohyl in the process. Sponges do not have nervous, digestive or circulatory systems. Instead, most rely on maintaining a constant water flow through their bodies to obtain food and oxygen and to remove wastes. Sponges were first to branch off the evolutionary tree from the last common ancestor of all animals, making them the sister group of all other animals. Etymology The term ''sponge'' derives from the Ancient Greek word ( 'sponge'). Overview Sponges are similar to other animals in that they are multicellular, hete ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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