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Dioscorea Composita
''Dioscorea composita'', or barbasco, is a species of yam in the genus '' Dioscorea'', native to Mexico. It is notable for its role in the production of diosgenin, which is a precursor for the synthesis of hormones such as progesterone. Russell Marker developed the extraction and manufacture of hormones from ''D. mexicana'' at Syntex, starting the trade of ''D. composita'' in Mexico. Marker also discovered that the ''composita'' variety had a much higher content of diosgenin than the ''mexicana'' variety, and therefore it came to replace the latter in the production of synthetic hormones. Chemical constituents Steroidal sapogenin, diosgenin. Medicinal use It is a source of diosgenin, which is used to prepare synthetic hormones such as progesterone and cortisone. Diosgenin extracted from ''Dioscorea composita'' was instrumental in the development of the combined oral contraceptive pill in the 1960s – and also for the development of cortisone treatments of arthritis. St ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl Linnaeus The Younger
Carl Linnaeus the Younger, Carolus Linnaeus the Younger, Carl von Linné den yngre (Swedish; abbreviated Carl von Linné d. y.), or ''Linnaeus filius'' (Latin for ''Linnaeus the son''; abbreviated L.fil. (outdated) or L.f. (modern) as a botanical authority; 20 January 1741 – 1 November 1783) was a Swedish naturalist. His names distinguish him from his father, the pioneering taxonomist Carl Linnaeus (1707–1778). Biography Carl Linnaeus the Younger was enrolled at the University of Uppsala at the age of nine and was taught science by his father's students, including Pehr Löfling, Daniel Solander, and Johan Peter Falk. In 1763, aged just 22, he succeeded his father as the head of Practical Medicine at Uppsala. His promotion to professor — without taking exams or defending a thesis — caused resentment among his colleagues. His work was modest in comparison to that of his father. His best-known work is the '' Supplementum Plantarum systematis vegetabilium'' of 1781, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortisone
Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys. Cortisone is converted back to the active steroid cortisol by the action of the enzyme 11β-Hydroxysteroid dehydrogenase type 1, particularly in the liver. The term "cortisone" is frequently misused to mean either any corticosteroid or hydrocortisone, which is actually another name for cortisol. Many who speak of receiving a "cortisone shot" or taking "cortisone" are actually receiving hydrocortisone or one of many other, much more potent synthetic corticosteroids; it is unlikely that the drug administered is actually cortisone. Cortisone can be administered as a prodrug, meaning it has to be converted by the body (speci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Popol Vuh
''Popol Vuh'' (also ''Popol Wuj'' or ''Popul Vuh'' or ''Pop Vuj'') is a text recounting the mythology and history of the Kʼicheʼ people, one of the Maya peoples, who inhabit Guatemala and the Mexican states of Chiapas, Campeche, Yucatan and Quintana Roo, as well as areas of Belize, Honduras and El Salvador. The ''Popol Vuh'' is a foundational sacred narrative of the Kʼicheʼ people from long before the Spanish conquest of the Maya. It includes the Mayan creation myth, the exploits of the Maya Hero Twins, Hero Twins Hunahpú and Xbalanqué, and a chronicle of the Kʼicheʼ people. The name "Popol Vuh" translates as "Book of the Community" or "Book of Counsel" (literally "Book that pertains to the mat", since a woven mat was used as a royal throne in ancient Kʼicheʼ society and symbolised the unity of the community). It was originally preserved through oral tradition until approximately 1550, when it was recorded in writing. The documentation of the ''Popol Vuh'' is credited ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papaloapan River
The Papaloapan River () is one of the main rivers of the Political divisions of Mexico, Mexican state of Veracruz (state), Veracruz. Its name comes from the Nahuatl ''papaloapan'' meaning "river of the Butterfly, butterflies". In 1517, Juan de Grijalva's expedition spotted the river, naming it Río de Alvarado.Diaz, B., 1963, The Conquest of New Spain, London: Penguin Books, The Papaloapan rises in the Sierra Madre de Oaxaca on the border between the states of Veracruz (state), Veracruz and Oaxaca. It is formed where the Santo Domingo River (Oaxaca), Santo Domingo River and the Valle Nacional River join to the southwest of San Juan Bautista Tuxtepec in Oaxaca. The Tonto River is another major tributary. The Papaloapan meanders for in a northeasterly direction through the coastal plain before draining into Alvarado Lagoon. The river basin covers , the second largest in Mexico, and contains 244 municipalities with a population of about 3.3 million people. The cities of San Juan Baut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abortifacient
An abortifacient ("that which will cause a miscarriage" from Latin: ''abortus'' "miscarriage" and '' faciens'' "making") is a substance that induces abortion. This is a nonspecific term which may refer to any number of substances or medications, ranging from herbs to prescription medications. Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. Synthetic oxytocin, which is routinely used safely during term labor, is also commonly used to induce abortion in the second or third trimester. For thousands of years writers in many parts of the world have described and recommended herbal abortifacients to women who seek to terminate a pregnancy, although their use may carry risks to the health of the woman. Medications Because "abortifacient" is a broad term used to describe a substance's effects on pregnancy, there is a wide range of drugs that can be described as abortifac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oaxaca
Oaxaca ( , also , , from nci, Huāxyacac ), officially the Free and Sovereign State of Oaxaca ( es, Estado Libre y Soberano de Oaxaca), is one of the 32 states that compose the political divisions of Mexico, Federative Entities of Mexico. It is divided into municipalities of Oaxaca, 570 municipalities, of which 418 (almost three quarters) are governed by the system of (customs and traditions) with recognized local forms of self-governance. Its capital city is Oaxaca de Juárez. Oaxaca is in southwestern Mexico. It is bordered by the states of Guerrero to the west, Puebla to the northwest, Veracruz to the north, and Chiapas to the east. To the south, Oaxaca has a significant coastline on the Pacific Ocean. The state is best known for #Indigenous peoples, its indigenous peoples and cultures. The most numerous and best known are the Zapotec peoples, Zapotecs and the Mixtecs, but there are sixteen that are officially recognized. These cultures have survived better than most others ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chinantec
The Chinantec or Chinantecan languages constitute a branch of the Oto-Manguean family. Though traditionally considered a single language, ''Ethnologue'' lists 14 partially mutually unintelligible varieties of Chinantec.Palancar, Enrique L. (2014). Revisiting the Complexity of the Chinantecan Verb Conjugation Classes. In Jean-Léo Léonard & Alain Kihm (Eds.), ''Patterns in Mesoamerican Morphology'' (pp. 77–102). HAL 01100738 The languages are spoken by the indigenous Chinantec people who live in Oaxaca and Veracruz, Mexico, especially in the districts of Cuicatlán, Ixtlán de Juárez, Tuxtepec and Choapan, and in Staten Island, New York. Internal classification Egland and Bartholomew (1978) established fourteen Chinantec languages on the basis of 80% mutual intelligibility. ''Ethnologue'' found that one that had not been adequately compared (Tlaltepusco) was not distinct, but split another (Lalana from Tepinapa). At a looser criterion of 70% intelligibility, Lalana–Tepinapa, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetic Neuropathy
Diabetic neuropathy is various types of nerve damage associated with diabetes mellitus. Symptoms depend on the site of nerve damage and can include motor changes such as weakness; sensory symptoms such as numbness, tingling, or pain; or autonomic changes such as urinary symptoms. These changes are thought to result from microvascular injury involving small blood vessels that supply nerves (vasa nervorum). Relatively common conditions which may be associated with diabetic neuropathy include distal symmetric polyneuropathy; third, fourth, or sixth cranial nerve palsy; mononeuropathy; mononeuropathy multiplex; diabetic amyotrophy; and autonomic neuropathy. Signs and symptoms Diabetic neuropathy can affect any peripheral nerves including sensory neurons, motor neurons, and the autonomic nervous system. Therefore, diabetic neuropathy has the potential to affect essentially any organ system and can cause a range of symptoms. There are several distinct syndromes based on the organ syst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthritis
Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. Onset can be gradual or sudden. There are over 100 types of arthritis. The most common forms are osteoarthritis (degenerative joint disease) and rheumatoid arthritis. Osteoarthritis usually occurs with age and affects the fingers, knees, and hips. Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. Other types include gout, lupus, fibromyalgia, and septic arthritis. They are all types of rheumatic disease. Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be useful. Recommended medications may depend on the form of arthritis. These may include pain medications such as ibuprofen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Combined Oral Contraceptive Pill
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. The pill contains two important hormones: progestin (a synthetic form of the hormone progestogen/progesterone) and estrogen (usually ethinylestradiol and 17β estradiol). When taken correctly, it alters the menstrual cycle to eliminate ovulation and prevent pregnancy. COCPs were first approved for contraceptive use in the United States in 1960, and are a very popular form of birth control. They are used by more than 100 million women worldwide and by about 9 million women in the United States. From 2015 to 2017, 12.6% of women aged 15–49 in the US reported using COCPs, making it the second most common method of contraception in this age range (female sterilization is the most common method). Use of COCPs, however, varies widely by country, age, education, and marital status. For exam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormones
A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required for the correct development of animals, plants and fungi. Due to the broad definition of a hormone (as a signaling molecule that exerts its effects far from its site of production), numerous kinds of molecules can be classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. Estrogen, oestrogen and brassinosteroid), amino acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones are used to communicate between organ (anatomy), organs and Tissue (biology), tissues. In vertebrates, hormones are responsible for regulating a variety ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yam (vegetable)
Yam is the common name for some plant species in the genus '' Dioscorea'' (family Dioscoreaceae) that form edible tubers. Yams are perennial herbaceous vines cultivated for the consumption of their starchy tubers in many temperate and tropical regions, especially in West Africa, South America and the Caribbean, Asia, and Oceania. The tubers themselves, also called "yams", come in a variety of forms owing to numerous cultivars and related species. Yams were independently domesticated on three different continents: Africa (''Dioscorea rotundata''), Asia (''Dioscorea alata''), and the Americas (''Dioscorea trifida''). Etymology The name "yam" appears to derive from Portuguese ''inhame'' or Canarian (Spain) ''ñame'', which derived from West African languages during trade. However in both languages, this name commonly refers to the taro plant (''Colocasia esculenta'') from the genus ''Colocasia'', as opposed to '' Dioscorea''. The main derivations borrow from verbs me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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