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Diffusion Theory
Photon transport in biological tissue can be equivalently modeled numerically with Monte Carlo simulations or analytically by the radiative transfer equation (RTE). However, the RTE is difficult to solve without introducing approximations. A common approximation summarized here is the diffusion approximation. Overall, solutions to the diffusion equation for photon transport are more computationally efficient, but less accurate than Monte Carlo simulations. Definitions The RTE can mathematically model the transfer of energy as photons move inside a tissue. The flow of radiation energy through a small area element in the radiation field can be characterized by radiance L(\vec,\hat,t) (\frac). Radiance is defined as energy flow per unit normal area per unit solid angle per unit time. Here, \vec denotes position, \hat denotes unit direction vector and t denotes time (Figure 1). Several other important physical quantities are based on the definition of radiance: *Fluence rate or inte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photon Transport Monte Carlo
Modeling photon propagation with Monte Carlo methods is a flexible yet rigorous approach to simulate photon transport. In the method, local rules of photon transport are expressed as probability distributions which describe the step size of photon movement between sites of photon-matter interaction and the angles of deflection in a photon's trajectory when a scattering event occurs. This is equivalent to modeling photon transport analytically by the radiative transfer equation (RTE), which describes the motion of photons using a differential equation. However, closed-form solutions of the RTE are often not possible; for some geometries, the diffusion approximation can be used to simplify the RTE, although this, in turn, introduces many inaccuracies, especially near sources and boundaries. In contrast, Monte Carlo simulations can be made arbitrarily accurate by increasing the number of photons traced. For example, see the movie, where a Monte Carlo simulation of a pencil beam inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coherence (physics)
In physics, two wave sources are coherent if their frequency and waveform are identical. Coherence is an ideal property of waves that enables stationary (i.e., temporally or spatially constant) interference. It contains several distinct concepts, which are limiting cases that never quite occur in reality but allow an understanding of the physics of waves, and has become a very important concept in quantum physics. More generally, coherence describes all properties of the correlation between physical quantities of a single wave, or between several waves or wave packets. Interference is the addition, in the mathematical sense, of wave functions. A single wave can interfere with itself, but this is still an addition of two waves (see Young's slits experiment). Constructive or destructive interference are limit cases, and two waves always interfere, even if the result of the addition is complicated or not remarkable. When interfering, two waves can add together to create a wave of g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Attenuation Coefficient
The linear attenuation coefficient, attenuation coefficient, or narrow-beam attenuation coefficient characterizes how easily a volume of material can be penetrated by a beam of light, sound, particles, or other energy or matter. A coefficient value that is large represents a beam becoming 'attenuated' as it passes through a given medium, while a small value represents that the medium had little effect on loss. The SI unit of attenuation coefficient is the reciprocal metre (m−1). Extinction coefficient is another term for this quantity, often used in meteorology and climatology. Most commonly, the quantity measures the exponential decay of intensity, that is, the value of downward ''e''-folding distance of the original intensity as the energy of the intensity passes through a unit (''e.g.'' one meter) thickness of material, so that an attenuation coefficient of 1 m−1 means that after passing through 1 metre, the radiation will be reduced by a factor of '' e'', and for material ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boundary Conditions
In mathematics, in the field of differential equations, a boundary value problem is a differential equation together with a set of additional constraints, called the boundary conditions. A solution to a boundary value problem is a solution to the differential equation which also satisfies the boundary conditions. Boundary value problems arise in several branches of physics as any physical differential equation will have them. Problems involving the wave equation, such as the determination of normal modes, are often stated as boundary value problems. A large class of important boundary value problems are the Sturm–Liouville problems. The analysis of these problems involves the eigenfunctions of a differential operator. To be useful in applications, a boundary value problem should be well posed. This means that given the input to the problem there exists a unique solution, which depends continuously on the input. Much theoretical work in the field of partial differential equ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diffusion Coefficient
Diffusivity, mass diffusivity or diffusion coefficient is a proportionality constant between the molar flux due to molecular diffusion and the gradient in the concentration of the species (or the driving force for diffusion). Diffusivity is encountered in Fick's law and numerous other equations of physical chemistry. The diffusivity is generally prescribed for a given pair of species and pairwise for a multi-species system. The higher the diffusivity (of one substance with respect to another), the faster they diffuse into each other. Typically, a compound's diffusion coefficient is ~10,000× as great in air as in water. Carbon dioxide in air has a diffusion coefficient of 16 mm2/s, and in water its diffusion coefficient is 0.0016 mm2/s. Diffusivity has dimensions of length2 / time, or m2/s in SI units and cm2/s in CGS units. Temperature dependence of the diffusion coefficient Solids The diffusion coefficient in solids at different temperatures is generally found ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fick's Law
Fick's laws of diffusion describe diffusion and were derived by Adolf Fick in 1855. They can be used to solve for the diffusion coefficient, . Fick's first law can be used to derive his second law which in turn is identical to the diffusion equation. A diffusion process that obeys Fick's laws is called normal or Fickian diffusion; otherwise, it is called anomalous diffusion or non-Fickian diffusion. History In 1855, physiologist Adolf Fick first reported* * his now well-known laws governing the transport of mass through diffusive means. Fick's work was inspired by the earlier experiments of Thomas Graham, which fell short of proposing the fundamental laws for which Fick would become famous. Fick's law is analogous to the relationships discovered at the same epoch by other eminent scientists: Darcy's law (hydraulic flow), Ohm's law (charge transport), and Fourier's Law (heat transport). Fick's experiments (modeled on Graham's) dealt with measuring the concentrations and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mean Free Path
In physics, mean free path is the average distance over which a moving particle (such as an atom, a molecule, or a photon) travels before substantially changing its direction or energy (or, in a specific context, other properties), typically as a result of one or more successive collisions with other particles. Scattering theory Imagine a beam of particles being shot through a target, and consider an infinitesimally thin slab of the target (see the figure). The atoms (or particles) that might stop a beam particle are shown in red. The magnitude of the mean free path depends on the characteristics of the system. Assuming that all the target particles are at rest but only the beam particle is moving, that gives an expression for the mean free path: :\ell = (\sigma n)^, where is the mean free path, is the number of target particles per unit volume, and is the effective cross-sectional area for collision. The area of the slab is , and its volume is . The typical number of st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spherical Harmonics
In mathematics and physical science, spherical harmonics are special functions defined on the surface of a sphere. They are often employed in solving partial differential equations in many scientific fields. Since the spherical harmonics form a complete set of orthogonal functions and thus an orthonormal basis, each function defined on the surface of a sphere can be written as a sum of these spherical harmonics. This is similar to periodic functions defined on a circle that can be expressed as a sum of circular functions (sines and cosines) via Fourier series. Like the sines and cosines in Fourier series, the spherical harmonics may be organized by (spatial) angular frequency, as seen in the rows of functions in the illustration on the right. Further, spherical harmonics are basis functions for irreducible representations of SO(3), the group of rotations in three dimensions, and thus play a central role in the group theoretic discussion of SO(3). Spherical harmonics originate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albedo
Albedo (; ) is the measure of the diffuse reflection of sunlight, solar radiation out of the total solar radiation and measured on a scale from 0, corresponding to a black body that absorbs all incident radiation, to 1, corresponding to a body that reflects all incident radiation. Surface albedo is defined as the ratio of Radiosity (radiometry), radiosity ''J''e to the irradiance ''E''e (flux per unit area) received by a surface. The proportion reflected is not only determined by properties of the surface itself, but also by the spectral and angular distribution of solar radiation reaching the Earth's surface. These factors vary with atmospheric composition, geographic location, and time (see position of the Sun). While bi-hemispherical reflectance is calculated for a single angle of incidence (i.e., for a given position of the Sun), albedo is the directional integration of reflectance over all solar angles in a given period. The temporal resolution may range from seconds (as ob ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photon Diffusion
Photon diffusion is a situation where photons travel through a material without being absorbed, but rather undergoing repeated scattering events which change the direction of their path. The path of any given photon is then effectively a random walk. A large ensemble of such photons can be said to exhibit diffusion in the material, and can be described with a diffusion equation. Astrophysics In astrophysics, photon diffusion occurs inside a stellar atmosphere. To describe this phenomenon, one should develop the transfer equation in moments and use the Eddington approximation to radiative transfer (i.e. the diffusion approximation). In 3D the results are two equations for the photon energy flux: :\vec F = -\frac\vec \nabla U, :\vec \nabla \cdot \vec F = 0, where \sigma is the opacity. By substituting the first equation into the second, one obtains the diffusion equation for the photon energy density: :\nabla^2 U -\frac\vec \nabla U \cdot \vec \nabla \sigma=0. Medical science In medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spherical Coordinate System
In mathematics, a spherical coordinate system is a coordinate system for three-dimensional space where the position of a point is specified by three numbers: the ''radial distance'' of that point from a fixed origin, its ''polar angle'' measured from a fixed zenith direction, and the ''azimuthal angle'' of its orthogonal projection on a reference plane that passes through the origin and is orthogonal to the zenith, measured from a fixed reference direction on that plane. It can be seen as the three-dimensional version of the polar coordinate system. The radial distance is also called the ''radius'' or ''radial coordinate''. The polar angle may be called '' colatitude'', ''zenith angle'', '' normal angle'', or ''inclination angle''. When radius is fixed, the two angular coordinates make a coordinate system on the sphere sometimes called spherical polar coordinates. The use of symbols and the order of the coordinates differs among sources and disciplines. This article will us ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
