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Dennis C. Liotta
Dennis Liotta is a chemistry professor at Emory University in Atlanta, Georgia, United States. He is noted for his work on the development of antiviral drugs. Career Liotta's fields of research are organic synthesis and medicinal chemistry. Along with Dr. Raymond F. Schinazi and Dr. Woo-Baeg Choi of Emory, he invented Emtricitabine, which is a breakthrough HIV drug. Emory University sold its royalties on the drug to Royalty Pharma and Gilead Sciences in July 2005 for $525 million. It is currently marketed under the name Emtriva. Emtriva is a component of a number of combination therapies used to treat HIV, including Truvada, Atripla, Complera, Stribild, Genvoya, Odefesey, Biktarvy and Descovy. Truvada is the only combination therapy approved for Pre-Exposure Prophylaxis (PrEP). Liotta, Choi and Schinazi also co-invented Epivir (lamivudine), which is a component of multiple combination therapies such as Combivir, Trizivir, Epzicom, Triumeq, Dutrebis and Delstrigo. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dennis Liotta In One Of His Lab Spaces At Emory
Dennis or Denis is a first or last name from the Greco-Roman name Dionysius, via one of the Christian saints named Dionysius. The name came from Dionysus, the Greek god of ecstatic states, particularly those produced by wine, which is sometimes said to be derived from the Greek Dios (Διός, "of Zeus") and Nysos or Nysa (Νῦσα), where the young god was raised. Dionysus (or Dionysos; also known as Bacchus in Roman mythology and associated with the Italic Liber), the Thracian god of wine, represents not only the intoxicating power of wine, but also its social and beneficent influences. He is viewed as the promoter of civilization, a lawgiver, and lover of peace—as well as the patron deity of both agriculture and the theater. Dionysus is a god of mystery religious rites, such as those practiced in honor of Demeter and Persephone at Eleusis near Athens. In the Thracian mysteries, he wears the "bassaris" or fox-skin, symbolizing new life. (See also Maenads.) A mediaeva ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biktarvy
Bictegravir/emtricitabine/tenofovir alafenamide, sold under the brand name Biktarvy, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS. One tablet, taken orally once daily, contains 50mg bictegravir, 200mg emtricitabine, and 25mg tenofovir alafenamide. It was approved for use in the United States in February 2018, and for use in the European Union in June 2018. Combination therapy Bictegravir/emtricitabine/tenofovir alafenamide is an example of a combination drug that can be taken as a complete regimen for treatment of the human immunodeficiency virus. Combination therapy for HIV, often called highly active antiretroviral therapy (HAART), is composed of two or more types of antiretroviral drugs. Combination therapy decreases the likelihood that drug resistance will occur, because it is unlikely that the HIV-1 strains will be able to mutate enough to become resistant to all drugs being used in the combination. Combination therapy increa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emory University Faculty
Emory may refer to: Places * Emory, Texas, U.S. * Emory (crater), on the moon * Emory Peak, in Texas, U.S. * Emory River, in Tennessee, U.S. Education * Emory and Henry College, or simply Emory, in Emory, Virginia, U.S. * Emory University, in Atlanta, Georgia, U.S. Other uses * Emory (name), a given name and surname, including a list of people and fictional characters with the name * Emory Marketing Institute, an American non-profit innovation research group See also * Emery (other) * Emory Creek Provincial Park, in British Columbia, Canada * Emory and Henry College Hospital * ''Quercus emoryi ''Quercus emoryi'', the Emory oak, is a species of oak common in Arizona (including inside Saguaro National Park), New Mexico and western Texas (including inside Big Bend National Park), United States, and northern Mexico ( Sonora, Chihuahua, ...'', or Emory oak * '' Carex emoryi'', or Emory's sedge * , a United States Navy submarine tender {{disambiguation, geo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gilead Sciences People
Gilead or Gilad (; he, גִּלְעָד ''Gīləʿāḏ'', ar, جلعاد, Ǧalʻād, Jalaad) is the ancient, historic, biblical name of the mountainous northern part of the region of Transjordan.''Easton's Bible Dictionary''''Galeed''/ref> The region is bounded in the west by the Jordan River, in the north by the deep ravine of the river Yarmouk and the region of Bashan, and in the southwest by what were known during antiquity as the “plains of Moab”, with no definite boundary to the east. In some cases, “Gilead” is used in the Bible to refer to all the region east of the Jordan River. Gilead is situated in modern-day Jordan, corresponding roughly to the Irbid, Ajloun, Jerash and Balqa Governorates. Gilead is also the name of three people in the Hebrew Bible, and a common given name for males in modern-day Israel. Etymology Gilead is explained in the Hebrew Bible as derived from the Hebrew words , which in turn comes from ('heap, mound, hill') and ('witness, te ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIV/AIDS Researchers
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with unintended weight loss. HIV is spread primarily by unprotected sex (including anal and vaginal sex), contaminated blood transfusions, hypodermic needles, and from mother to child during ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ACS Medicinal Chemistry Letters
''ACS Medicinal Chemistry Letters'' is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University). According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 4.632. References External links * {{American Chemical Society Journals Medicinal Chemistry Letters English-language journals Medicinal chemistry journals Publications established in 2009 Monthly journals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio State University
The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best public universities in the United States. Founded in 1870 as the state's land-grant university and the ninth university in Ohio with the Morrill Act of 1862, Ohio State was originally known as the Ohio Agricultural and Mechanical College and focused on various agricultural and mechanical disciplines, but it developed into a comprehensive university under the direction of then-Governor and later U.S. president Rutherford B. Hayes, and in 1878, the Ohio General Assembly passed a law changing the name to "the Ohio State University" and broadening the scope of the university. Admission standards tightened and became greatly more selective throughout the 2000s and 2010s. Ohio State's political science department and faculty have greatly contri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
City University Of New York
The City University of New York ( CUNY; , ) is the Public university, public university system of Education in New York City, New York City. It is the largest urban university system in the United States, comprising 25 campuses: eleven Upper division college, senior colleges, seven community colleges and seven professional institutions. While its constituent colleges date back as far as 1847, CUNY was established in 1961. The university enrolls more than 275,000 students, and counts thirteen Nobel Prize winners and twenty-four MacArthur Fellows Program, MacArthur Fellows among its alumni. History Founding In 1960, John R. Everett became the first Chancellor (education), chancellor of the Municipal college, Municipal College System of the City of New York, later renamed CUNY, for a salary of $25,000 ($ in current dollar terms). CUNY was created in 1961, by New York State legislation, signed into law by Governor Nelson Rockefeller. The legislation integrated existing institutions an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sofosbuvir
Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken Oral administration, by mouth. Common side effects include fatigue, headache, nausea, and trouble sleeping. Side effects are generally more common in interferon-containing regimens. Sofosbuvir may reactivate hepatitis B in those who have been previously infected. In combination with ledipasvir, daclatasvir or simeprevir, it is not recommended with amiodarone due to the risk of an bradycardia, abnormally slow heartbeat. Sofosbuvir is in the nucleotide analog family of medications and works by blocking the hepatitis C NS5B protein. Sofosbuvir was discovered in 2007 and approved for medical use in the United States in 2013. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. Medical uses Initial HCV treatment In 2016, the American Association for the Study of Liver Diseases and the Infectious Diseases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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