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Deming Regression
In statistics, Deming regression, named after W. Edwards Deming, is an errors-in-variables model which tries to find the line of best fit for a two-dimensional dataset. It differs from the simple linear regression in that it accounts for errors in observations on both the ''x''- and the ''y''- axis. It is a special case of total least squares, which allows for any number of predictors and a more complicated error structure. Deming regression is equivalent to the maximum likelihood estimation of an errors-in-variables model in which the errors for the two variables are assumed to be independent and normally distributed, and the ratio of their variances, denoted ''δ'', is known. In practice, this ratio might be estimated from related data-sources; however the regression procedure takes no account for possible errors in estimating this ratio. The Deming regression is only slightly more difficult to compute than the simple linear regression. Most statistical software packages used ...
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Total Least Squares
In applied statistics, total least squares is a type of errors-in-variables regression, a least squares data modeling technique in which observational errors on both dependent and independent variables are taken into account. It is a generalization of Deming regression and also of orthogonal regression, and can be applied to both linear and non-linear models. The total least squares approximation of the data is generically equivalent to the best, in the Frobenius norm, low-rank approximation of the data matrix. Linear model Background In the least squares method of data modeling, the objective function, ''S'', :S=\mathbf, is minimized, where ''r'' is the vector of residuals and ''W'' is a weighting matrix. In linear least squares the model contains equations which are linear in the parameters appearing in the parameter vector \boldsymbol\beta, so the residuals are given by :\mathbf. There are ''m'' observations in y and ''n'' parameters in β with ''m''>''n''. X is a '' ...
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Trigonometry
Trigonometry () is a branch of mathematics that studies relationships between side lengths and angles of triangles. The field emerged in the Hellenistic world during the 3rd century BC from applications of geometry to astronomical studies. The Greeks focused on the calculation of chords, while mathematicians in India created the earliest-known tables of values for trigonometric ratios (also called trigonometric functions) such as sine. Throughout history, trigonometry has been applied in areas such as geodesy, surveying, celestial mechanics, and navigation. Trigonometry is known for its many identities. These trigonometric identities are commonly used for rewriting trigonometrical expressions with the aim to simplify an expression, to find a more useful form of an expression, or to solve an equation. History Sumerian astronomers studied angle measure, using a division of circles into 360 degrees. They, and later the Babylonians, studied the ratios of the sides of ...
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American Mathematical Monthly
''The American Mathematical Monthly'' is a mathematical journal founded by Benjamin Finkel in 1894. It is published ten times each year by Taylor & Francis for the Mathematical Association of America. The ''American Mathematical Monthly'' is an expository journal intended for a wide audience of mathematicians, from undergraduate students to research professionals. Articles are chosen on the basis of their broad interest and reviewed and edited for quality of exposition as well as content. In this the ''American Mathematical Monthly'' fulfills a different role from that of typical mathematical research journals. The ''American Mathematical Monthly'' is the most widely read mathematics journal in the world according to records on JSTOR. Tables of contents with article abstracts from 1997–2010 are availablonline The MAA gives the Lester R. Ford Awards annually to "authors of articles of expository excellence" published in the ''American Mathematical Monthly''. Editors *2022– ...
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The Mathematical Gazette
''The Mathematical Gazette'' is an academic journal of mathematics education, published three times yearly, that publishes "articles about the teaching and learning of mathematics with a focus on the 15–20 age range and expositions of attractive areas of mathematics." It was established in 1894 by Edward Mann Langley as the successor to the Reports of the Association for the Improvement of Geometrical Teaching. Its publisher is the Mathematical Association. William John Greenstreet was its editor for more than thirty years (1897–1930). Since 2000, the editor is Gerry Leversha. Editors * Edward Mann Langley: 1894-1896 * Francis Sowerby Macaulay: 1896-1897 * William John Greenstreet: 1897-1930 * Alan Broadbent: 1930-1955 * Reuben Goodstein: 1956-1962 * Edwin A. Maxwell: 1962-1971 * Douglas Quadling Douglas Arthur Quadling (1926–2015) was an English mathematician, school master and educationalist who was one of the four drivers behind the School Mathematics Project (SMP) i ...
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Line Fitting
Line fitting is the process of constructing a straight line that has the best fit to a series of data points. Several methods exist, considering: *Vertical distance: Simple linear regression **Resistance to outliers: Robust simple linear regression *Perpendicular distance: Orthogonal regression **Weighted geometric distance: Deming regression *Scale invariance: Major axis regression See also *Linear least squares *Linear segmented regression *Linear trend estimation *Polynomial regression *Regression dilution Regression dilution, also known as regression attenuation, is the biasing of the linear regression slope towards zero (the underestimation of its absolute value), caused by errors in the independent variable. Consider fitting a straight line f ... Further reading *"Fitting lines", chap.1 in LN. Chernov (2010), ''Circular and linear regression: Fitting circles and lines by least squares'', Chapman & Hall/CRC, Monographs on Statistics and Applied Probability, Volume 11 ...
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Synthetic Biological Circuit
Synthetic biological circuits are an application of synthetic biology where biological parts inside a cell are designed to perform logical functions mimicking those observed in electronic circuits. The applications range from simply inducing production to adding a measurable element, like GFP, to an existing natural biological circuit, to implementing completely new systems of many parts. The goal of synthetic biology is to generate an array of tunable and characterized parts, or modules, with which any desirable synthetic biological circuit can be easily designed and implemented. These circuits can serve as a method to modify cellular functions, create cellular responses to environmental conditions, or influence cellular development. By implementing rational, controllable logic elements in cellular systems, researchers can use living systems as engineered "biological machines" to perform a vast range of useful functions. History The first natural gene circuit studied in detail ...
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Cellular Noise
Cellular noise is random variability in quantities arising in cellular biology. For example, cells which are genetically identical, even within the same tissue, are often observed to have different expression levels of proteins, different sizes and structures. These apparently random differences can have important biological and medical consequences. Cellular noise was originally, and is still often, examined in the context of gene expression levels – either the concentration or copy number of the products of genes within and between cells. As gene expression levels are responsible for many fundamental properties in cellular biology, including cells' physical appearance, behaviour in response to stimuli, and ability to process information and control internal processes, the presence of noise in gene expression has profound implications for many processes in cellular biology. Definitions The most frequent quantitative definition of noise is the coefficient of variation: : \et ...
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Ellipse
In mathematics, an ellipse is a plane curve surrounding two focus (geometry), focal points, such that for all points on the curve, the sum of the two distances to the focal points is a constant. It generalizes a circle, which is the special type of ellipse in which the two focal points are the same. The elongation of an ellipse is measured by its eccentricity (mathematics), eccentricity e, a number ranging from e = 0 (the Limiting case (mathematics), limiting case of a circle) to e = 1 (the limiting case of infinite elongation, no longer an ellipse but a parabola). An ellipse has a simple algebraic solution for its area, but only approximations for its perimeter (also known as circumference), for which integration is required to obtain an exact solution. Analytic geometry, Analytically, the equation of a standard ellipse centered at the origin with width 2a and height 2b is: : \frac+\frac = 1 . Assuming a \ge b, the foci are (\pm c, 0) for c = \sqrt. The standard parametric e ...
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Steiner Inellipse
In geometry, the Steiner inellipse,Weisstein, E. "Steiner Inellipse" — From MathWorld, A Wolfram Web Resource, http://mathworld.wolfram.com/SteinerInellipse.html. midpoint inellipse, or midpoint ellipse of a triangle is the unique ellipse inscribed in the triangle and tangent to the sides at their midpoints. It is an example of an inellipse. By comparison the inscribed circle and Mandart inellipse of a triangle are other inconics that are tangent to the sides, but not at the midpoints unless the triangle is equilateral. The Steiner inellipse is attributed by Dörrie to Jakob Steiner, and a proof of its uniqueness is given by Dan Kalman.. The Steiner inellipse contrasts with the Steiner circumellipse, also called simply the Steiner ellipse, which is the unique ellipse that passes through the vertices of a given triangle and whose center is the triangle's centroid. Definition and properties ;Definition An ellipse that is tangent to the sides of a triangle at its midpoints M_1 ...
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Vertex (geometry)
In geometry, a vertex (in plural form: vertices or vertexes) is a point (geometry), point where two or more curves, line (geometry), lines, or edge (geometry), edges meet. As a consequence of this definition, the point where two lines meet to form an angle and the corners of polygons and polyhedron, polyhedra are vertices. Definition Of an angle The ''vertex'' of an angle is the point where two Line (mathematics)#Ray, rays begin or meet, where two line segments join or meet, where two lines intersect (cross), or any appropriate combination of rays, segments, and lines that result in two straight "sides" meeting at one place. :(3 vols.): (vol. 1), (vol. 2), (vol. 3). Of a polytope A vertex is a corner point of a polygon, polyhedron, or other higher-dimensional polytope, formed by the intersection (Euclidean geometry), intersection of Edge (geometry), edges, face (geometry), faces or facets of the object. In a polygon, a vertex is called "convex set, convex" if the internal an ...
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Triangle
A triangle is a polygon with three Edge (geometry), edges and three Vertex (geometry), vertices. It is one of the basic shapes in geometry. A triangle with vertices ''A'', ''B'', and ''C'' is denoted \triangle ABC. In Euclidean geometry, any three points, when non-Collinearity, collinear, determine a unique triangle and simultaneously, a unique Plane (mathematics), plane (i.e. a two-dimensional Euclidean space). In other words, there is only one plane that contains that triangle, and every triangle is contained in some plane. If the entire geometry is only the Euclidean plane, there is only one plane and all triangles are contained in it; however, in higher-dimensional Euclidean spaces, this is no longer true. This article is about triangles in Euclidean geometry, and in particular, the Euclidean plane, except where otherwise noted. Types of triangle The terminology for categorizing triangles is more than two thousand years old, having been defined on the very first page of ...
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Line (geometry)
In geometry, a line is an infinitely long object with no width, depth, or curvature. Thus, lines are one-dimensional objects, though they may exist in two, three, or higher dimension spaces. The word ''line'' may also refer to a line segment in everyday life, which has two points to denote its ends. Lines can be referred by two points that lay on it (e.g., \overleftrightarrow) or by a single letter (e.g., \ell). Euclid described a line as "breadthless length" which "lies evenly with respect to the points on itself"; he introduced several postulates as basic unprovable properties from which he constructed all of geometry, which is now called Euclidean geometry to avoid confusion with other geometries which have been introduced since the end of the 19th century (such as non-Euclidean, projective and affine geometry). In modern mathematics, given the multitude of geometries, the concept of a line is closely tied to the way the geometry is described. For instance, in analytic ...
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