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DNA Viruses
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two realms: ''Duplodnaviria'' and ''Varidnaviria'', and ssDNA viruses are almost exclusively assigned to the realm ''Monodnaviria'', which also includes some dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Reverse transcribing viruses, which have a DNA genome that is replicated through an RNA intermediate by a reverse transcriptase, are classified into the kingdom ''Pararnavirae'' in the realm ''Riboviria''. DNA viruses are ubiquitous worldwide, especially in marine environments where they form an important part of marine ecosystems, and infect both prokaryotes and eukaryotes. They ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cowpox Virus
Cowpox is an infectious disease caused by the ''cowpox virus'' (CPXV). It presents with large vesicle (dermatology), blisters in the skin, a fever and lymphadenopathy, swollen glands, historically typically following contact with an infected cow, though in the last several decades more often (though overall rarely) from infected cats. The hands and face are most frequently affected and the spots are generally very painful. The virus, part of the genus ''Orthopoxvirus'', is closely related to the ''vaccinia'' virus. The virus is Zoonosis, zoonotic, meaning that it is transferable between species, such as from cat to human. The transferral of the disease was first observed in dairymaids who touched the udders of infected cows and consequently developed the signature pustules on their hands.Vanessa Ngan, "Viral and Skin Inf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poxviridae
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cann , a city in France
{{disambiguation ...
Cann may refer to: *Cann (surname), a list of people with the name *Cann River, a river of Victoria, Australia *Cann, Dorset, a village in England *Edward du Cann, British businessman and politician *Claire and Antoinette Cann pianists, known as the Cann Twins *Cann baronets, a former baronetcy See also * Cann Hall, a district of the London Borough of Waltham Forest * McCann (other) * Kann (other) * Can (other) * Canne (other) * Cannes Cannes ( , , ; oc, Canas) is a city located on the French Riviera. It is a communes of France, commune located in the Alpes-Maritimes departments of France, department, and host city of the annual Cannes Film Festival, Midem, and Cannes Lions I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytoplasm
In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The main components of the cytoplasm are cytosol (a gel-like substance), the organelles (the cell's internal sub-structures), and various cytoplasmic inclusions. The cytoplasm is about 80% water and is usually colorless. The submicroscopic ground cell substance or cytoplasmic matrix which remains after exclusion of the cell organelles and particles is groundplasm. It is the hyaloplasm of light microscopy, a highly complex, polyphasic system in which all resolvable cytoplasmic elements are suspended, including the larger organelles such as the ribosomes, mitochondria, the plant plastids, lipid droplets, and vacuoles. Most cellular activities take place within the cytoplasm, such as many metabolic pathways including glycolysis, and proces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Replicative Transposition
Replicative transposition is a mechanism of transposition in molecular biology, proposed by James A. Shapiro in 1979, in which the transposable element is duplicated during the reaction, so that the transposing entity is a copy of the original element. In this mechanism, the donor and receptor DNA sequences form a characteristic intermediate "theta" configuration, sometimes called a "Shapiro intermediate". Replicative transposition is characteristic to retrotransposon Retrotransposons (also called Class I transposable elements or transposons via RNA intermediates) are a type of genetic component that copy and paste themselves into different genomic locations (transposon) by converting RNA back into DNA through ...s and occurs from time to time in class II transposons.. References {{DEFAULTSORT:Replicative Transposition Mobile genetic elements ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fermin
Fermin (also Firmin, from Latin ''Firminus''; Spanish ''Fermín'') was a legendary holy man and martyr, traditionally venerated as the co-patron saint of Navarre, Spain. His death may be associated with either the Decian persecution (250) or Diocletianic Persecution (303).Roger Collins, ''The Basques'' (Blackwell, 1986), p. 61: "In this tale there exists not an iota of truth". Although he is said to have lived in the third century, Fermin's legend is a creation of the ninth century. It probably originates in the diocese of Toulouse, which endeavoured to spread the devotion to Saint Fermin. If there was a historical Fermin he is wholly unknown and was probably no more than a name on a tombstone around which an edifying legend was crafted. According to the legend, a senator from Pamplona named Firmus was converted to Christianity by Honestus and persuaded Saturninus to come to Pamplona to baptise him. There the bishop preached to large crowds and baptised some 40,000 people over t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rampersad
Rampersad also spelt as Ramprasad or Rampersaud is a surname common in Trinidad and Tobago, Guyana, Suriname, the Caribbean, Fiji, South Africa, and Mauritius. It is of Indian and Hindu origin, derived from the Sanskrit words Rama Prasada, and is not affiliated with any certain caste. In India it is used as a first name, but the descendants of the indentured laborers in the European colonies used their fathers' first name as their surname. The name is common among Caribbean Hindus, but also as a result of ethnic mixing. It is also common in Christians as well. Many people of this surname have migrated to the United States and Canada as well. Sundar Popo wrote a song called ''Rampersad''. Ramprasad is a common name among Bhojpuri (a Hindi dialect) speaking areas of the states of Bihar and Uttar Pradesh of northern and eastern India. From 1834 to 1917, indentured plantation workers from this region were dispersed far and wide across the world including the Caribbean, Suriname, Fiji a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyadenylation
Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases. In eukaryotes, polyadenylation is part of the process that produces mature mRNA for translation. In many bacteria, the poly(A) tail promotes degradation of the mRNA. It, therefore, forms part of the larger process of gene expression. The process of polyadenylation begins as the transcription of a gene terminates. The 3′-most segment of the newly made pre-mRNA is first cleaved off by a set of proteins; these proteins then synthesize the poly(A) tail at the RNA's 3′ end. In some genes these proteins add a poly(A) tail at one of several possible sites. Therefore, polyadenylation can produce more than one transcript from a single gene (alternative polyadenylation), similar to alternative splicing. The poly(A) tail is important for the nuclea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA Polymerase
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that synthesizes RNA from a DNA template. Using the enzyme helicase, RNAP locally opens the double-stranded DNA so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription. A transcription factor and its associated transcription mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only initiates RNA transcription, it also guides the nucleotides into position, facilitates attachment and elongation, has intrinsic proofreading and replacement capabilities, and termination recognition capability. In eukaryotes, RNAP can build chains as long as 2.4 million nucleotides. RNAP produces RNA that, functionally, is either for protein coding, i.e. messenger RNA (mRNA); or n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription Preinitiation Complex
The preinitiation complex (abbreviated PIC) is a complex of approximately 100 proteins that is necessary for the transcription of protein-coding genes in eukaryotes and archaea. The preinitiation complex positions RNA polymerase II at gene transcription start sites, denatures the DNA, and positions the DNA in the RNA polymerase II active site for transcription. The minimal PIC includes RNA polymerase II and six general transcription factors: TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. Additional regulatory complexes (such as the mediator coactivator and chromatin remodeling complexes) may also be components of the PIC. Assembly A classical view of PIC formation at the promoter involves the following steps: * TATA binding protein (TBP, a subunit of TFIID) binds the promoter, creating a sharp bend in the promoter DNA. ** Animals have some TBP-related factors (TRF; TBPL1/ TBPL2). They can replace TBP in some special contexts. * TBP recruits TFIIA, then TFIIB, to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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