Cyrus Chothia
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Cyrus Chothia
Cyrus Homi Chothia (19 February 1942 – 26 November 2019) was an English biochemist who was an emeritus scientist at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) at the University of Cambridge and emeritus fellow of Wolfson College, Cambridge. Education Chothia was educated at Alleyn's School, then went to study at Durham University graduating with a Bachelor of Science degree in 1965. Chothia then completed a Master of Science degree at Birkbeck College in 1967 and a PhD from University College London under the supervision of , the son of Linus Pauling. Research and career After his PhD Chothia worked in the Laboratory of Molecular Biology (LMB) for three years. He then worked with Michael Levitt at the Weizmann Institute of Science followed by two years with Joel Janin at the Institut Pasteur in Paris. In 1976 Chothia returned to England to work at University College London and the LMB. With Arthur Lesk he showed that proteins adapt to mut ...
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Alex Bateman
Alexander George Bateman is a computational biologist and Head of Protein Sequence Resources at the European Bioinformatics Institute (EBI), part of the European Molecular Biology Laboratory (EMBL) in Cambridge, UK. He has led the development of the Pfam biological database and introduced the Rfam database of RNA families. He has also been involved in the use of Wikipedia for community-based annotation of biological databases. Education Bateman received a Bachelor of Science degree in Biochemistry from Newcastle University in 1994. He received his PhD from the University of Cambridge in 1997, for research supervised by Cyrus Chothia on the evolution of the immunoglobulin protein superfamily. During this time, he also worked with Sean Eddy to discover novel protein domains using the HMMER software. Career and research In 1997, Bateman joined the Wellcome Trust Sanger Institute to lead the development of the Pfam biological database. In 2003, he introduced the Rfam data ...
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Intelligent Systems For Molecular Biology
Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational methods for biological problems. The conference has been held every year since 1993 and has grown to become one of the largest and most prestigious meetings in these fields, hosting over 2,000 delegates in 2004. From the first meeting, ISMB has been held in locations worldwide; since 2007, meetings have been located in Europe and North America in alternating years. Since 2004, European meetings have been held jointly with the European Conference on Computational Biology (ECCB). The main ISMB conference is usually held over three days and consists of presentations, poster sessions and keynote talks. Most presentations are given in multiple parallel tracks; however, key ...
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Julian Gough (scientist)
Julian John Thurstan Gough (born 1974) is a Group Leader in the Laboratory of Molecular Biology (LMB) of the Medical Research Council (MRC). He was previously a professor of bioinformatics at the University of Bristol. Education Gough was educated at The Perse School in Cambridge and the University of Bristol where he was awarded a joint honours degree in Mathematics and Physics in 1998. He went on to complete his PhD in the Laboratory of Molecular Biology (LMB) supervised by Cyrus Chothia on genome analysis and protein structure as a postgraduate student of Sidney Sussex College, Cambridge, graduating in 2001. Career and research Following his PhD, Gough completed postdoctoral research at the LMB and Stanford University, with Michael Levitt. Subsequently, he was a scientist at RIKEN in Tokyo before being appointed a member of faculty at the University of Bristol, where he has worked since 2007. He has also been a visiting scientist at the Pasteur Institute in Paris and an a ...
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Structural Classification Of Proteins Database
The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins. Proteins with the same shapes but having little sequence or functional similarity are placed in different superfamilies, and are assumed to have only a very distant common ancestor. Proteins having the same shape and some similarity of sequence and/or function are placed in "families", and are assumed to have a closer common ancestor. Similar to CATH and Pfam databases, SCOP provides a classification of individual structural domains of proteins, rather than a classification of the entire proteins which may include a significant number of different domains. The SCOP database is freely accessible on the internet. SCOP was created in 1994 in the Centre for Protein Engineering and the Labo ...
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Tim Hubbard
Timothy John Phillip Hubbard is a Professor of Bioinformatics at King's College London, Head of Genome Analysis at Genomics England and Honorary Faculty at the Wellcome Trust Sanger Institute in Cambridge, UK. Education Hubbard was educated at the University of Cambridge where he was awarded a Bachelor of Arts degree in Natural Sciences (Cambridge), Natural Sciences (Biochemistry) in 1985. He went on to do research in protein design in the Crystallography, Department of Crystallography, Birkbeck, University of London, Birkbeck College, London where he was awarded a Doctor of Philosophy, PhD in 1988 for research supervised by Tom Blundell. Research and career Hubbard's research interests are in Bioinformatics, Computational biology and Genome Bioinformatics, Informatics. During his tenure at WTSI he supervised several successful PhD students to completion in these areas of research. Hubbard was appointed Professor of Bioinformatics at King's in October 2013. His research has been ...
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Linus Pauling
Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time, and as of 2000, he was rated the 16th most important scientist in history. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie, John Bardeen, Frederick Sanger and Karl Barry Sharpless). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions t ...
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Wolfson College, Cambridge
Wolfson College () is a colleges of the University of Cambridge, constituent college of the University of Cambridge in Cambridge, England. The majority of students at the college are postgraduate education, postgraduates. The college also admits Adult learner, "mature" Undergraduate education, undergraduates (aged 21 and above), with around 15% of students studying undergraduate degree courses at the university. The college was founded in 1965 as "University College", but was refounded as Wolfson College in 1973 in recognition of the benefaction of the Wolfson Foundation. Wolfson is located to the south-west of Cambridge city centre, near the Cambridge University Library, University Library. As one of the more modern colleges in Cambridge, Wolfson does not follow all of the traditions of some of the university's older colleges. For example, since the college's founding there has been no "High Table" reserved for Fellows at Formal Hall dinners; students and Fellows mix and di ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ...
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Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ...
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Dan David Prize
The Dan David Prize is a major international award that recognizes and supports outstanding contributions to the study of history and other disciplines that shed light on the human past. It awards nine prizes of $300,000 each year to outstanding early- and mid-career scholars and practitioners in the historical disciplines. The Prize has an annual purse of $3 million, making it the largest history award in the world, with the remaining $300,000 funding an international postdoctoral fellowship program at Tel Aviv University, where the Prize is headquartered. The Prize is endowed by the Dan David Foundation. Until 2021 the Prize awarded 3 annual prizes of $1 million for innovative and interdisciplinary research in three time dimensions: Past, Present and Future. Prize laureates donated 10 percent of their prize money to doctoral scholarships for outstanding Ph.D. students and postdoctoral scholarships in their own field from around the world. In September 2021, the Dan David Prize ...
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ISCB Senior Scientist Awards
The ISCB Accomplishment by a Senior Scientist Award is an annual prize awarded by the International Society for Computational Biology for contributions to the field of computational biology. Laureates *2021 - Peer Bork *2020 - Steven Salzberg *2019 - Bonnie Berger *2018 - Ruth Nussinov *2017 - Pavel Pevzner *2016 - Søren Brunak *2015 - Cyrus Chothia *2014 - Eugene Myers, Gene Myers *2013 - David Eisenberg *2012 - Gunnar von Heijne *2011 - Michael Ashburner *2010 - Chris Sander (Scientist), Chris Sander *2009 - Webb Miller *2008 - David Haussler *2007 - Temple F. Smith *2006 - Michael Waterman *2005 - Janet Thornton *2004 - David J. Lipman *2003 - David Sankoff References

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