Cynanchum Auriculatum
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Cynanchum Auriculatum
''Vincetoxicum auriculatum'', synonym ''Cynanchum auriculatum'', is a species of climbing vine. Its Chinese name is ''niu pi xiao'' 牛皮消 (leather eater). ''V. auriculatum'' flowers between June and August; fruiting from August all the way to December. Distribution and habitat ''Vincetoxicum auriculatum'' is native to Asian temperate and tropical regions; found in China (in Sichuan, Xizang, and Yunnan provinces), Bhutan, Nepal, and the northern parts of Pakistan and India (it is also native to Kashmir). Its habitat is mountainous shrubland terrain, at elevations from 2800 to 3600 meters. Studies Ethanol extracts derived from roots of ''V. auriculatum'' are being studied for use in anti-cancer medicine; one preliminary study found extracts to have some cytotoxic effects on certain human tumor cell lines. The tests were conducted, both ''in vitro'' and ''in vivo'', on both human subjects, and mice. References External linksA photoof ''C. auriculatum'', from ...
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John Forbes Royle
John Forbes Royle (10 May 1798 – 2 January 1858), British botanist and teacher of materia medica, was born in Kanpur (then Cawnpore) in 1798. He was in charge of the botanical garden at Saharanpur and played a role in the development of economic botany in India. Early life John Forbes Royle was the only son of William Henry Royle and Isabella Forbes. While still a child, his father died and Royle studied under Sangster of Haddington before going to study at Edinburgh high school. He was influenced by Anthony Todd Thomson to take an interest in botany and natural history. This led him to give up a military career at Addiscombe and chose to study medicine. He joined the service of the East India Company as assistant surgeon and went to Calcutta in 1819. He served with the Bengal army (at various times with the 17th and 87th Regiments, Native Artillery, Cavalry and Infantry) at Dum-Dum and in parts of the North-Western Provinces where he found time to study botany and geology, a ...
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Mountain
A mountain is an elevated portion of the Earth's crust, generally with steep sides that show significant exposed bedrock. Although definitions vary, a mountain may differ from a plateau in having a limited Summit (topography), summit area, and is usually higher than a hill, typically rising at least 300 metres (1,000 feet) above the surrounding land. A few mountains are Monadnock, isolated summits, but most occur in mountain ranges. Mountain formation, Mountains are formed through Tectonic plate, tectonic forces, erosion, or volcanism, which act on time scales of up to tens of millions of years. Once mountain building ceases, mountains are slowly leveled through the action of weathering, through Slump (geology), slumping and other forms of mass wasting, as well as through erosion by rivers and glaciers. High elevations on mountains produce Alpine climate, colder climates than at sea level at similar latitude. These colder climates strongly affect the Montane ecosystems, ecosys ...
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Harvard University Herbaria
The Harvard University Herbaria and Botanical Museum are institutions located on the grounds of Harvard University at 22 Divinity Avenue, Cambridge, Massachusetts. The Botanical Museum is one of three which comprise the Harvard Museum of Natural History. The Herbaria, founded in 1842 by Asa Gray, are one of the 10 largest in the world with over 5 million specimens, and including the Botany Libraries, form the world's largest university owned herbarium. The Gray Herbarium is named after him. HUH hosts the Gray Herbarium Index (GCI) as well as an extensive specimen, botanist, and publications database. HUH was the center for botanical research in the United States of America by the time of its founder's retirement in the 1870s. The materials deposited there are one of the three major sources for the International Plant Names Index. The Botanical museum was founded in 1858. It was originally called the ''Museum of Vegetable Products'' and was predominantly focused on an interdisc ...
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Flora Of China (journal)
''Flora of China'' is a scientific publication aimed at describing the plants native to China. The project is a collaborative scientific effort to publish the first modern English-language account of the 31,000 species of vascular plants of China. This number includes about 8,000 species of medicinal and economically important plants and about 7,500 species of trees and shrubs. ''Flora of China'' describes and otherwise documents these species. ''Flora of China'' is an English-language revision of (FRPS), with taxonomy reflecting the current understanding of each group. The sequence of families is a modified Englerian system, similar to that used in FRPS; however, the circumscription of some families reflects the present understanding of the groups. It is intended that all the vascular plants of China will be covered, including descriptions, identification keys, essential synonymy, phenology, provincial distribution in China, brief statements on extra-Chinese distribution, ...
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John Wiley & Sons
John Wiley & Sons, Inc., commonly known as Wiley (), is an American multinational publishing company founded in 1807 that focuses on academic publishing and instructional materials. The company produces books, journals, and encyclopedias, in print and electronically, as well as online products and services, training materials, and educational materials for undergraduate, graduate, and continuing education students. History The company was established in 1807 when Charles Wiley opened a print shop in Manhattan. The company was the publisher of 19th century American literary figures like James Fenimore Cooper, Washington Irving, Herman Melville, and Edgar Allan Poe, as well as of legal, religious, and other non-fiction titles. The firm took its current name in 1865. Wiley later shifted its focus to scientific, technical, and engineering subject areas, abandoning its literary interests. Wiley's son John (born in Flatbush, New York, October 4, 1808; died in East Orange, New Je ...
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Phytotherapy Research
''Phytotherapy Research'' is a monthly peer-reviewed scientific journal publishing original research papers, short communications, reviews, and letters on medicinal plant research. Key areas of interest are pharmacology, toxicology, and the clinical applications of herbs and natural products in medicine, from case histories to full clinical trials, including studies of herb-drug interactions and other aspects of the safety of herbal medicines. Papers concerned with the effects of common food ingredients and standardised plant extracts, including commercial products, are particularly relevant, as are mechanistic studies on isolated natural products. The editor-in-chief is Angelo Izzo (University of Naples). Impact factor According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citation ...
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Mice
A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not taxonomically specific. Typical mice are classified in the genus '' Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, ''Peromyscus''. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding a ...
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In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done ''in vitro'' ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In dr ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially m ...
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Cytotoxicity
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells with the cytotoxic compound can result in a variety of cell fates. The cells may undergo necrosis, in which they lose membrane integrity and die rapidly as a result of cell lysis. The cells can stop actively growing and dividing (a decrease in cell viability), or the cells can activate a genetic program of controlled cell death (apoptosis). Cells undergoing necrosis typically exhibit rapid swelling, lose membrane integrity, shut down metabolism, and release their contents into the environment. Cells that undergo rapid necrosis in vitro do not have sufficient time or energy to activate apoptotic machinery and will not express apoptotic markers. Apoptosis is characterized by well defined cytological and molecular events including a change i ...
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Cancer Research
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. History Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identif ...
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