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Cucurbitacin E
Cucurbitacin E is a biochemical compound from the family of cucurbitacins. These are found in plants which are member of the family Cucurbitaceae, most of them coming from traditional Chinese medicinal plants, but also in other plants such as pumpkins and gourds. Cucurbitacin E is a highly oxidated steroid consisting of a tetracyclic triterpene. Specific modifications in this molecule under certain conditions can form other types of cucurbitacins such as cucurbitacin I, J, K and L. , it is being investigated for its potential biological effects. Cucurbitacin E has been found to increase activity of anti-cancer drugs in certain types of cancers. It selectively increases Chemosensitivity assay, chemosensitivity of nutrient receptors, on or inside cancer cells, to anti-cancer drug molecules, thereby decreasing binding of the nutrients to cancer cells, and decreasing their growth, leading to selective cell death of cancer cells. Research Anti-inflammatory Cucurbitacin E anti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cucurbitacin
Cucurbitacin is a class of biochemical compounds that some plants – notably members of the pumpkin and gourd family, Cucurbitaceae – produce and which function as a defence against herbivores. Cucurbitacins are chemically classified as triterpenes, formally derived from cucurbitane, a triterpene hydrocarbon – specifically, from the unsaturated variant cucurbit-5-ene, or 19(10→9β)-abeo-10α-lanost-5-ene. They often occur as glycosides. They and their derivatives have been found in many plant families (including Brassicaceae, Cucurbitaceae, Scrophulariaceae, Begoniaceae, Elaeocarpaceae, Datiscaceae, Desfontainiaceae, Polemoniaceae, Primulaceae, Rubiaceae, Sterculiaceae, Rosaceae, and Thymelaeaceae), in some mushrooms (including Russula and Hebeloma) and even in some marine mollusks. Cucurbitacins may be a taste deterrent in plants foraged by some animals and in some edible plants preferred by humans, like cucumbers and zucchinis. In laboratory research, cucurbitacins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
