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Craniodiaphyseal Dysplasia
Craniodiaphyseal dysplasia (CDD), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy. These calcium deposits decrease the size of cranial foramina, and can decrease the circumference of the cervical spinal canal. In the few cases recorded, most died in childhood. Cause The underlying genetics are uncertain. Diagnosis Among the medical signs are dacryocystitis, seizures, intellectual disability, and paralysis, each of which is a complication resulting from the diminutive foramina. A common sign reported as a result of the disease has been widely spaced eyes. In media Peter Bogdanovich's 1985 drama film ''Mask'' drew public attention to the case of Roy Lee "Rocky" Dennis, an American boy with disorder who died at the age of 16, in 1978. In the American medical drama ''Grey's Anatomy'' episode " Yesterday", Jesse Plemons plays a teenage boy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autosomal Recessive
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and the second recessive. This state of having two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes ( autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one copy of the Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, there are other forms of dominance such as incomplete d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roy L
Roy is a masculine given name and a family surname with varied origin. In Anglo-Norman England, the name derived from the Norman ''roy'', meaning "king", while its Old French cognate, ''rey'' or ''roy'' (modern ''roi''), likewise gave rise to Roy as a variant in the Francophone world. In India, Roy is a variant of the surname ''Rai'',. likewise meaning "king".. It also arose independently in Scotland, an anglicisation from the Scottish Gaelic nickname ''ruadh'', meaning "red". Given name * Roy Acuff (1903–1992), American country music singer and fiddler * Roy Andersen (born 1955), runner * Roy Andersen (South Africa) (born 1948), South African businessman and military officer * Roy Anderson (American football) (born 1980), American football coach * Sir Roy M. Anderson (born 1947), British scientific adviser * Roy Andersson (born 1943), Swedish film director * Roy Andersson (footballer) (born 1949), footballer from Sweden * Roy Chapman Andrews (1884–1960), American natu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autosomal Recessive Disorders
An autosome is any chromosome that is not a sex chromosome. The members of an autosome pair in a diploid cell have the same morphology, unlike those in allosomal (sex chromosome) pairs, which may have different structures. The DNA in autosomes is collectively known as atDNA or auDNA. For example, humans have a diploid genome that usually contains 22 pairs of autosomes and one allosome pair (46 chromosomes total). The autosome pairs are labeled with numbers (1–22 in humans) roughly in order of their sizes in base pairs, while allosomes are labelled with their letters. By contrast, the allosome pair consists of two X chromosomes in females or one X and one Y chromosome in males. Unusual combinations of XYY, XXY, XXX, XXXX, XXXXX or XXYY, among other Salome combinations, are known to occur and usually cause developmental abnormalities. Autosomes still contain sexual determination genes even though they are not sex chromosomes. For example, the SRY gene on the Y chromosome e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Disorders Of Musculoskeletal System
A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of a body part and functional disorders in which problems exist with how a body part works. Functional disorders include metabolic and degenerative disorders. Some birth defects include both structural and functional disorders. Birth defects may result from genetic or chromosomal disorders, exposure to certain medications or chemicals, or certain infections during pregnancy. Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. Many are believed to involve multiple factors. Birth defects may be visib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leontiasis Ossea
Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. It is not a disease in itself, but a symptom of other diseases, including Paget's disease, fibrous dysplasia, hyperparathyroidism and renal osteodystrophy. The common form is that in which one or other maxilla is affected, its size progressively increasing, and thus encroaching on the cavities of the orbit, the mouth, the nose and its accessory sinuses. Exophthalmos gradually develops, going on later to a complete loss of sight due to compression of the optic nerve by the overgrowth of bone. There may also be interference with the nasal respiration and with the taking of food. In the somewhat less common form of this rare disease the overgrowth of bone affects all the cranial bones as well as those of the face, the senses being lost one by one and death finally resulting from cerebral pressure. There is no treatm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Horror Story
''American Horror Story'' is an American anthology horror television series created by Ryan Murphy and Brad Falchuk for the cable network FX. The first installment in the '' American Story'' media franchise, each season is conceived as a self-contained miniseries, following a different set of characters and settings in the same fictional universe, and a storyline with its own "beginning, middle, and end." Some plot elements of each season are loosely inspired by true events. Many actors appear in more than one season, often playing a new character. Evan Peters, Sarah Paulson, and Lily Rabe have returned most frequently, with each appearing in at least nine of the first eleven seasons, followed by Frances Conroy, who appears in eight, and Denis O'Hare appearing in seven. Other notable actors such as Jessica Lange, Kathy Bates, Angela Bassett, Emma Roberts, Adina Porter, Finn Wittrock, Jamie Brewer, Billie Lourd, and Leslie Grossman appear in five of the eleven seasons. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wildstorm Productions
Wildstorm Productions, (stylized as WildStorm), is an American comic book imprint. Originally founded as an independent company established by Jim Lee under the name "Aegis Entertainment" and expanded in subsequent years by other creators, Wildstorm became a publishing imprint of DC Comics in 1999. Until it was shut down in 2010, the Wildstorm imprint remained editorially separate from DC Comics, with its main studio located in California. The imprint took its name from the combining of the titles of the Jim Lee comic series '' WildC.A.T.S.'' and '' Stormwatch''. Its main fictional universe, the Wildstorm Universe, featured costumed heroes. Wildstorm maintained a number of its core titles from its early period, and continued to publish material expanding its core universe. Its main titles included ''WildC.A.T.S'', ''Stormwatch'', ''Gen¹³'', ''Wetworks'', and '' The Authority''; it also produced single-character-oriented series like '' Deathblow'' and ''Midnighter'', and publish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
How I Spent My Summer Vacation
How I Spent My Summer Vacation may refer to: * ''How I Spent My Summer Vacation'' (album), a 2001 album by the Bouncing Souls * ''How I Spent My Summer Vacation'' (1967 film), an American television film * ''How I Spent My Summer Vacation'' (1997 film), an American romantic comedy film * ''How I Spent My Summer Vacation'' (2012 film) or ''Get the Gringo'', an American crime thriller film See also * " How I Spent My Strummer Vacation", a 2002 episode of ''The Simpsons'' * '' Tiny Toon Adventures: How I Spent My Vacation'', a 1992 American animated film {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jesse Plemons
Jesse Plemons (; born April 2, 1988) is an American actor. He began his career as a child actor and achieved a career breakthrough with his major role as Landry Clarke in the NBC drama series '' Friday Night Lights'' (2006–2011). He subsequently portrayed Todd Alquist in season 5 of the AMC crime drama series ''Breaking Bad'' (2012–2013) and its sequel film '' El Camino: A Breaking Bad Movie'' (2019). For his role as Ed Blumquist in season 2 of the FX anthology series '' Fargo'' (2015), he received his first Primetime Emmy Award nomination and won a Critics' Choice Television Award. He received a second Emmy nomination for his portrayal of Robert Daly in "USS Callister", an episode of the Netflix anthology series ''Black Mirror'' (2017). Plemons has appeared in supporting roles in several films including '' The Master'' (2012), ''The Homesman'' (2014), '' Black Mass'', '' Bridge of Spies'' (both 2015), '' Game Night'', ''Vice'' (both 2018), ''The Irishman'' (2019), ''Judas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grey's Anatomy (Season 2)
The second season of the American television medical drama ''Grey's Anatomy'' commenced airing on the American Broadcasting Company (ABC) on September 25, 2005, and concluded on May 15, 2006. The season was produced by Touchstone Television, in association with Shondaland production company and The Mark Gordon Company, the showrunner being Shonda Rhimes. Actors Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, and T. R. Knight reprised their roles as surgical interns Meredith Grey, Cristina Yang, Izzie Stevens, Alex Karev, and George O'Malley respectively. Previous main cast members Chandra Wilson, James Pickens, Jr., Isaiah Washington and Patrick Dempsey also returned, while Kate Walsh, who began the season in a recurring capacity, was promoted to series-regular status, after appearing in 7 episodes as a guest-star. The season continued to focus on the surgical residency of five young interns as they try to balance the challenges of their competitive careers with t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grey's Anatomy
''Grey's Anatomy'' is an American medical drama television series that premiered on March 27, 2005, on ABC as a mid-season replacement. The series focuses on the lives of surgical interns, residents, and attendings as they develop into seasoned doctors while balancing personal and professional relationships. The title is an allusion to '' Gray's Anatomy'', a classic human anatomy textbook first published in 1858 in London and written by Henry Gray. Shonda Rhimes developed the pilot and continued to write for the series until 2015. Krista Vernoff, who previously worked with Rhimes, is now the showrunner. Rhimes was also one of the executive producers alongside Betsy Beers, Mark Gordon, Krista Vernoff, Rob Corn, Mark Wilding, Allan Heinberg, and Ellen Pompeo. Although the series is set in Seattle, Washington, it is filmed primarily in Los Angeles, California, and Vancouver, British Columbia. The series revolves around Ellen Pompeo's character, Dr. Meredith Grey, until halfwa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Drama
A medical drama is a television show or film in which events center upon a hospital, an ambulance staff, or any medical environment. Most recent medical drama (film and television), dramatic programming go beyond the events pertaining to the characters' jobs and portray some aspects of their personal lives. A typical medical drama might have a storyline in which two doctors fall in love. Communication theory, Communications theorist Marshall McLuhan, in his Understanding Media: The Extensions of Man, 1964 work on the nature of Mass media, media, predicted success for this particular genre on TV because the medium "creates an obsession with bodily welfare". The longest running medical drama in the world is the British series ''Casualty (TV series), Casualty'', airing since 1986, and the longest running medical soap opera is General Hospital running since 1963. History ''City Hospital (U.S. TV series), City Hospital'', which first aired in 1951, is usually considered to be the first ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
