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Cranial Nerve
Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck, including the special senses of vision, taste, smell, and hearing. The cranial nerves emerge from the central nervous system above the level of the first vertebra of the vertebral column. Each cranial nerve is paired and is present on both sides. There are conventionally twelve pairs of cranial nerves, which are described with Roman numerals I–XII. Some considered there to be thirteen pairs of cranial nerves, including cranial nerve zero. The numbering of the cranial nerves is based on the order in which they emerge from the brain and brainstem, from front to back. The terminal nerves (0), olfactory nerves (I) and optic nerves (II) emerge from the cerebrum, and the remaining ten pairs arise ...
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Skull Base
The base of skull, also known as the cranial base or the cranial floor, is the most inferior area of the skull. It is composed of the endocranium and the lower parts of the calvaria. Structure Structures found at the base of the skull are for example: Bones There are five bones that make up the base of the skull: * Ethmoid bone * Sphenoid bone * Occipital bone *Frontal bone *Temporal bone Sinuses * Occipital sinus * Superior sagittal sinus *Superior petrosal sinus Foramina of the skull * Foramen cecum *Optic foramen *Foramen lacerum *Foramen rotundum *Foramen magnum *Foramen ovale * Jugular foramen * Internal auditory meatus *Mastoid foramen *Sphenoidal emissary foramen *Foramen spinosum Sutures *Frontoethmoidal suture *Sphenofrontal suture *Sphenopetrosal suture *Sphenoethmoidal suture *Petrosquamous suture *Sphenosquamosal suture Other * Sphenoidal lingula * Subarcuate fossa *Dorsum sellae *Jugular process * Petro-occipital fissure *Condylar canal *Jugular tubercl ...
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Olfactory Nerve
The olfactory nerve, also known as the first cranial nerve, cranial nerve I, or simply CN I, is a cranial nerve that contains sensory nerve fibers relating to the sense of smell. The afferent nerve fibers of the olfactory receptor neurons transmit nerve impulses about odors to the central nervous system ( olfaction). Derived from the embryonic nasal placode, the olfactory nerve is somewhat unusual among cranial nerves because it is capable of some regeneration if damaged. The olfactory nerve is sensory in nature and originates on the olfactory mucosa in the upper part of the nasal cavity. From the olfactory mucosa, the nerve (actually many small nerve fascicles) travels up through the cribriform plate of the ethmoid bone to reach the surface of the brain. Here the fascicles enter the olfactory bulb and synapse there; from the bulbs (one on each side) the olfactory information is transmitted into the brain via the olfactory tract. The fascicles of the olfactory nerve are no ...
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Vestibulocochlear Nerve
The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. Through olivocochlear fibers, it also transmits motor and modulatory information from the superior olivary complex in the brainstem to the cochlea. Structure The vestibulocochlear nerve consists mostly of bipolar neurons and splits into two large divisions: the cochlear nerve and the vestibular nerve. Cranial nerve 8, the vestibulocochlear nerve, goes to the middle portion of the brainstem called the pons (which then is largely composed of fibers going to the cerebellum). The 8th cranial nerve runs between the base of the pons and medulla oblongata (the lower portion of the brainstem). This junction between the pons, medulla, and cerebellum that contains the 8th nerve is called the cerebellopontine angle. The vestibulocochlear ne ...
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Facial Nerve
The facial nerve, also known as the seventh cranial nerve, cranial nerve VII, or simply CN VII, is a cranial nerve that emerges from the pons of the brainstem, controls the muscles of facial expression, and functions in the conveyance of taste sensations from the anterior two-thirds of the tongue. The nerve typically travels from the pons through the facial canal in the temporal bone and exits the skull at the stylomastoid foramen. It arises from the brainstem from an area posterior to the cranial nerve VI (abducens nerve) and anterior to cranial nerve VIII (vestibulocochlear nerve). The facial nerve also supplies preganglionic parasympathetic fibers to several head and neck ganglia. The facial and intermediate nerves can be collectively referred to as the nervus intermediofacialis. The path of the facial nerve can be divided into six segments: # intracranial (cisternal) segment # meatal (canalicular) segment (within the internal auditory canal) # labyrinthine segment (i ...
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Abducens Nerve
The abducens nerve or abducent nerve, also known as the sixth cranial nerve, cranial nerve VI, or simply CN VI, is a cranial nerve in humans and various other animals that controls the movement of the lateral rectus muscle, one of the extraocular muscles responsible for outward gaze. It is a somatic efferent nerve. Structure Nucleus The abducens nucleus is located in the pons, on the floor of the fourth ventricle, at the level of the facial colliculus. Axons from the facial nerve loop around the abducens nucleus, creating a slight bulge (the facial colliculus) that is visible on the dorsal surface of the floor of the fourth ventricle. The abducens nucleus is close to the midline, like the other motor nuclei that control eye movements (the oculomotor and trochlear nuclei). Motor axons leaving the abducens nucleus run ventrally and caudally through the pons. They pass lateral to the corticospinal tract (which runs longitudinally through the pons at this level) before e ...
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Trigeminal Nerve
In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewing; it is the most complex of the cranial nerves. Its name ("trigeminal", ) derives from each of the two nerves (one on each side of the pons) having three major branches: the ophthalmic nerve (V), the maxillary nerve (V), and the mandibular nerve (V). The ophthalmic and maxillary nerves are purely sensory, whereas the mandibular nerve supplies motor as well as sensory (or " cutaneous") functions. Adding to the complexity of this nerve is that autonomic nerve fibers as well as special sensory fibers ( taste) are contained within it. The motor division of the trigeminal nerve derives from the basal plate of the embryonic pons, and the sensory division originates in the cranial neural crest. Sensory information from the face and ...
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Trochlear Nerve
The trochlear nerve (), ( lit. ''pulley-like'' nerve) also known as the fourth cranial nerve, cranial nerve IV, or CN IV, is a cranial nerve that innervates just one muscle: the superior oblique muscle of the eye, which operates through the pulley-like trochlea. CN IV is a motor nerve only (a somatic efferent nerve), unlike most other CNs. The trochlear nerve is unique among the cranial nerves in several respects: * It is the ''smallest'' nerve in terms of the number of axons it contains. * It has the greatest intracranial length. * It is the only cranial nerve that exits from the dorsal (rear) aspect of the brainstem. * It innervates a muscle, the superior oblique muscle, on the opposite side (contralateral) from its nucleus. The trochlear nerve decussates within the brainstem before emerging on the contralateral side of the brainstem (at the level of the inferior colliculus). An injury to the trochlear nucleus in the brainstem will result in an contralateral superior o ...
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Oculomotor Nerve
The oculomotor nerve, also known as the third cranial nerve, cranial nerve III, or simply CN III, is a cranial nerve that enters the orbit through the superior orbital fissure and innervates extraocular muscles that enable most movements of the eye and that raise the eyelid. The nerve also contains fibers that innervate the intrinsic eye muscles that enable pupillary constriction and accommodation (ability to focus on near objects as in reading). The oculomotor nerve is derived from the basal plate of the embryonic midbrain. Cranial nerves IV and VI also participate in control of eye movement. Structure The oculomotor nerve originates from the third nerve nucleus at the level of the superior colliculus in the midbrain. The third nerve nucleus is located ventral to the cerebral aqueduct, on the pre-aqueductal grey matter. The fibers from the two third nerve nuclei located laterally on either side of the cerebral aqueduct then pass through the red nucleus. From the red n ...
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Cranial Nerve Nucleus
A cranial nerve nucleus is a collection of neurons (gray matter) in the brain stem that is associated with one or more of the cranial nerves. Axons carrying information to and from the cranial nerves form a synapse first at these nuclei. Lesions occurring at these nuclei can lead to effects resembling those seen by the severing of nerve(s) they are associated with. All the nuclei except that of the trochlear nerve (CN IV) supply nerves of the same side of the body. Structure Motor and sensory In general, motor nuclei are closer to the front (ventral), and sensory nuclei and neurons are closer to the back (dorsal). This arrangement mirrors the arrangement of tracts in the spinal cord. * Close to the midline are the motor efferent nuclei, such as the oculomotor nucleus, which control skeletal muscle. Just lateral to this are the autonomic (or visceral) efferent nuclei. * There is a separation, called the sulcus limitans, and lateral to this are the sensory nuclei. Near the sulcus l ...
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Human Brain
The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sense organs, and making decisions as to the instructions sent to the rest of the body. The brain is contained in, and protected by, the skull bones of the head. The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six neuronal layers, while the allocortex has three or four. Each hemisphere is conventionally divided into four lobes – the frontal, temporal, parietal, and oc ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the ...
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Spinal Nerve
A spinal nerve is a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body. In the human body there are 31 pairs of spinal nerves, one on each side of the vertebral column. These are grouped into the corresponding cervical, thoracic, lumbar, sacral and coccygeal regions of the spine. There are eight pairs of cervical nerves, twelve pairs of thoracic nerves, five pairs of lumbar nerves, five pairs of sacral nerves, and one pair of coccygeal nerves. The spinal nerves are part of the peripheral nervous system. Structure Each spinal nerve is a mixed nerve, formed from the combination of nerve fibers from its dorsal and ventral roots. The dorsal root is the afferent sensory root and carries sensory information to the brain. The ventral root is the efferent motor root and carries motor information from the brain. The spinal nerve emerges from the spinal column through an opening ( intervertebral foramen) between adjacent verteb ...
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