Coumaphos
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Coumaphos
Coumaphos is a nonvolatile, fat-soluble phosphorothioate with ectoparasiticide properties: it kills insects and mites. It is well known by a variety of brand names as a dip or wash, used on farm and domestic animals to control ticks, mites, flies and fleas. It is also used to control ''Varroa'' mites in honey bee colonies, though in many areas it is falling out of favor as the mites develop resistance and as the residual toxicity effects are becoming better understood. In Australia, its registration as suited to home veterinary use was cancelled by the Australian Pesticides and Veterinary Medicines Authority in June 2004 after the manufacturer failed to show it was safe for use on pets. The compound has been linked to neurological problems in bees, and may be a factor in colony collapse. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act The Emergency Planning ...
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Diseases Of The Honeybee
Diseases of the honey bee or abnormal hive conditions include: Pests and parasites ''Varroa'' mites ''Varroa destructor'' and ''V. jacobsoni'' are parasitic mites that feed on the fat bodies of adult, pupal and larval bees. When the hive is very heavily infested, ''Varroa'' mites can be seen with the naked eye as a small red or brown spot on the bee's thorax. ''Varroa'' mites are carriers for many viruses that are damaging to bees. For example, bees infected during their development will often have visibly deformed wings. ''Varroa'' mites have led to the virtual elimination of feral bee colonies in many areas, and are a major problem for kept bees in apiaries. Some feral populations are now recovering—it appears they have been naturally selected for ''Varroa'' resistance. ''Varroa'' mites were first discovered in Southeast Asia in about 1904, but are now present on all continents except Australia. They were discovered in the United States in 1987, in New Zealand in ...
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Phosphorothioate
Thiophosphates (or phosphorothioates, PS) are chemical compounds and anions with the general chemical formula (''x'' = 0, 1, 2, or 3) and related derivatives where organic groups are attached to one or more O or S. Thiophosphates feature tetrahedral phosphorus(V) centers. Organic Organothiophosphates are a subclass of organophosphorus compounds that are structurally related to the inorganic thiophosphates. Common members have formulas of the type (RO)3−''x''R''x''PS and related compounds where RO is replaced by RS. Many of these compounds are used as insecticides, some have medical applications, and some have been used as oil additives.J. Svara, N. Weferling, T. Hofmann "Phosphorus Compounds, Organic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2006. Oligonucleotide phosphorothioates (OPS) are modified oligonucleotides where one of the oxygen atoms in the phosphate moiety is replaced by sulfur. They are the basis of antisense therapy, e.g., the d ...
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List Of Extremely Hazardous Substances
This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002). The list can be found as an appendix to 40 C.F.R. 355. Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). The data were provided by the United States Environmental Protection Agency (EPA). __NOTOC__ A * Acetone cyanohydrin * Acetone thiosemicarbazide * Acrolein * Acrylamide * Acrylonitrile * Acryloyl chloride * Adiponitrile * Aldicarb * Aldrin * Allyl alcohol * Allylamine * Aluminum phosphide * Aminopterin * Amiton * Amiton oxalate * Ammonia * Amphetamine * Aniline * Aniline, 2,4,6-trimethyl- * Antimony pentafluoride * Antimycin A * ANTU (Alpha-Naphthylthiourea) * Arsenic pentoxide * Arsenous oxide * Arsenous trichloride * Arsine * Azinphos-ethyl * Azinphos-methyl B * Benzal chloride * Benzenamine, 3-(trifluoromethyl)- * Benzenearsonic acid * Benzimidazole, 4,5-dichloro-2-(tri ...
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Coumarin Drugs
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It can be placed in the benzopyrone chemical class and considered as a lactone. Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. By inhibiting synthesis of vitamin K, a related compound is used as the prescription drug warfarin – an anticoagulant – to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism. Etymology Coumarin is derived from ''coumarou'', the French word for the tonka bean. The word ''tonka'' for the tonka bean is taken from the Galibi (Carib) tongue spoken by natives of French Guia ...
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Organophosphate Insecticides
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered as esters of phosphoric acid. Like most functional groups, organophosphates occur in a diverse range of forms, with important examples including key biomolecules such as DNA, RNA and ATP, as well as many insecticides, herbicides, nerve agents and flame retardants. OPEs have been widely used in various products as flame retardants, plasticizers, and performance additives to engine oil. The popularity of OPEs as flame retardants came as a substitution for the highly regulated brominated flame retardants. The low cost of production and compatibility to diverse polymers made OPEs to be widely used in industry including textile, furniture, electronics as plasticizers and flame retardants. These compounds are added to the final product physica ...
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Acetylcholinesterase Inhibitors
Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors. Acetylcholinesterase inhibitors are one of two types of cholinesterase inhibitors; the other being butyryl-cholinesterase inhibitors. Acetylcholinesterase is the primary member of the cholinesterase enzyme family. Acetylcholinesterase inhibitors are classified as reversible, irreversible, or quasi-irreversible (also called pseudo-irreversible). Mechanism of action Organophosphates Organophosphates like TEPP and sarin inhibit cholinesterases, enzymes that hydrolyze the neurotransmitter acetylcholine. The active centre of cholinesterases feature two important sites, namely th ...
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United States Government Publishing Office
The United States Government Publishing Office (USGPO or GPO; formerly the United States Government Printing Office) is an agency of the legislative branch of the United States Federal government. The office produces and distributes information products and services for all three branches of the Federal Government, including U.S. passports for the Department of State as well as the official publications of the Supreme Court, the Congress, the Executive Office of the President, executive departments, and independent agencies. An act of Congress changed the office's name to its current form in 2014. History The Government Printing Office was created by congressional joint resolution () on June 23, 1860. It began operations March 4, 1861, with 350 employees and reached a peak employment of 8,500 in 1972. The agency began transformation to computer technology in the 1980s; along with the gradual replacement of paper with electronic document distribution, this has led to a stea ...
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Emergency Planning And Community Right-to-Know Act
The Emergency Planning and Community Right-to-Know Act of 1986 is a United States federal law passed by the 99th United States Congress located at Title 42, Chapter 116 of the U.S. Code, concerned with emergency response preparedness. On October 17, 1986, President Ronald Reagan signed into law the Superfund Amendments and Reauthorization Act of 1986 (SARA). This act amended the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), commonly known as Superfund. A free-standing law, the Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA) was commonly known as SARA Title III. Its purpose is to encourage and support emergency planning efforts at the state and local levels and to provide the public and local governments with information concerning potential chemical hazards present in their communities. Background During the early morning hours of December 3, 1984, a Union Carbide plant in a village just South of Bhopal, India rel ...
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Veterinarian
A veterinarian (vet), also known as a veterinary surgeon or veterinary physician, is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, vets also play a role in animal reproduction, animal health management, conservation, husbandry and breeding and preventive medicine like animal nutrition, vaccination and parasitic control as well as biosecurity and zoonotic disease surveillance and prevention. Description In many countries, the local nomenclature for a veterinarian is a regulated and protected term, meaning that members of the public without the prerequisite qualifications and/or licensure are not able to use the title. This title is selective in order to produce the most knowledgeable veterinarians that pass these qualifications. In many cases, the activities that may be undertaken by a veterinarian (such as treatment of illness or surgery in animals) are restricted only t ...
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APVMA
The Australian Pesticides and Veterinary Medicines Authority (APVMA) is the Australian Government The Australian Government, also known as the Commonwealth Government, is the national government of Australia, a federal parliamentary constitutional monarchy. Like other Westminster-style systems of government, the Australian Government ... statutory agency responsible for the management and regulation of all agricultural and Veterinary medicine, veterinary chemical products in Australia. History The APVMA was established on 15 June 1993 as the National Registration Authority for Agricultural and Veterinary Chemicals, under the ''Agricultural and Veterinary Chemicals (Administration) Act 1992''. Current responsibilities Any agricultural or veterinary product that is manufactured, sold, imported, or used in Australia must first be registered by the APVMA. To be registered, the process may include scientific evaluations of the safety and efficacy of the product. See also * ...
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Ectoparasiticide
An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. These drugs are used to kill the parasites that live on the body surface. Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). It is a prescription, lotion-based medicine that is applied to the whole body to get rid of the scabies parasite that ... are well known ectoparasiticides. Permethrin Broad-spectrum and potent pyrethroid insecticide  and is most convenient for both scabies and lice. First choice drug. 100% cure rate. Causes neurological paralysis in insects probably by delaying depolarisation. Crotamiton Second choice drug. Effective scabicide, pediculocide and antipruritic. Cure rate 60-88%. Benzyl benzoate 2nd line drug for scabies and is seldom used for pediculosis. Cure rate 76-100% Lindane Effective in trea ...
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Australia
Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, smaller islands. With an area of , Australia is the largest country by area in Oceania and the world's List of countries and dependencies by area, sixth-largest country. Australia is the oldest, flattest, and driest inhabited continent, with the least fertile soils. It is a Megadiverse countries, megadiverse country, and its size gives it a wide variety of landscapes and climates, with Deserts of Australia, deserts in the centre, tropical Forests of Australia, rainforests in the north-east, and List of mountains in Australia, mountain ranges in the south-east. The ancestors of Aboriginal Australians began arriving from south east Asia approximately Early human migrations#Nearby Oceania, 65,000 years ago, during the Last Glacial Period, last i ...
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