Compound Spirit Of Ether
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Compound Spirit Of Ether
Compound spirit of ether, also called Hoffmann's anodyne, Hoffmann's drops, or aetheris spiritus compositus, is a solution of one part diethyl ether in three parts alcohol. It is used traditionally as an anodyne or as a hypnotic. Its use as a drug was introduced by Friedrich Hoffmann Friedrich Hoffmann or Hofmann (19 February 1660 – 12 November 1742) was a German physician and chemist. He is also sometimes known in English as Frederick Hoffmann. Life His family had been connected with medicine for 200 years before him. Bo ....T. Kleij: ''Zur Entwicklungs- und Herstellungsgeschichte der "Hoffmannstropfen" und ihrer Darstellung und Interpretation in den medizinischen Werken des 19. und 20. Jahrhunderts''. Dresden, 2003. References Traditional medicine {{nervous-system-drug-stub ...
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Diethyl Ether
Diethyl ether, or simply ether, is an organic compound in the ether class with the formula , sometimes abbreviated as (see Pseudoelement symbols). It is a colourless, highly volatile, sweet-smelling ("ethereal odour"), extremely flammable liquid. It is commonly used as a solvent in laboratories and as a starting fluid for some engines. It was formerly used as a general anesthetic, until non-flammable drugs were developed, such as halothane. It has been used as a recreational drug to cause intoxication. Production Most diethyl ether is produced as a byproduct of the vapor-phase hydration of ethylene to make ethanol. This process uses solid-supported phosphoric acid catalysts and can be adjusted to make more ether if the need arises. Vapor-phase dehydration of ethanol over some alumina catalysts can give diethyl ether yields of up to 95%. Diethyl ether can be prepared both in laboratories and on an industrial scale by the acid ether synthesis. Ethanol is mixed with a ...
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Ethanol
Ethanol (abbr. EtOH; also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound. It is an alcohol with the chemical formula . Its formula can be also written as or (an ethyl group linked to a hydroxyl group). Ethanol is a volatile, flammable, colorless liquid with a characteristic wine-like odor and pungent taste. It is a psychoactive recreational drug, the active ingredient in alcoholic drinks. Ethanol is naturally produced by the fermentation process of sugars by yeasts or via petrochemical processes such as ethylene hydration. It has medical applications as an antiseptic and disinfectant. It is used as a chemical solvent and in the synthesis of organic compounds, and as a fuel source. Ethanol also can be dehydrated to make ethylene, an important chemical feedstock. As of 2006, world production of ethanol was , coming mostly from Brazil and the U.S. Etymology ''Ethanol'' is the systematic name defined by the ...
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Anodyne
An anodyne is a drug used to lessen pain through reducing the sensitivity of the brain or nervous system. The term was common in medicine before the 20th century, but such drugs are now more often known as analgesics or painkillers. The term ''anodyne'' derives from Greek ''anōdynos'' (), from ''an-'' (, "without") and ''odynē'' (, "pain"). Etymologically, the word covers any substance that reduces pain, but doctors used it more narrowly. Some definitions restrict the term to topical medications, including herbal simples such as onion, lily, root of mallows, leaves of violet, and elderberry. Other definitions include ingested narcotics, hypnotics, and opioids. In the 19th century, the primary anodynes were opium, henbane, hemlock, tobacco, nightshade (stramonium), and chloroform. Certain compound medicines were also called by this name, such as anodyne balsam, made of castile soap, camphor, saffron, and spirit of wine ''Aqua vitae'' (Latin for "water of life") o ...
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Hypnotic
Hypnotic (from Greek ''Hypnos'', sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy. The word is also used in art.) and to treat insomnia (sleeplessness). This group of drugs is related to sedatives''. ''Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the term hypnotic generally describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness), they are often referred to collectively as sedative- ...
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Friedrich Hoffmann
Friedrich Hoffmann or Hofmann (19 February 1660 – 12 November 1742) was a German physician and chemist. He is also sometimes known in English as Frederick Hoffmann. Life His family had been connected with medicine for 200 years before him. Born in Halle, he attended the local gymnasium where he acquired that taste for and skill in mathematics to which he attributed much of his later success. Beginning at age 18, he studied medicine at the University of Jena. From there, in 1680, he went to Erfurt, to attend Kasper Cramer's lectures on chemistry. Next year, returning to Jena, he received his doctor's diploma, and, after publishing a thesis, was permitted to teach. Constant study then began to tell on his health, and in 1682, leaving his already numerous pupils, he opened a practice in Minden at the request of a relative who held a high position in that town. After practising at Minden for two years, Hoffmann made a journey to Holland and England, where he formed the acquaintanc ...
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